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D5WES3

- D5WES3_BURSC

UniProt

D5WES3 - D5WES3_BURSC

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Protein

Homoserine kinase

Gene
thrB, BC1002_5260
Organism
Burkholderia sp. (strain CCGE1002)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-homoserine = ADP + O-phospho-L-homoserine.UniRule annotationSAAS annotations

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. homoserine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. threonine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Threonine biosynthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSP640511:GJ7J-5341-MONOMER.
UniPathwayiUPA00050; UER00064.

Names & Taxonomyi

Protein namesi
Recommended name:
Homoserine kinaseUniRule annotation (EC:2.7.1.39UniRule annotation)
Short name:
HKUniRule annotation
Short name:
HSKUniRule annotation
Gene namesi
Name:thrBUniRule annotation
Ordered Locus Names:BC1002_5260Imported
OrganismiBurkholderia sp. (strain CCGE1002)Imported
Taxonomic identifieri640511 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000002190: Chromosome 2

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudomonas-type ThrB family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000004810.
KOiK02204.

Family and domain databases

HAMAPiMF_00301. Homoser_kinase_2.
InterProiIPR002575. Aminoglycoside_PTrfase.
IPR005280. Homoserine_kinase_ThrB.
IPR011009. Kinase-like_dom.
[Graphical view]
PfamiPF01636. APH. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
TIGRFAMsiTIGR00938. thrB_alt. 1 hit.

Sequencei

Sequence statusi: Complete.

D5WES3-1 [UniParc]FASTAAdd to Basket

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MAVFTAVNES QLAEWMSHYD LGDVVEFRGI SSGIENSNFF LTTTRGEYVL    50
TIFEKLTAEQ LPFYLDLMRH LAAHRVPVPD PMPRLDGALF GMLLGKPATI 100
VTKLEGAPEL APGVEHCAEV GHMLARMHLA GRDYPRYQPN LRSLPWWRET 150
VPTILPYLEG EQRDLLASEL AHQEAFFASA DYAAMPSGPC HADLFRDNAM 200
FAHAAPETGH EVRLGGFFDF YFAGCDKWLF DVAVTVNDWC VDLATGKLDT 250
ERTEALLRAY QTVRPFTVEE NHHWGDMLRA GAYRFWVSRL YDFHLPRAAE 300
LLKPHDPGHF ERILRERLLG VANPGIHTPC N 331
Length:331
Mass (Da):37,469
Last modified:July 13, 2010 - v1
Checksum:iB4164659358E14DF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002014 Genomic DNA. Translation: ADG19198.1.
RefSeqiYP_003608709.1. NC_014118.1.

Genome annotation databases

EnsemblBacteriaiADG19198; ADG19198; BC1002_5260.
GeneIDi9114575.
KEGGibge:BC1002_5260.
PATRICi37219602. VBIBurSp41388_5343.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002014 Genomic DNA. Translation: ADG19198.1 .
RefSeqi YP_003608709.1. NC_014118.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADG19198 ; ADG19198 ; BC1002_5260 .
GeneIDi 9114575.
KEGGi bge:BC1002_5260.
PATRICi 37219602. VBIBurSp41388_5343.

Phylogenomic databases

HOGENOMi HOG000004810.
KOi K02204.

Enzyme and pathway databases

UniPathwayi UPA00050 ; UER00064 .
BioCyci BSP640511:GJ7J-5341-MONOMER.

Family and domain databases

HAMAPi MF_00301. Homoser_kinase_2.
InterProi IPR002575. Aminoglycoside_PTrfase.
IPR005280. Homoserine_kinase_ThrB.
IPR011009. Kinase-like_dom.
[Graphical view ]
Pfami PF01636. APH. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
TIGRFAMsi TIGR00938. thrB_alt. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 2 of Burkholderia sp. CCGE1002."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R., Tiedje J.M., Woyke T.
    Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCGE1002.

Entry informationi

Entry nameiD5WES3_BURSC
AccessioniPrimary (citable) accession number: D5WES3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: February 19, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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