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D6CQK0

- D6CQK0_THIA3

UniProt

D6CQK0 - D6CQK0_THIA3

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Protein
Ribulose bisphosphate carboxylase large chain
Gene
rbcL, cbbL, THI_0135
Organism
Thiomonas arsenitoxydans (strain DSM 22701 / CIP 110005 / 3As)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site By similarity.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei116 – 1161Substrate; in homodimeric partner By similarityUniRule annotation
Binding sitei166 – 1661Substrate By similarityUniRule annotation
Active sitei168 – 1681Proton acceptor By similarityUniRule annotation
Binding sitei170 – 1701Substrate By similarityUniRule annotation
Metal bindingi194 – 1941Magnesium; via carbamate group By similarityUniRule annotation
Metal bindingi196 – 1961Magnesium By similarityUniRule annotation
Metal bindingi197 – 1971Magnesium By similarityUniRule annotation
Active sitei287 – 2871Proton acceptor By similarityUniRule annotation
Binding sitei288 – 2881Substrate By similarityUniRule annotation
Binding sitei320 – 3201Substrate By similarityUniRule annotation
Sitei327 – 3271Transition state stabilizer By similarityUniRule annotation
Binding sitei372 – 3721Substrate By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. monooxygenase activity Source: UniProtKB-KW
  3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. reductive pentose-phosphate cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Biological processi

Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciTARS426114-WGS:GSYJ-125-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylase large chainUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCO large subunitUniRule annotation
Gene namesi
Name:rbcLImported
Synonyms:cbbLUniRule annotation
Ordered Locus Names:THI_0135Imported
OrganismiThiomonas arsenitoxydans (strain DSM 22701 / CIP 110005 / 3As)Imported
Taxonomic identifieri426114 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesThiomonas
ProteomesiUP000002372: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei194 – 1941N6-carboxylysine By similarityUniRule annotation

Interactioni

Subunit structurei

Heterohexadecamer of 8 large chains and 8 small chains By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD6CQK0.
SMRiD6CQK0. Positions 16-460.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000230831.
KOiK01601.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPiMF_01338. RuBisCO_L_type1.
InterProiIPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6CQK0-1 [UniParc]FASTAAdd to Basket

« Hide

MAVKTYQAGV KEYRQTYWMP EYTPLDTDLL ACFKITPQAG VDREEAAAAV    50
AAESSTGTWT TVWTDLLTDM DYYKGRAYRI EDVPGDDTCF YAFIAYPIDL 100
FEEGSVVNVF TSLVGNVFGF KAIRALRLED IRFPIAYVKT CNGPPNGIQV 150
ERDVINKYGR PLLGCTIKPK LGLSGKNYGR AVYECLRGGL DFTKDDENIN 200
SQPFMRWKQR FDFVQEATLK AEQETGERKG HYLNVTAPTP DEMFKRAEYA 250
KEIGAPIIMH DYITGGFCAN TGLAQWCRDN GMLLHIHRAM HAVLDRNPHH 300
GIHFRVLTKI LRLSGGDHLH TGTVVGKLEG DRASTLGWID LLRESYVPED 350
RSRGIFFDQD WGSMPGAFAV ASGGIHVWHM PALVTIFGDD SVLQFGGGTL 400
GHPWGNAAGA AANRVALEAC VQARNEGRQV EKEGREILTA AAQHSPELKI 450
AMETWKEIKF EFDTVDKLDV TNK 473
Length:473
Mass (Da):52,787
Last modified:July 13, 2010 - v1
Checksum:i46EAF8F4C060ADF4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP475956 Genomic DNA. Translation: CAZ86891.1.
RefSeqiYP_003622759.1. NC_014145.1.

Genome annotation databases

EnsemblBacteriaiCAZ86891; CAZ86891; THI_0135.
GeneIDi13878401.
KEGGithi:THI_0135.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP475956 Genomic DNA. Translation: CAZ86891.1 .
RefSeqi YP_003622759.1. NC_014145.1.

3D structure databases

ProteinModelPortali D6CQK0.
SMRi D6CQK0. Positions 16-460.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAZ86891 ; CAZ86891 ; THI_0135 .
GeneIDi 13878401.
KEGGi thi:THI_0135.

Phylogenomic databases

HOGENOMi HOG000230831.
KOi K01601.

Enzyme and pathway databases

BioCyci TARS426114-WGS:GSYJ-125-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPi MF_01338. RuBisCO_L_type1.
InterProi IPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Genoscope - CEA
    Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 3As.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 22701 / CIP 110005 / 3As.

Entry informationi

Entry nameiD6CQK0_THIA3
AccessioniPrimary (citable) accession number: D6CQK0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: July 9, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel" By similarity.UniRule annotation

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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