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D5W8D6

- D5W8D6_BURSC

UniProt

D5W8D6 - D5W8D6_BURSC

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Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Burkholderia sp. (strain CCGE1002)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei10 – 101NucleophileUniRule annotation
Metal bindingi10 – 101MagnesiumUniRule annotation
Metal bindingi12 – 121Magnesium; via carbonyl oxygenUniRule annotation
Active sitei51 – 511Schiff-base intermediate with substrateUniRule annotation
Metal bindingi184 – 1841MagnesiumUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphonoacetaldehyde hydrolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. organic phosphonate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation, Schiff baseUniRule annotation

Enzyme and pathway databases

BioCyciBSP640511:GJ7J-1636-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
Short name:
PhosphonataseUniRule annotation
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
Gene namesi
Name:phnXUniRule annotation
Ordered Locus Names:BC1002_1612Imported
OrganismiBurkholderia sp. (strain CCGE1002)Imported
Taxonomic identifieri640511 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000002190: Chromosome 1

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD5W8D6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000217971.
KOiK05306.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX.
InterProiIPR023214. HAD-like_dom.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

D5W8D6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKYVKAVIFD WAGTVVDYGS RAPMGAFVET FEQFGVPITI DEARGPMGMA
60 70 80 90 100
KRPHIAALMA LPRVAQAWAE RHGHTPTDAD IDAVYDVFVP KNIAVAASYS
110 120 130 140 150
AVIPGVAEVA SALRHDDIRI GTTTGYTREI IDEIVPGAAA QGFSPDSIVC
160 170 180 190 200
TGDTPEGRPS PYMIYRTLPQ LGVWRAKEAI KVDDTEVGIE EGINGGTWTV
210 220 230 240 250
GVAVSGNAFG MSEAEVKALP ADEFAARRNV ATARLKAAGA HYVIDSVADL
260
MPVVYDIDAR LARGERP
Length:267
Mass (Da):28,516
Last modified:July 13, 2010 - v1
Checksum:iDE63A3E26CA1B2DB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002013 Genomic DNA. Translation: ADG15681.1.
RefSeqiYP_003605192.1. NC_014117.1.

Genome annotation databases

EnsemblBacteriaiADG15681; ADG15681; BC1002_1612.
GeneIDi9089297.
KEGGibge:BC1002_1612.
PATRICi37212064. VBIBurSp41388_1631.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002013 Genomic DNA. Translation: ADG15681.1 .
RefSeqi YP_003605192.1. NC_014117.1.

3D structure databases

ProteinModelPortali D5W8D6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADG15681 ; ADG15681 ; BC1002_1612 .
GeneIDi 9089297.
KEGGi bge:BC1002_1612.
PATRICi 37212064. VBIBurSp41388_1631.

Phylogenomic databases

HOGENOMi HOG000217971.
KOi K05306.

Enzyme and pathway databases

BioCyci BSP640511:GJ7J-1636-MONOMER.

Family and domain databases

Gene3Di 1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPi MF_01375. PhnX.
InterProi IPR023214. HAD-like_dom.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view ]
Pfami PF13419. HAD_2. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01422. phosphonatase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia sp. CCGE1002."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R., Tiedje J.M., Woyke T.
    Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCGE1002Imported.

Entry informationi

Entry nameiD5W8D6_BURSC
AccessioniPrimary (citable) accession number: D5W8D6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 29, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3