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Protein

Xylose isomerase

Gene

xylA

Organism
Bacteroides xylanisolvens XB1A
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei103 – 1031UniRule annotation
Active sitei106 – 1061UniRule annotation
Metal bindingi234 – 2341Magnesium 1UniRule annotation
Metal bindingi270 – 2701Magnesium 1UniRule annotation
Metal bindingi270 – 2701Magnesium 2UniRule annotation
Metal bindingi273 – 2731Magnesium 2UniRule annotation
Metal bindingi298 – 2981Magnesium 1UniRule annotation
Metal bindingi309 – 3091Magnesium 2UniRule annotation
Metal bindingi311 – 3111Magnesium 2UniRule annotation
Metal bindingi341 – 3411Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:BXY_06060Imported
OrganismiBacteroides xylanisolvens XB1AImported
Taxonomic identifieri657309 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000008795 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliD6D732.
SMRiD6D732. Positions 4-438.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6D732-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATKEFFPGI EKIKFEGKDS KNPMAFRYYD AEKVINGKKM KDWLRFAMAW
60 70 80 90 100
WHTLCAEGGD QFGGGTKQFP WNSNADAIQA AKDKMDAGFE FMQKMGIEYY
110 120 130 140 150
CFHDVDLVSE GASIEEYEAN LKAIVAYAKQ KQAETGIKLL WGTANVFGHA
160 170 180 190 200
RYMNGAATNP DFDVVARAAV QIKNAIDATI ELGGQNYVFW GGREGYMSLL
210 220 230 240 250
NTDQKREKEH LAKMLTIARD YARARGFKGT FLIEPKPMEP TKHQYDVDTE
260 270 280 290 300
TVIGFLKAHG LDKDFKVNIE VNHATLAGHT FEHELAVAVD NGMLGSIDAN
310 320 330 340 350
RGDYQNGWDT DQFPIDNYEL TQAMMQIIRN GGLGNGGTNF DAKTRRNSTD
360 370 380 390 400
LEDIFIAHIA GMDAMARALE SAAALLNESP YKKMLADRYA SFDGGKGKEF
410 420 430
EDGKLTLEDV VAYAKANGEP KQTSGKQELY EAILNMYC
Length:438
Mass (Da):48,891
Last modified:July 13, 2010 - v1
Checksum:i21E82BA66651997B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP929033 Genomic DNA. Translation: CBK65827.1.
RefSeqiYP_007791408.1. NC_021017.1.

Genome annotation databases

EnsemblBacteriaiCBK65827; CBK65827; BXY_06060.
GeneIDi15191066.
KEGGibxy:BXY_06060.
PATRICi42753683. VBIBacXyl109951_4168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP929033 Genomic DNA. Translation: CBK65827.1.
RefSeqiYP_007791408.1. NC_021017.1.

3D structure databases

ProteinModelPortaliD6D732.
SMRiD6D732. Positions 4-438.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBK65827; CBK65827; BXY_06060.
GeneIDi15191066.
KEGGibxy:BXY_06060.
PATRICi42753683. VBIBacXyl109951_4168.

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Bacteriodes xylanisolvens XB1A."
    metaHIT consortium -- http://www.metahit.eu/
    Pajon A., Turner K., Parkhill J., Bernalier A.
    Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: XB1AImported.
  2. Pajon A.
    Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: XB1AImported.

Entry informationi

Entry nameiD6D732_9BACE
AccessioniPrimary (citable) accession number: D6D732
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: April 29, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.