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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia sp. (strain CCGE1002)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei282 – 2821UniRule annotation
Active sitei724 – 7241UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBSP640511:GJ7J-781-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:BC1002_0773Imported
OrganismiBurkholderia sp. (strain CCGE1002)Imported
Taxonomic identifieri640511 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000002190 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5W4Q5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSGSARPA RRNTASPTAR PADAAAPDVL SDAAAHGRSS SVADQRAKRR
60 70 80 90 100
AIAAQAAKAS KASQTTVPVK QDKAQKAPKA GKAEKAATSA TASKPAKVKI
110 120 130 140 150
KVDGDATPPR AAKAERLEAM PQAESAAAPT VKNGGGRTRE DKDHPLFQDI
160 170 180 190 200
RYLGRLLGDV LREQEGDAVF DVVETIRQNA VRFRREDDSA AAQTLDKKLR
210 220 230 240 250
SLTPEQTVSV VRAFSYFSHL ANIAEDRHRN RRHRIHALAG SASQPGTIAH
260 270 280 290 300
ALERLVAAGA AATPVLQRFF DDALIMPVLT AHPTEVQRKS ILDAQHDIAR
310 320 330 340 350
LLAERDQPLT NRERAHNEAM LRARVTSLWQ TRMLRDARLT VADEIENALS
360 370 380 390 400
YYRSTFLEEL PALYADIEEA LKEHGLEARL PPFFQMGSWI GGDRDGNPNV
410 420 430 440 450
TAETLENAIT RQAAVIFEHY LVQVHKLGEE LSMSNVLVGV SDALNELADI
460 470 480 490 500
SPDHSPHRTD EPYRRALIGI YTRLAASARV RLGEGSVPLR SAGRGVAPIR
510 520 530 540 550
ATPYDDAADF VRDLHVLIDS LAEHHGAPLA APRLAPLARA AEVFGFHLAS
560 570 580 590 600
IDLRQSSDIH EAVIAELLKR AGVEDDYAGL SEANKLKVLL AELAQPRALR
610 620 630 640 650
VPYAEYSDLV KSELAVLEEA RITREKFGAR AVRNYIISHT ETVSDLVEVM
660 670 680 690 700
LLQKETGLLL GHLGDEHDPA RASLMVIPLF ETIPDLRNAP HIMRDLIALP
710 720 730 740 750
GIGALIEHQG NEQEVMLGYS DSNKDGGFLT SNWELYRAEL ALVSLFNERG
760 770 780 790 800
VTLRLFHGRG GTVGRGGGPT YQAILSQPPG TVAGQIRLTE QGEVIASKFA
810 820 830 840 850
NPEIGRRNLE TVVAATLEAS LLPHDHTLAE LPVYEETMQQ LSDTAMAAYR
860 870 880 890 900
ALVYETPGFK EYFFESTPIA EIAELNIGSR PASRKLQDPK QRKIEDLRAI
910 920 930 940 950
PWGFSWGQCR LLLTGWYGFG SAVTEHLDSA PSDAERARRL ALLKKMHKSW
960 970 980 990 1000
PFFANLMSNM DMVIAKTDLA VASRYAALVT DKKLRKHVFE RIVAEWERTS
1010 1020 1030 1040 1050
KVLSEITGKS ERLAENPLLA RSIKNRFPYL DPLNHLQVEL LKRYRAGDTN
1060 1070
ARVRRGIHLC INGIAAGLRN TG
Length:1,072
Mass (Da):117,851
Last modified:July 13, 2010 - v1
Checksum:iA976EF9514FAC546
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002013 Genomic DNA. Translation: ADG14870.1.
RefSeqiWP_013088759.1. NC_014117.1.
YP_003604381.1. NC_014117.1.

Genome annotation databases

EnsemblBacteriaiADG14870; ADG14870; BC1002_0773.
KEGGibge:BC1002_0773.
PATRICi37210284. VBIBurSp41388_0756.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002013 Genomic DNA. Translation: ADG14870.1.
RefSeqiWP_013088759.1. NC_014117.1.
YP_003604381.1. NC_014117.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADG14870; ADG14870; BC1002_0773.
KEGGibge:BC1002_0773.
PATRICi37210284. VBIBurSp41388_0756.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.

Enzyme and pathway databases

BioCyciBSP640511:GJ7J-781-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia sp. CCGE1002."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R., Tiedje J.M., Woyke T.
    Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCGE1002Imported.

Entry informationi

Entry nameiD5W4Q5_BURSC
AccessioniPrimary (citable) accession number: D5W4Q5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: April 29, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.