Skip Header

Contribute Send feedback
Read comments (?) or add your own

D5W8D6 (D5W8D6_BURSC) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphonoacetaldehyde hydrolase HAMAP-Rule MF_01375
Short name=Phosphonatase HAMAP-Rule MF_01375
EC=3.11.1.1 HAMAP-Rule MF_01375
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolase HAMAP-Rule MF_01375
Gene names
Name:phnX HAMAP-Rule MF_01375
Ordered Locus Names:BC1002_1612 EMBL ADG15681.1
OrganismBurkholderia sp. (strain CCGE1002) [Complete proteome] [HAMAP] EMBL ADG15681.1
Taxonomic identifier640511 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in phosphonate degradation By similarity. HAMAP-Rule MF_01375

Catalytic activity

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate. HAMAP-Rule MF_01375

Cofactor

Binds 1 Mg2+ ion per subunit By similarity. HAMAP-Rule MF_01375

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01375

Sequence similarities

Belongs to the HAD-like hydrolase superfamily. PhnX family. HAMAP-Rule MF_01375

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site101Nucleophile By similarity HAMAP-Rule MF_01375
Active site511Schiff-base intermediate with substrate By similarity HAMAP-Rule MF_01375
Metal binding101Magnesium By similarity HAMAP-Rule MF_01375
Metal binding121Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_01375
Metal binding1841Magnesium By similarity HAMAP-Rule MF_01375

Sequences

Sequence LengthMass (Da)Tools
D5W8D6 [UniParc].

Last modified July 13, 2010. Version 1.
Checksum: DE63A3E26CA1B2DB

FASTA26728,516
        10         20         30         40         50         60 
MKYVKAVIFD WAGTVVDYGS RAPMGAFVET FEQFGVPITI DEARGPMGMA KRPHIAALMA 

        70         80         90        100        110        120 
LPRVAQAWAE RHGHTPTDAD IDAVYDVFVP KNIAVAASYS AVIPGVAEVA SALRHDDIRI 

       130        140        150        160        170        180 
GTTTGYTREI IDEIVPGAAA QGFSPDSIVC TGDTPEGRPS PYMIYRTLPQ LGVWRAKEAI 

       190        200        210        220        230        240 
KVDDTEVGIE EGINGGTWTV GVAVSGNAFG MSEAEVKALP ADEFAARRNV ATARLKAAGA 

       250        260 
HYVIDSVADL MPVVYDIDAR LARGERP

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia sp. CCGE1002."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R., Tiedje J.M., Woyke T.
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CCGE1002 EMBL ADG15681.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002013 Genomic DNA. Translation: ADG15681.1.
RefSeqYP_003605192.1. NC_014117.1.

3D structure databases

ProteinModelPortalD5W8D6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID9089297.
KEGGbge:BC1002_1612.
PATRIC37212064. VBIBurSp41388_1631.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000217971.
KOK05306.

Enzyme and pathway databases

BioCycBSP640511:GJ7J-1636-MONOMER.

Family and domain databases

Gene3D1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPMF_01375. PhnX.
InterProIPR023214. HAD-like_dom.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMSSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01422. phosphonatase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD5W8D6_BURSC
AccessionPrimary (citable) accession number: D5W8D6
Entry history
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info