D5WES3 (D5WES3_BURSC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Homoserine kinase HAMAP-Rule MF_00301
Short name=HK HAMAP-Rule MF_00301
Short name=HSK HAMAP-Rule MF_00301
EC=2.7.1.39 HAMAP-Rule MF_00301

Gene names

Name:	thrB HAMAP-Rule MF_00301
Ordered Locus Names:	BC1002_5260 EMBL ADG19198.1

Organism

Burkholderia sp. (strain CCGE1002) [Complete proteome] [HAMAP] EMBL ADG19198.1

Taxonomic identifier

640511 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP-Rule MF_00301 SAAS SAAS005280
Pathway	Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP-Rule MF_00301 SAAS SAAS005280
Sequence similarities	Belongs to the pseudomonas-type ThrB family. HAMAP-Rule MF_00301

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Threonine biosynthesis HAMAP-Rule MF_00301 SAAS SAAS005280
Ligand	ATP-binding HAMAP-Rule MF_00301 SAAS SAAS005280 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00301 SAAS SAAS005280 EMBL ADG19198.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	threonine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D5WES3 [UniParc]. Last modified July 13, 2010. Version 1. Checksum: B4164659358E14DF	FASTA	331	37,469
	10 20 30 40 50 60 MAVFTAVNES QLAEWMSHYD LGDVVEFRGI SSGIENSNFF LTTTRGEYVL TIFEKLTAEQ 70 80 90 100 110 120 LPFYLDLMRH LAAHRVPVPD PMPRLDGALF GMLLGKPATI VTKLEGAPEL APGVEHCAEV 130 140 150 160 170 180 GHMLARMHLA GRDYPRYQPN LRSLPWWRET VPTILPYLEG EQRDLLASEL AHQEAFFASA 190 200 210 220 230 240 DYAAMPSGPC HADLFRDNAM FAHAAPETGH EVRLGGFFDF YFAGCDKWLF DVAVTVNDWC 250 260 270 280 290 300 VDLATGKLDT ERTEALLRAY QTVRPFTVEE NHHWGDMLRA GAYRFWVSRL YDFHLPRAAE 310 320 330 LLKPHDPGHF ERILRERLLG VANPGIHTPC N

References

[1]

"Complete sequence of chromosome 2 of Burkholderia sp. CCGE1002." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R., Tiedje J.M., Woyke T. Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CCGE1002.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002014 Genomic DNA. Translation: ADG19198.1.
RefSeq	YP_003608709.1. NC_014118.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	9114575.
KEGG	bge:BC1002_5260.
PATRIC	37219602. VBIBurSp41388_5343.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000004810.
KO	K02204.
Enzyme and pathway databases
BioCyc	BSP640511:GJ7J-5341-MONOMER.
UniPathway	UPA00050; UER00064.
Family and domain databases
HAMAP	MF_00301. Homoser_kinase_2.
InterPro	IPR002575. Aminoglycoside_PTrfase. IPR005280. Homoserine_kinase_ThrB. IPR011009. Kinase-like_dom. [Graphical view]
Pfam	PF01636. APH. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
TIGRFAMs	TIGR00938. thrB_alt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

D5WES3_BURSC

Accession

Primary (citable) accession number: D5WES3

Entry history

Integrated into UniProtKB/TrEMBL:	July 13, 2010
Last sequence update:	July 13, 2010
Last modified:	May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)