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Protein
Submitted name:

Receptor of-activated protein C kinase 1

Gene

RACK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

SignaLinkiD6RAC2.

Names & Taxonomyi

Protein namesi
Submitted name:
Receptor of-activated protein C kinase 1Imported
Gene namesi
Name:RACK1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000204628.11.
HGNCiHGNC:4399. RACK1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204628.

PTM / Processingi

Proteomic databases

MaxQBiD6RAC2.
PeptideAtlasiD6RAC2.
PRIDEiD6RAC2.

Expressioni

Gene expression databases

BgeeiENSG00000204628.
ExpressionAtlasiD6RAC2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6RAC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 269WD_REPEATS_REGIONInterPro annotationAdd BLAST259
Repeati11 – 53WDPROSITE-ProRule annotationAdd BLAST43
Repeati59 – 100WDPROSITE-ProRule annotationAdd BLAST42
Repeati96 – 139WDPROSITE-ProRule annotationAdd BLAST44
Repeati140 – 181WDPROSITE-ProRule annotationAdd BLAST42
Repeati239 – 269WDPROSITE-ProRule annotationAdd BLAST31

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00890000139419.
HOGENOMiHOG000091643.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiView protein in InterPro
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF00400. WD40. 6 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00320. WD40. 6 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

D6RAC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET
60 70 80 90 100
NYGIPQRALR GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTQDESHS
110 120 130 140 150
EWVSCVRFSP NSSNPIIVSC GWDKLVKVWN LANCKLKTNH IGHTGYLNTV
160 170 180 190 200
TVSPDGSLCA SGGKDGQAML WDLNEGKHLY TLDGGDIINA LCFSPNRYWL
210 220 230 240 250
CAATGPSIKI WDLEGKIIVD ELKQEVISTS SKAEPPQCTS LAWSADGQTL
260
FAGYTDNLVR VWQVTIGTR
Length:269
Mass (Da):29,751
Last modified:July 13, 2010 - v1
Checksum:i1C7BB50A0D3AE2F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008443 Genomic DNA. No translation available.
KC877161 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000511900; ENSP00000422768; ENSG00000204628.
UCSCiuc063kxl.1. human.

Similar proteinsi

Entry informationi

Entry nameiD6RAC2_HUMAN
AccessioniPrimary (citable) accession number: D6RAC2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: September 27, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported