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Protein
Submitted name:

Transcription factor RelB

Gene

RELB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor RelBImported
Submitted name:
V-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (Avian)Imported
Gene namesi
Name:RELBImported
ORF Names:hCG_22137Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:9956. RELB.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104856.

PTM / Processingi

Proteomic databases

MaxQBiD6R992.
PeptideAtlasiD6R992.
PRIDEiD6R992.

Expressioni

Gene expression databases

BgeeiENSG00000104856.
ExpressionAtlasiD6R992. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000221452.

Structurei

3D structure databases

ProteinModelPortaliD6R992.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini119 – 296RHD (Rel-like)InterPro annotationAdd BLAST178

Sequence similaritiesi

Contains 1 RHD (Rel-like) domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IFBK. Eukaryota.
ENOG410ZMME. LUCA.
GeneTreeiENSGT00500000044765.
HOGENOMiHOG000148598.

Family and domain databases

CDDicd01177. IPT_NFkappaB. 1 hit.
Gene3Di2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProiIPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR033926. IPT_NFkappaB.
IPR000451. NFkB/Dor.
IPR008967. p53-like_TF_DNA-bd.
IPR030496. RelB.
IPR032399. RelB_leu_zip.
IPR032400. RelB_transact.
IPR030492. RHD_CS.
IPR032397. RHD_dimer.
IPR011539. RHD_DNA_bind_dom.
[Graphical view]
PANTHERiPTHR24169. PTHR24169. 1 hit.
PTHR24169:SF18. PTHR24169:SF18. 1 hit.
PfamiPF16180. RelB_leu_zip. 1 hit.
PF16181. RelB_transactiv. 1 hit.
PF16179. RHD_dimer. 1 hit.
PF00554. RHD_DNA_bind. 1 hit.
[Graphical view]
PRINTSiPR00057. NFKBTNSCPFCT.
SMARTiSM00429. IPT. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS01204. REL_1. 1 hit.
PS50254. REL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6R992-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRSGPASGP SVPTGRAMPS RRVARPPAAP ELGALGSPDL SSLSLAVSRS
60 70 80 90 100
TEIIDEYIKE NGFGLDGGQP GPGEGLPRLV SRGAASLSTV TLGPVAPPAT
110 120 130 140 150
PPPWGCPLGR LVSPAPGPGP QPHLVITEQP KQRGMRFRYE CEGRSAGSIL
160 170 180 190 200
GESSTEASKT LPAIELRDCG GLREVEVTAC LVWKDWPHRV HPHSLVGKDC
210 220 230 240 250
TDGICRVRLR PHVSPRHSFN NLGIQCVRKK EIEAAIERKI QLGIDPYNAG
260 270 280 290 300
SLKNHQEVDM NVVRICFQAS YRDQQGQMRR MDPVLSEPVY DKKSTNTSEL
310 320 330 340 350
RICRINKESG PCTGGEELYL LCDKVQKEDI SVVFSRASWE GRADFSQADV
360 370 380 390 400
HRQIAIVFKT PPYEDLEIVE PVTVNVFLQR LTDGVCSEPL PFTYLPRDHD
410 420 430 440 450
SYGVDKKRKR GMPDVLGELN SSDPHGIESK RRKKKPAILD HFLPNHGSGP
460 470 480 490 500
FLPPSALLPD PDFFSGTVSL PGLEPPGGPD LLDDGFAYDP TAPTLFTMLD
510 520 530 540 550
LLPPAPPHAS AVVCSGGAGA VVGETPGPEP LTLDSYQAPG PGDGGTASLV
560 570
GSNMFPNHYR EAAFGGGLLS PGPEAT
Length:576
Mass (Da):61,777
Last modified:July 13, 2010 - v1
Checksum:iB721A68364E6877F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011489 Genomic DNA. No translation available.
CH471126 Genomic DNA. Translation: EAW57316.1.
RefSeqiXP_005259184.1. XM_005259127.3.
UniGeneiHs.654402.

Genome annotation databases

EnsembliENST00000505236; ENSP00000423287; ENSG00000104856.
GeneIDi5971.
UCSCiuc060zvl.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011489 Genomic DNA. No translation available.
CH471126 Genomic DNA. Translation: EAW57316.1.
RefSeqiXP_005259184.1. XM_005259127.3.
UniGeneiHs.654402.

3D structure databases

ProteinModelPortaliD6R992.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000221452.

Proteomic databases

MaxQBiD6R992.
PeptideAtlasiD6R992.
PRIDEiD6R992.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000505236; ENSP00000423287; ENSG00000104856.
GeneIDi5971.
UCSCiuc060zvl.1. human.

Organism-specific databases

CTDi5971.
HGNCiHGNC:9956. RELB.
OpenTargetsiENSG00000104856.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFBK. Eukaryota.
ENOG410ZMME. LUCA.
GeneTreeiENSGT00500000044765.
HOGENOMiHOG000148598.

Miscellaneous databases

GenomeRNAii5971.

Gene expression databases

BgeeiENSG00000104856.
ExpressionAtlasiD6R992. baseline and differential.

Family and domain databases

CDDicd01177. IPT_NFkappaB. 1 hit.
Gene3Di2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProiIPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR033926. IPT_NFkappaB.
IPR000451. NFkB/Dor.
IPR008967. p53-like_TF_DNA-bd.
IPR030496. RelB.
IPR032399. RelB_leu_zip.
IPR032400. RelB_transact.
IPR030492. RHD_CS.
IPR032397. RHD_dimer.
IPR011539. RHD_DNA_bind_dom.
[Graphical view]
PANTHERiPTHR24169. PTHR24169. 1 hit.
PTHR24169:SF18. PTHR24169:SF18. 1 hit.
PfamiPF16180. RelB_leu_zip. 1 hit.
PF16181. RelB_transactiv. 1 hit.
PF16179. RHD_dimer. 1 hit.
PF00554. RHD_DNA_bind. 1 hit.
[Graphical view]
PRINTSiPR00057. NFKBTNSCPFCT.
SMARTiSM00429. IPT. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS01204. REL_1. 1 hit.
PS50254. REL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD6R992_HUMAN
AccessioniPrimary (citable) accession number: D6R992
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: November 30, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.