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Protein
Submitted name:

Alpha-L-iduronidase

Gene

IDUA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-L-iduronidaseImported
Gene namesi
Name:IDUAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:5391. IDUA.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000127415.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500308769520 – 224Sequence analysisAdd BLAST205

Proteomic databases

PeptideAtlasiD6R9D5.
PRIDEiD6R9D5.

Expressioni

Gene expression databases

BgeeiENSG00000127415.
ExpressionAtlasiD6R9D5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6R9D5.
SMRiD6R9D5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000015494.
HOGENOMiHOG000213960.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR000514. Glyco_hydro_39.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF01229. Glyco_hydro_39. 1 hit.
[Graphical view]
PRINTSiPR00745. GLHYDRLASE39.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS01027. GLYCOSYL_HYDROL_F39. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D6R9D5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPLRPRAAL LALLASLLAA PPVAPAEAPH LVHVDAARAL WPLRRFWRST
60 70 80 90 100
GFWGSTGRGL SYNFTHLDGY LDLLRENQLL PGFELMGSAS GHFTDFEDKQ
110 120 130 140 150
QVFEWKDLVS SLARRYIGRY GLAHVSKWNF ETWNEPDHHD FDNVSMTMQG
160 170 180 190 200
FLNYYDACSE GLRAASPALR LGGPGDSFHT PPRSPLSWGL LRHCHDGTNF
210 220
FTGEAGVRLD YISLHRKGAR SSIS
Length:224
Mass (Da):25,151
Last modified:July 13, 2010 - v1
Checksum:i714167B1A3F59714
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei224Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC019103 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000502910; ENSP00000422952; ENSG00000127415.
UCSCiuc062uhy.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC019103 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6R9D5.
SMRiD6R9D5.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiD6R9D5.
PRIDEiD6R9D5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000502910; ENSP00000422952; ENSG00000127415.
UCSCiuc062uhy.1. human.

Organism-specific databases

HGNCiHGNC:5391. IDUA.
OpenTargetsiENSG00000127415.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000015494.
HOGENOMiHOG000213960.

Miscellaneous databases

ChiTaRSiIDUA. human.

Gene expression databases

BgeeiENSG00000127415.
ExpressionAtlasiD6R9D5. baseline and differential.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR000514. Glyco_hydro_39.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF01229. Glyco_hydro_39. 1 hit.
[Graphical view]
PRINTSiPR00745. GLHYDRLASE39.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS01027. GLYCOSYL_HYDROL_F39. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD6R9D5_HUMAN
AccessioniPrimary (citable) accession number: D6R9D5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: November 2, 2016
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.