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Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Burkholderia sp. (strain CCGE1002)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei10NucleophileUniRule annotation1
Metal bindingi10MagnesiumUniRule annotation1
Metal bindingi12Magnesium; via carbonyl oxygenUniRule annotation1
Active sitei51Schiff-base intermediate with substrateUniRule annotation1
Metal bindingi184MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationImported
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation, Schiff baseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
Short name:
PhosphonataseUniRule annotation
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
Gene namesi
Name:phnXUniRule annotation
Ordered Locus Names:BC1002_1612Imported
OrganismiBurkholderia sp. (strain CCGE1002)Imported
Taxonomic identifieri640511 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
Proteomesi
  • UP000002190 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi640511.BC1002_1612.

Structurei

3D structure databases

ProteinModelPortaliD5W8D6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 201HAD-like_domInterPro annotationAdd BLAST195

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108KAZ. Bacteria.
COG0637. LUCA.
HOGENOMiHOG000217971.
KOiK05306.
OMAiKAVIFDW.
OrthoDBiPOG091H05HY.

Family and domain databases

CDDicd02586. HAD_PHN. 1 hit.
Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 1 hit.
HAMAPiMF_01375. PhnX. 1 hit.
InterProiView protein in InterPro
IPR023214. HAD-like_dom.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
PfamiView protein in Pfam
PF13419. HAD_2. 1 hit.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

D5W8D6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYVKAVIFD WAGTVVDYGS RAPMGAFVET FEQFGVPITI DEARGPMGMA
60 70 80 90 100
KRPHIAALMA LPRVAQAWAE RHGHTPTDAD IDAVYDVFVP KNIAVAASYS
110 120 130 140 150
AVIPGVAEVA SALRHDDIRI GTTTGYTREI IDEIVPGAAA QGFSPDSIVC
160 170 180 190 200
TGDTPEGRPS PYMIYRTLPQ LGVWRAKEAI KVDDTEVGIE EGINGGTWTV
210 220 230 240 250
GVAVSGNAFG MSEAEVKALP ADEFAARRNV ATARLKAAGA HYVIDSVADL
260
MPVVYDIDAR LARGERP
Length:267
Mass (Da):28,516
Last modified:July 13, 2010 - v1
Checksum:iDE63A3E26CA1B2DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002013 Genomic DNA. Translation: ADG15681.1.
RefSeqiWP_013089551.1. NC_014117.1.

Genome annotation databases

EnsemblBacteriaiADG15681; ADG15681; BC1002_1612.
KEGGibge:BC1002_1612.

Similar proteinsi

Entry informationi

Entry nameiD5W8D6_BURSC
AccessioniPrimary (citable) accession number: D5W8D6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: September 27, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported