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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia sp. (strain CCGE1002)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei282UniRule annotation1
Active sitei724UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBSP640511:G1GLK-778-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:BC1002_0773Imported
OrganismiBurkholderia sp. (strain CCGE1002)Imported
Taxonomic identifieri640511 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
Proteomesi
  • UP000002190 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi640511.BC1002_0773

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

D5W4Q5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSGSARPA RRNTASPTAR PADAAAPDVL SDAAAHGRSS SVADQRAKRR
60 70 80 90 100
AIAAQAAKAS KASQTTVPVK QDKAQKAPKA GKAEKAATSA TASKPAKVKI
110 120 130 140 150
KVDGDATPPR AAKAERLEAM PQAESAAAPT VKNGGGRTRE DKDHPLFQDI
160 170 180 190 200
RYLGRLLGDV LREQEGDAVF DVVETIRQNA VRFRREDDSA AAQTLDKKLR
210 220 230 240 250
SLTPEQTVSV VRAFSYFSHL ANIAEDRHRN RRHRIHALAG SASQPGTIAH
260 270 280 290 300
ALERLVAAGA AATPVLQRFF DDALIMPVLT AHPTEVQRKS ILDAQHDIAR
310 320 330 340 350
LLAERDQPLT NRERAHNEAM LRARVTSLWQ TRMLRDARLT VADEIENALS
360 370 380 390 400
YYRSTFLEEL PALYADIEEA LKEHGLEARL PPFFQMGSWI GGDRDGNPNV
410 420 430 440 450
TAETLENAIT RQAAVIFEHY LVQVHKLGEE LSMSNVLVGV SDALNELADI
460 470 480 490 500
SPDHSPHRTD EPYRRALIGI YTRLAASARV RLGEGSVPLR SAGRGVAPIR
510 520 530 540 550
ATPYDDAADF VRDLHVLIDS LAEHHGAPLA APRLAPLARA AEVFGFHLAS
560 570 580 590 600
IDLRQSSDIH EAVIAELLKR AGVEDDYAGL SEANKLKVLL AELAQPRALR
610 620 630 640 650
VPYAEYSDLV KSELAVLEEA RITREKFGAR AVRNYIISHT ETVSDLVEVM
660 670 680 690 700
LLQKETGLLL GHLGDEHDPA RASLMVIPLF ETIPDLRNAP HIMRDLIALP
710 720 730 740 750
GIGALIEHQG NEQEVMLGYS DSNKDGGFLT SNWELYRAEL ALVSLFNERG
760 770 780 790 800
VTLRLFHGRG GTVGRGGGPT YQAILSQPPG TVAGQIRLTE QGEVIASKFA
810 820 830 840 850
NPEIGRRNLE TVVAATLEAS LLPHDHTLAE LPVYEETMQQ LSDTAMAAYR
860 870 880 890 900
ALVYETPGFK EYFFESTPIA EIAELNIGSR PASRKLQDPK QRKIEDLRAI
910 920 930 940 950
PWGFSWGQCR LLLTGWYGFG SAVTEHLDSA PSDAERARRL ALLKKMHKSW
960 970 980 990 1000
PFFANLMSNM DMVIAKTDLA VASRYAALVT DKKLRKHVFE RIVAEWERTS
1010 1020 1030 1040 1050
KVLSEITGKS ERLAENPLLA RSIKNRFPYL DPLNHLQVEL LKRYRAGDTN
1060 1070
ARVRRGIHLC INGIAAGLRN TG
Length:1,072
Mass (Da):117,851
Last modified:July 13, 2010 - v1
Checksum:iA976EF9514FAC546
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002013 Genomic DNA Translation: ADG14870.1
RefSeqiWP_013088759.1, NC_014117.1

Genome annotation databases

EnsemblBacteriaiADG14870; ADG14870; BC1002_0773
KEGGibge:BC1002_0773

Similar proteinsi

Entry informationi

Entry nameiD5W4Q5_BURSC
AccessioniPrimary (citable) accession number: D5W4Q5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: March 28, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health