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Protein
Submitted name:

Receptor of-activated protein C kinase 1

Gene

RACK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

SignaLinkiD6R9Z1

Names & Taxonomyi

Protein namesi
Submitted name:
Receptor of-activated protein C kinase 1Imported
Gene namesi
Name:RACK1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000204628.11
HGNCiHGNC:4399 RACK1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204628

PTM / Processingi

Proteomic databases

PeptideAtlasiD6R9Z1
PRIDEiD6R9Z1

Expressioni

Gene expression databases

BgeeiENSG00000204628
ExpressionAtlasiD6R9Z1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6R9Z1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 215WD_REPEATS_REGIONInterPro annotationAdd BLAST193
Repeati45 – 86WDPROSITE-ProRule annotationAdd BLAST42
Repeati87 – 119WDPROSITE-ProRule annotationAdd BLAST33
Repeati130 – 173WDPROSITE-ProRule annotationAdd BLAST44
Repeati174 – 215WDPROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0279 Eukaryota
ENOG410XQGZ LUCA
GeneTreeiENSGT00910000144232
HOGENOMiHOG000091643

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00400 WD40, 4 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 4 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 4 hits
PS50082 WD_REPEATS_2, 4 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Fragment.

D6R9Z1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLHSSLGDR ARLHLKKKKS YQDKTIIMWK LTRDETNYGI PQRALRGHSH
60 70 80 90 100
FVSDVVISSD GQFALSGSWD GTLRLWDLTT GTTTRRFVGH TKDVLSVAFS
110 120 130 140 150
SDNRQIVSGS RDKTIKLWNT LGVCKYTVQD ESHSEWVSCV RFSPNSSNPI
160 170 180 190 200
IVSCGWDKLV KVWNLANCKL KTNHIGHTGY LNTVTVSPDG SLCASGGKDG
210 220 230
QAMLWDLNEG KHLYTLDGGD IINALCFSPN RYWLCA
Length:236
Mass (Da):26,349
Last modified:October 5, 2016 - v8
Checksum:iC18924FF1EEB5F6E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei236Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008443 Genomic DNA No translation available.
KC877161 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000502844; ENSP00000422029; ENSG00000204628
UCSCiuc063kxo.1 human

Similar proteinsi

Entry informationi

Entry nameiD6R9Z1_HUMAN
AccessioniPrimary (citable) accession number: D6R9Z1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 64 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health