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D5W8V2 (D5W8V2_BURSC) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase HAMAP-Rule MF_00811
EC=2.3.1.117 HAMAP-Rule MF_00811
Alternative name(s):
Tetrahydrodipicolinate N-succinyltransferase HAMAP-Rule MF_00811
Gene names
Name:dapD HAMAP-Rule MF_00811
Ordered Locus Names:BC1002_1783 EMBL ADG15847.1
OrganismBurkholderia sp. (strain CCGE1002) [Complete proteome] [HAMAP] EMBL ADG15847.1
Taxonomic identifier640511 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate. HAMAP-Rule MF_00811 SAAS SAAS005664

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3. HAMAP-Rule MF_00811 SAAS SAAS005664

Subunit structure

Homotrimer By similarity. HAMAP-Rule MF_00811

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00811 SAAS SAAS005664.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. HAMAP-Rule MF_00811

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site1061Substrate By similarity HAMAP-Rule MF_00811
Binding site1431Substrate By similarity HAMAP-Rule MF_00811

Sequences

Sequence LengthMass (Da)Tools
D5W8V2 [UniParc].

Last modified July 13, 2010. Version 1.
Checksum: E5F978046672F53B

FASTA27529,458
        10         20         30         40         50         60 
MSQQLQSIID TAWDNRAELS PKAAPAEVRE AVAHAIEQLD KGALRVAEKK DGDWVVNQWL 

        70         80         90        100        110        120 
KKAVLLSFRL EDNAPMPAGG YSQFYDKVPS KFANYTAEDF AAGGFRVVPP AIARRGSFIA 

       130        140        150        160        170        180 
KNVVLMPSYT NIGAYVDEGT MVDTWATVGS CAQIGKNVHL SGGVGIGGVL EPLQANPVII 

       190        200        210        220        230        240 
EDNCFIGARS EVVEGVIVEE NSVISMGVYL GQSTKIYDRE TGEVTYGRIP AGSVVVAGNL 

       250        260        270 
PSKDGTHSLY CAVIVKKVDA KTRAKVGLNE LLRGD

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia sp. CCGE1002."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R., Tiedje J.M., Woyke T.
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CCGE1002 EMBL ADG15847.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002013 Genomic DNA. Translation: ADG15847.1.
RefSeqYP_003605358.1. NC_014117.1.

3D structure databases

ProteinModelPortalD5W8V2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID9089468.
KEGGbge:BC1002_1783.
PATRIC37212435. VBIBurSp41388_1816.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000003295.
KOK00674.

Enzyme and pathway databases

BioCycBSP640511:GJ7J-1807-MONOMER.
UniPathwayUPA00034; UER00019.

Family and domain databases

Gene3D1.10.166.10. 1 hit.
HAMAPMF_00811. DapD.
InterProIPR005664. DapD_Trfase_Hexpep_rpt_fam.
IPR001451. Hexapep_transf.
IPR018357. Hexapep_transf_CS.
IPR023180. THP_succinylTrfase_dom1.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PANTHERPTHR19136:SF52. PTHR19136:SF52. 1 hit.
PfamPF00132. Hexapep. 2 hits.
[Graphical view]
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR00965. dapD. 1 hit.
PROSITEPS00101. HEXAPEP_TRANSFERASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5W8V2_BURSC
AccessionPrimary (citable) accession number: D5W8V2
Entry history
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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