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D5WES3

- D5WES3_BURSC

UniProt

D5WES3 - D5WES3_BURSC

Protein

Homoserine kinase

Gene

thrB

Organism
Burkholderia sp. (strain CCGE1002)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (13 Jul 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-homoserine = ADP + O-phospho-L-homoserine.UniRule annotationSAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. homoserine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. threonine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Threonine biosynthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBSP640511:GJ7J-5341-MONOMER.
    UniPathwayiUPA00050; UER00064.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Homoserine kinaseUniRule annotation (EC:2.7.1.39UniRule annotation)
    Short name:
    HKUniRule annotation
    Short name:
    HSKUniRule annotation
    Gene namesi
    Name:thrBUniRule annotation
    Ordered Locus Names:BC1002_5260Imported
    OrganismiBurkholderia sp. (strain CCGE1002)Imported
    Taxonomic identifieri640511 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
    ProteomesiUP000002190: Chromosome 2

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pseudomonas-type ThrB family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000004810.
    KOiK02204.

    Family and domain databases

    HAMAPiMF_00301. Homoser_kinase_2.
    InterProiIPR002575. Aminoglycoside_PTrfase.
    IPR005280. Homoserine_kinase_ThrB.
    IPR011009. Kinase-like_dom.
    [Graphical view]
    PfamiPF01636. APH. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    TIGRFAMsiTIGR00938. thrB_alt. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D5WES3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVFTAVNES QLAEWMSHYD LGDVVEFRGI SSGIENSNFF LTTTRGEYVL    50
    TIFEKLTAEQ LPFYLDLMRH LAAHRVPVPD PMPRLDGALF GMLLGKPATI 100
    VTKLEGAPEL APGVEHCAEV GHMLARMHLA GRDYPRYQPN LRSLPWWRET 150
    VPTILPYLEG EQRDLLASEL AHQEAFFASA DYAAMPSGPC HADLFRDNAM 200
    FAHAAPETGH EVRLGGFFDF YFAGCDKWLF DVAVTVNDWC VDLATGKLDT 250
    ERTEALLRAY QTVRPFTVEE NHHWGDMLRA GAYRFWVSRL YDFHLPRAAE 300
    LLKPHDPGHF ERILRERLLG VANPGIHTPC N 331
    Length:331
    Mass (Da):37,469
    Last modified:July 13, 2010 - v1
    Checksum:iB4164659358E14DF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002014 Genomic DNA. Translation: ADG19198.1.
    RefSeqiYP_003608709.1. NC_014118.1.

    Genome annotation databases

    EnsemblBacteriaiADG19198; ADG19198; BC1002_5260.
    GeneIDi9114575.
    KEGGibge:BC1002_5260.
    PATRICi37219602. VBIBurSp41388_5343.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002014 Genomic DNA. Translation: ADG19198.1 .
    RefSeqi YP_003608709.1. NC_014118.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADG19198 ; ADG19198 ; BC1002_5260 .
    GeneIDi 9114575.
    KEGGi bge:BC1002_5260.
    PATRICi 37219602. VBIBurSp41388_5343.

    Phylogenomic databases

    HOGENOMi HOG000004810.
    KOi K02204.

    Enzyme and pathway databases

    UniPathwayi UPA00050 ; UER00064 .
    BioCyci BSP640511:GJ7J-5341-MONOMER.

    Family and domain databases

    HAMAPi MF_00301. Homoser_kinase_2.
    InterProi IPR002575. Aminoglycoside_PTrfase.
    IPR005280. Homoserine_kinase_ThrB.
    IPR011009. Kinase-like_dom.
    [Graphical view ]
    Pfami PF01636. APH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    TIGRFAMsi TIGR00938. thrB_alt. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 2 of Burkholderia sp. CCGE1002."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R., Tiedje J.M., Woyke T.
      Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CCGE1002Imported.

    Entry informationi

    Entry nameiD5WES3_BURSC
    AccessioniPrimary (citable) accession number: D5WES3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3