ID   D6R9F7_HUMAN            Unreviewed;       156 AA.
AC   D6R9F7;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Mitogen-activated protein kinase binding protein 1 {ECO:0000313|Ensembl:ENSP00000422132.1};
DE   Flags: Fragment;
GN   Name=MAPKBP1 {ECO:0000313|Ensembl:ENSP00000422132.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000422132.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000422132.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M., Stewart S.,
RA   Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R.,
RA   Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0007829|PubMed:22814378}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA   Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA   Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA   Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT   "N-terminal acetylome analyses and functional insights of the N-terminal
RT   acetyltransferase NatB.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN   [3] {ECO:0000313|Ensembl:ENSP00000422132.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC020659; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC073657; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; D6R9F7; -.
DR   SMR; D6R9F7; -.
DR   IntAct; D6R9F7; 1.
DR   MassIVE; D6R9F7; -.
DR   MaxQB; D6R9F7; -.
DR   PeptideAtlas; D6R9F7; -.
DR   ProteomicsDB; 12998; -.
DR   Antibodypedia; 23379; 105 antibodies from 22 providers.
DR   Ensembl; ENST00000510535.1; ENSP00000422132.1; ENSG00000137802.14.
DR   UCSC; uc059iae.1; human.
DR   HGNC; HGNC:29536; MAPKBP1.
DR   VEuPathDB; HostDB:ENSG00000137802; -.
DR   GeneTree; ENSGT00940000160664; -.
DR   HOGENOM; CLU_1690751_0_0_1; -.
DR   OMA; TTTVAYC; -.
DR   ChiTaRS; MAPKBP1; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000137802; Expressed in right hemisphere of cerebellum and 169 other cell types or tissues.
DR   ExpressionAtlas; D6R9F7; baseline and differential.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR013979; TIF_beta_prop-like.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR44813; MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1; 1.
DR   PANTHER; PTHR44813:SF1; MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1; 1.
DR   Pfam; PF08662; eIF2A; 1.
DR   SMART; SM00320; WD40; 2.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:D6R9F7,
KW   ECO:0007829|MaxQB:D6R9F7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT   DOMAIN          72..151
FT                   /note="Translation initiation factor beta propellor-like"
FT                   /evidence="ECO:0000259|Pfam:PF08662"
FT   NON_TER         156
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000422132.1"
SQ   SEQUENCE   156 AA;  16937 MW;  8DD30D072C09DFCB CRC64;
     MAVEGSTITS RIKNLLRSPS IKLRRSKAGN RREDLSSKVT LEKVLGITVS GGRGLACDPR
     SGLVAYPAGC VVVLFNPRKH KQHHILNSSR KTITALAFSP DGKYLVTGES GHMPAVRVWD
     VAEHSQVAEL QEHKYGVACV AFSPSAKYIV SVGYQH
//