Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Ras GTPase-activating-like protein IQGAP2

Gene

IQGAP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Ras GTPase-activating-like protein IQGAP2Imported
Gene namesi
Name:IQGAP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000145703.15.
HGNCiHGNC:6111. IQGAP2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000145703.

PTM / Processingi

Proteomic databases

PaxDbiD6R939.
PeptideAtlasiD6R939.
PRIDEiD6R939.

Expressioni

Gene expression databases

BgeeiENSG00000145703.
ExpressionAtlasiD6R939. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6R939.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 129Calponin-homology (CH)InterPro annotationAdd BLAST116
Domaini567 – 600WWInterPro annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili138 – 165Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2128. Eukaryota.
COG5261. LUCA.
GeneTreeiENSGT00600000084379.
HOGENOMiHOG000004842.

Family and domain databases

CDDicd00014. CH. 1 hit.
cd00201. WW. 1 hit.
Gene3Di1.10.418.10. 1 hit.
InterProiView protein in InterPro
IPR036872. Calponin-like_dom_sf.
IPR001715. CH-domain.
IPR000048. IQ_motif_EF-hand-BS.
IPR001202. WW_dom.
PfamiView protein in Pfam
PF00307. CH. 1 hit.
PF00612. IQ. 3 hits.
SMARTiView protein in SMART
SM00033. CH. 1 hit.
SM00015. IQ. 3 hits.
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiView protein in PROSITE
PS50021. CH. 1 hit.
PS50096. IQ. 3 hits.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

D6R939-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDERRRQNIA YEYLCHLEEA KRWMEVCLVE ELPPTTELEE GLRNGVYLAK
60 70 80 90 100
LAKFFAPKMV SEKKIYDVEQ TRYKKSGLHF RHTDNTVQWL RAMESIGLPK
110 120 130 140 150
IFYPETTDVY DRKNIPRMIY CIHALSLYLF KLGIAPQIQD LLGKVDFTEE
160 170 180 190 200
EISNMRKELE KYGIQMPSFS KIGGILANEL SVDEAALHAA VIAINEAVEK
210 220 230 240 250
GIAEQTVVTL RNPNAVLTLV DDNLAPEYQK ELWDAKKKKE ENARLKNSCI
260 270 280 290 300
SEEERDAYEE LLTQAEIQGN INKVNRQAAV DHINAVIPEG DPENTLLALK
310 320 330 340 350
KPEAQLPAVY PFAAAMYQNE LFNLQKQNTM NYLAHEELLI AVEMLSAVAL
360 370 380 390 400
LNQALESNDL VSVQNQLRSP AIGLNNLDKA YVERYANTLL SVKLEVLSQG
410 420 430 440 450
QDNLSWNEIQ NCIDMVNAQI QEENDRVVAV GYINEAIDEG NPLRTLETLL
460 470 480 490 500
LPTANISDVD PAHAQHYQDV LYHAKSQKLG DSESVSKVLW LDEIQQAVDD
510 520 530 540 550
ANVDKDRAKQ WVTLVVDVNQ CLEGKKSSDI LSVLKSSTSN ANDIIPECAD
560 570 580 590 600
KYYDALVKAK ELKSERVSSD GSWLKLNLHK KYDYYYNTDS KESSWVTPES
610 620 630 640 650
CLYKESWLTG KEIEDIIEEV TVGYIRENIW SASEELLLRF QATSSGPILR
660 670 680 690 700
EEFEARKSFL HEQEENVVKI QAFWKGYKQR KEYMHRRQTF IDNTDSIVKI
710 720 730 740 750
QSWFRMATAR KSYLSRLQYF RDHNNEIVKI QSLLRANKAR DDYKTLVGSE
760 770 780 790 800
NPPLTVIRKF VYLLDQSDLD FQEELEVARL REEVVTKIRA NQQLEKDLNL
810 820
MDIKIGLLVK NRITLEDVIS HSKK
Length:824
Mass (Da):94,719
Last modified:October 5, 2016 - v8
Checksum:i2D37AB92290941FE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei824Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025188 Genomic DNA. No translation available.
AC026706 Genomic DNA. No translation available.
AC026725 Genomic DNA. No translation available.
AC093251 Genomic DNA. No translation available.
AC112173 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000514350; ENSP00000423672; ENSG00000145703.
UCSCiuc063erk.1. human.

Similar proteinsi

Entry informationi

Entry nameiD6R939_HUMAN
AccessioniPrimary (citable) accession number: D6R939
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: October 5, 2016
Last modified: October 25, 2017
This is version 57 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported