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D5WES3

- D5WES3_BURSC

UniProt

D5WES3 - D5WES3_BURSC

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Protein

Homoserine kinase

Gene

thrB

Organism
Burkholderia sp. (strain CCGE1002)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-homoserine = ADP + O-phospho-L-homoserine.UniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. homoserine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. threonine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Threonine biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSP640511:GJ7J-5341-MONOMER.
UniPathwayiUPA00050; UER00064.

Names & Taxonomyi

Protein namesi
Recommended name:
Homoserine kinaseUniRule annotation (EC:2.7.1.39UniRule annotation)
Short name:
HKUniRule annotation
Short name:
HSKUniRule annotation
Gene namesi
Name:thrBUniRule annotation
Ordered Locus Names:BC1002_5260Imported
OrganismiBurkholderia sp. (strain CCGE1002)Imported
Taxonomic identifieri640511 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000002190: Chromosome 2

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudomonas-type ThrB family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000004810.
KOiK02204.

Family and domain databases

HAMAPiMF_00301. Homoser_kinase_2.
InterProiIPR002575. Aminoglycoside_PTrfase.
IPR005280. Homoserine_kinase_ThrB.
IPR011009. Kinase-like_dom.
[Graphical view]
PfamiPF01636. APH. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
TIGRFAMsiTIGR00938. thrB_alt. 1 hit.

Sequencei

Sequence statusi: Complete.

D5WES3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVFTAVNES QLAEWMSHYD LGDVVEFRGI SSGIENSNFF LTTTRGEYVL
60 70 80 90 100
TIFEKLTAEQ LPFYLDLMRH LAAHRVPVPD PMPRLDGALF GMLLGKPATI
110 120 130 140 150
VTKLEGAPEL APGVEHCAEV GHMLARMHLA GRDYPRYQPN LRSLPWWRET
160 170 180 190 200
VPTILPYLEG EQRDLLASEL AHQEAFFASA DYAAMPSGPC HADLFRDNAM
210 220 230 240 250
FAHAAPETGH EVRLGGFFDF YFAGCDKWLF DVAVTVNDWC VDLATGKLDT
260 270 280 290 300
ERTEALLRAY QTVRPFTVEE NHHWGDMLRA GAYRFWVSRL YDFHLPRAAE
310 320 330
LLKPHDPGHF ERILRERLLG VANPGIHTPC N
Length:331
Mass (Da):37,469
Last modified:July 13, 2010 - v1
Checksum:iB4164659358E14DF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002014 Genomic DNA. Translation: ADG19198.1.
RefSeqiYP_003608709.1. NC_014118.1.

Genome annotation databases

EnsemblBacteriaiADG19198; ADG19198; BC1002_5260.
GeneIDi9114575.
KEGGibge:BC1002_5260.
PATRICi37219602. VBIBurSp41388_5343.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002014 Genomic DNA. Translation: ADG19198.1 .
RefSeqi YP_003608709.1. NC_014118.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADG19198 ; ADG19198 ; BC1002_5260 .
GeneIDi 9114575.
KEGGi bge:BC1002_5260.
PATRICi 37219602. VBIBurSp41388_5343.

Phylogenomic databases

HOGENOMi HOG000004810.
KOi K02204.

Enzyme and pathway databases

UniPathwayi UPA00050 ; UER00064 .
BioCyci BSP640511:GJ7J-5341-MONOMER.

Family and domain databases

HAMAPi MF_00301. Homoser_kinase_2.
InterProi IPR002575. Aminoglycoside_PTrfase.
IPR005280. Homoserine_kinase_ThrB.
IPR011009. Kinase-like_dom.
[Graphical view ]
Pfami PF01636. APH. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
TIGRFAMsi TIGR00938. thrB_alt. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 2 of Burkholderia sp. CCGE1002."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R., Tiedje J.M., Woyke T.
    Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCGE1002Imported.

Entry informationi

Entry nameiD5WES3_BURSC
AccessioniPrimary (citable) accession number: D5WES3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 29, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3