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D5X0Y4 (D5X0Y4_THIK1) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:Tint_1393
OrganismThiomonas intermedia (strain K12) (Thiobacillus intermedius) [Complete proteome] [HAMAP]
Taxonomic identifier75379 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Thiomonas ›

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
D5X0Y4 [UniParc].

Last modified July 13, 2010. Version 1.
Checksum: 237F6E5BF8AC5893

FASTA41645,883
        10         20         30         40         50         60 
MDQHIRVPAG EKITVNPDFS LNVPDHPIIP YIEGDGTGFD ITPVMTKVVD AAVEKAYGGK 

        70         80         90        100        110        120 
RKIAWMEIFA GEKATRVYGP DVWLPEITLQ ILRDYVVSIK GPLTTPVGGG IRSLNVALRQ 

       130        140        150        160        170        180 
ELDLYVCLRP VRYFQGVPSP VKHPEKTDMV IFRENSEDIY AGIEWAAESE GAKKLVNFLI 

       190        200        210        220        230        240 
NEMGVKKIRF PDTSGIGIKP VSREGTERLV RKALQYAIDN DRKSVTLVHK GNIMKFTEGA 

       250        260        270        280        290        300 
FRDWGYGLAS KEFGAQLLDG GPWMRFKNPK TGREIVVKDM IADAFLQQIL LRPDEYDVIA 

       310        320        330        340        350        360 
TLNLNGDYVS DALAAQVGGI GIAPGANLSD SVAMFEATHG TAPKYAGKDY VNPGSEILSA 

       370        380        390        400        410 
EMMLRHMGWV EAADRIIASM EKSILSKQVT YDFARLLPDA TQVSCSGFGQ VMIDHM

« Hide

References

[1]"Complete sequence of Thiomonas intermedia K12."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Kerfeld C.A., Cannon G.C., Heinhorst S., Woyke T.
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 EMBL ADG30780.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002021 Genomic DNA. Translation: ADG30780.1.
RefSeqYP_003643110.1. NC_014153.1.

3D structure databases

ProteinModelPortalD5X0Y4.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADG30780; ADG30780; Tint_1393.
GeneID9152124.
KEGGtin:Tint_1393.
PATRIC38293314. VBIThiInt85915_1417.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5X0Y4_THIK1
AccessionPrimary (citable) accession number: D5X0Y4
Entry history
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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