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Protein
Submitted name:

Intersectin 1 isoform A2

Gene

ITSN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. kinase activator activity Source: Ensembl

GO - Biological processi

  1. negative regulation of neuron apoptotic process Source: Ensembl
  2. positive regulation of protein kinase B signaling Source: Ensembl
  3. small GTPase mediated signal transduction Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Intersectin 1 isoform A2Imported
Gene namesi
Name:ITSN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. endocytic vesicle Source: Ensembl
  2. lamellipodium Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD6PAW2.
ExpressionAtlasiD6PAW2. baseline and differential.

Family & Domainsi

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D6PAW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGIASMPPL TAVAPVPMGS IPVVGMSPTL VSSVPTAAVP PLANGAPPVI
60 70 80 90 100
QPLPAFAHPA ATLPKSSSFS RSGPGSQLNT KLQKAQSFDV ASVPPVAEWA
110 120 130 140
VPQSSRLKYR QLFNSHDKTM SGHLTGPQAR TILMQSSLPQ A
Length:141
Mass (Da):14,500
Last modified:July 13, 2010 - v1
Checksum:iC7AA9E24189DA6C8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei141 – 1411Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU939621 mRNA. Translation: ADF97297.1.
UniGeneiHs.160324.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU939621 mRNA. Translation: ADF97297.1.
UniGeneiHs.160324.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

NextBioi35492712.

Gene expression databases

BgeeiD6PAW2.
ExpressionAtlasiD6PAW2. baseline and differential.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification and functional analysis of an alternative promoter of human intersectin 1 gene."
    Kropyvko S.V., Tsyba L.O., Skrypkina I.Y., Rynditch A.V.
    Biopolim. Kletka 26:115-120(2010)
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  2. Kropyvko S., Tsyba L., Rynditch A.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.

Entry informationi

Entry nameiD6PAW2_HUMAN
AccessioniPrimary (citable) accession number: D6PAW2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: March 4, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.