ID   D6D4V4_9BACE            Unreviewed;       386 AA.
AC   D6D4V4;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   ORFNames=BXY_44710 {ECO:0000313|EMBL:CBK69348.1};
OS   Bacteroides xylanisolvens XB1A.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=657309 {ECO:0000313|EMBL:CBK69348.1, ECO:0000313|Proteomes:UP000008795};
RN   [1] {ECO:0000313|EMBL:CBK69348.1, ECO:0000313|Proteomes:UP000008795}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=XB1A {ECO:0000313|EMBL:CBK69348.1,
RC   ECO:0000313|Proteomes:UP000008795};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Bernalier A.;
RT   "The genome sequence of Bacteriodes xylanisolvens XB1A.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBK69348.1, ECO:0000313|Proteomes:UP000008795}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=XB1A {ECO:0000313|EMBL:CBK69348.1,
RC   ECO:0000313|Proteomes:UP000008795};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FP929033; CBK69348.1; -; Genomic_DNA.
DR   RefSeq; WP_004314819.1; NC_021017.1.
DR   AlphaFoldDB; D6D4V4; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   KEGG; bxy:BXY_44710; -.
DR   PATRIC; fig|657309.4.peg.3456; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024620_1_0_10; -.
DR   Proteomes; UP000008795; Chromosome.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000313|EMBL:CBK69348.1};
KW   Hydrolase {ECO:0000313|EMBL:CBK69348.1};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..386
FT                   /note="exo-alpha-sialidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003082516"
FT   DOMAIN          71..362
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   386 AA;  42751 MW;  83527DB962E3ADF2 CRC64;
     MKTYKIITCV FLFTSMFTQA CQKDDETQGN PTPVPPEEEV PSSEFNYIYN QGTDGFELYR
     IPAIVKSKSN TLLAFAEARK ARSNGDSGDI DLVVKRSSDN GKTWSKQITI WNDGQNTCGN
     PVPIVDDRGR IHLLMTWNFQ TDKWGAITNG TGEDSRRPYY TYSDDDGITW AQPVEITSSV
     KKEKWDWYAT GPCHGIQIQK GIHKGRLVAP NYFTTRESGK VTSYSHIIYS DDYGKTWKPG
     EPTPVGGVGE CSVAEIGEGT LMLNMRADEG FYRKSCTSID GGLTWSSPQI SIDQIDCKCQ
     GSILSIGGAV FLSNAASATE RINMTIKKST DNGKNWKGQY TVYEGNSGYS DIVELSDSQI
     AIIYEGGEKR YTDGLAFKVV SIKSIQ
//