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D5W8W2 (D5W8W2_BURSC) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site351Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2531Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1301Substrate By similarity HAMAP-Rule MF_01201
Binding site3011Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue351N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D5W8W2 [UniParc].

Last modified July 13, 2010. Version 1.
Checksum: 721254BDCBB308F7

FASTA35638,098
        10         20         30         40         50         60 
MPRPLSATIH TAALANNLAV ARRHAPKSKI WAVVKANAYG HGLARVFPGL RATDGFGLLD 

        70         80         90        100        110        120 
LEEAVKLREL GWAGPILLLE GFFRPTDIDV IDRYSLTTAL HSDEQLRMLE MARLSKPVNI 

       130        140        150        160        170        180 
QLKMNTGMNR LGYTVEKFRA AWERARACQG VGQITLMTHF SDADAERGIA HQMEAFERGA 

       190        200        210        220        230        240 
QGIAGARSLS NSAATLWHPE AHFDWVRPGI ILYGASPSGV TAAIDGTGLQ PAMTLASELI 

       250        260        270        280        290        300 
AVQTLGEGSS VGYGSTFTAR APMRIGVVAC GYADGYPRVA PEGTPVIVDG VRTRIVGRVS 

       310        320        330        340        350 
MDMLTVDLTP VPTANVGSRV ELWGTALPID NVAQACGTIG YELMCAVAPR VPVRAE 

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia sp. CCGE1002."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R., Tiedje J.M., Woyke T.
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CCGE1002 EMBL ADG15857.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002013 Genomic DNA. Translation: ADG15857.1.
RefSeqYP_003605368.1. NC_014117.1.

3D structure databases

ProteinModelPortalD5W8W2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADG15857; ADG15857; BC1002_1793.
GeneID9089478.
KEGGbge:BC1002_1793.
PATRIC37212457. VBIBurSp41388_1827.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031446.
KOK01775.

Enzyme and pathway databases

BioCycBSP640511:GJ7J-1817-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5W8W2_BURSC
AccessionPrimary (citable) accession number: D5W8W2
Entry history
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: February 19, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)