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D5VUB0 (RIBL_METIM) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FAD synthase

EC=2.7.7.2
Alternative name(s):
FMN adenylyltransferase
Flavin adenine dinucleotide synthase
Gene names
Name:ribL
Ordered Locus Names:Metin_0050
OrganismMethanocaldococcus infernus (strain DSM 11812 / JCM 15783 / ME) [Complete proteome] [HAMAP]
Taxonomic identifier573063 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length145 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme By similarity. HAMAP-Rule MF_02115

Catalytic activity

ATP + FMN = diphosphate + FAD. HAMAP-Rule MF_02115

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_02115

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1. HAMAP-Rule MF_02115

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02115

Sequence similarities

Belongs to the archaeal FAD synthase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 145145FAD synthase HAMAP-Rule MF_02115
PRO_0000406248

Regions

Nucleotide binding9 – 102ATP By similarity
Nucleotide binding14 – 174ATP By similarity
Nucleotide binding92 – 954ATP By similarity

Sites

Binding site1221ATP; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
D5VUB0 [UniParc].

Last modified July 13, 2010. Version 1.
Checksum: 0C7C2D7DBEB02383

FASTA14516,745
        10         20         30         40         50         60 
MKRVVAAGTF DILHPGHYEF LKFAKSLGDE LIVIVARDKT VEKIKGRKPI IPEEQRRAMV 

        70         80         90        100        110        120 
EALKPVDKAI LGSLNNKLEP IIELKPDIIV LGPDQRTFDE EELKRELKKY DLSPKIVRFN 

       130        140 
KYIKCPFHSS YDIVKEILKR YGGKE 

« Hide

References

[1]"Complete sequence of Methanocaldococcus infernus ME."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Woyke T.
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 11812 / JCM 15783 / ME.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002009 Genomic DNA. Translation: ADG12722.1.
RefSeqYP_003615686.1. NC_014122.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADG12722; ADG12722; Metin_0050.
GeneID9131049.
KEGGmif:Metin_0050.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000284153.
KOK14656.
OMAKKCPFHS.

Enzyme and pathway databases

BioCycMINF573063:GHL3-51-MONOMER.
UniPathwayUPA00277; UER00407.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_02115. FAD_synth_arch.
InterProIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBL_METIM
AccessionPrimary (citable) accession number: D5VUB0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: July 13, 2010
Last modified: February 19, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways