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Protein
Submitted name:

Ankyrin-2

Gene

ANK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Ankyrin-2Imported
Gene namesi
Name:ANK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:493. ANK2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000145362.

PTM / Processingi

Proteomic databases

EPDiD6R9U4.
MaxQBiD6R9U4.
PaxDbiD6R9U4.
PeptideAtlasiD6R9U4.

Expressioni

Gene expression databases

BgeeiENSG00000145362.
ExpressionAtlasiD6R9U4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6R9U4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 177ANK_REP_REGIONInterPro annotationAdd BLAST133
Repeati78 – 110ANKPROSITE-ProRule annotationAdd BLAST33
Repeati111 – 143ANKPROSITE-ProRule annotationAdd BLAST33
Repeati144 – 176ANKPROSITE-ProRule annotationAdd BLAST33

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4177. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00840000129677.
HOGENOMiHOG000158359.
OMAiYSCRNGS.

Family and domain databases

CDDicd00204. ANK. 1 hit.
Gene3Di1.25.40.20. 2 hits.
InterProiView protein in InterPro
IPR030301. Ankyrin-B.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
PANTHERiPTHR24123:SF34. PTHR24123:SF34. 1 hit.
PfamiView protein in Pfam
PF12796. Ank_2. 2 hits.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 4 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.

Sequencei

Sequence statusi: Fragment.

D6R9U4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHAAASIKK VREADLDEKE KNLERDRKKQ RKIPRERMER KRKSDSNASF
60 70 80 90 100
LRAARAGNLD KVVEYLKGGI DINTCNQNGL NALHLAAKEG HVGLVQELLG
110 120 130 140 150
RGSSVDSATK KGNTALHIAS LAGQAEVVKV LVKEGANINA QSQNGFTPLY
160 170
MAAQENHIDV VKYLLENGAN QSTATED
Length:177
Mass (Da):19,301
Last modified:July 13, 2010 - v1
Checksum:i416EACEB4D6E513E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei177Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA. No translation available.
AC017007 Genomic DNA. No translation available.
AC093617 Genomic DNA. No translation available.
AC093879 Genomic DNA. No translation available.
AC093900 Genomic DNA. No translation available.
AC108042 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000508613; ENSP00000422900; ENSG00000145362.
UCSCiuc062zdf.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD6R9U4_HUMAN
AccessioniPrimary (citable) accession number: D6R9U4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: July 5, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported