Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D5VSH2

- D5VSH2_METIM

UniProt

D5VSH2 - D5VSH2_METIM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable thymidylate kinase

Gene

tmk

Organism
Methanocaldococcus infernus (strain DSM 11812 / JCM 15783 / ME)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + dTMP = ADP + dTDP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi7 – 148ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidylate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dTDP biosynthetic process Source: InterPro
  2. dTTP biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

Nucleotide biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMINF573063:GHL3-877-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable thymidylate kinaseUniRule annotation (EC:2.7.4.9UniRule annotation)
Alternative name(s):
dTMP kinaseUniRule annotation
Gene namesi
Name:tmkUniRule annotation
Ordered Locus Names:Metin_0861Imported
OrganismiMethanocaldococcus infernus (strain DSM 11812 / JCM 15783 / ME)Imported
Taxonomic identifieri573063 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000002061: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidylate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229077.
KOiK00943.
OMAiYVYSSIV.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00165. Thymidylate_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR018095. Thymidylate_kin_CS.
IPR018094. Thymidylate_kinase.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00041. DTMP_kinase. 1 hit.
PROSITEiPS01331. THYMIDYLATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5VSH2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFIVFEGIDG SGKTTLSKML AKELSGYWTC EPTDGEIGRL IRSYLSSGNI
60 70 80 90 100
DNISLSLLFA ADRVEHCKEI EKVLNSGRDV ICDRYLYSSI AYQSSLGVEE
110 120 130 140 150
NFLWEINKYA IKPDLVFLLV VDVDEAMKRV KGKDIFENKN FLEKVQEKYL
160 170 180
ELAKRFNFIV IDTTNISIEE AYNKVRVKVY ECKC
Length:184
Mass (Da):21,139
Last modified:July 13, 2010 - v1
Checksum:i50F61AE87095A13D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002009 Genomic DNA. Translation: ADG13525.1.
RefSeqiYP_003616489.1. NC_014122.1.

Genome annotation databases

EnsemblBacteriaiADG13525; ADG13525; Metin_0861.
GeneIDi9131875.
KEGGimif:Metin_0861.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002009 Genomic DNA. Translation: ADG13525.1 .
RefSeqi YP_003616489.1. NC_014122.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADG13525 ; ADG13525 ; Metin_0861 .
GeneIDi 9131875.
KEGGi mif:Metin_0861.

Phylogenomic databases

HOGENOMi HOG000229077.
KOi K00943.
OMAi YVYSSIV.

Enzyme and pathway databases

BioCyci MINF573063:GHL3-877-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00165. Thymidylate_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR018095. Thymidylate_kin_CS.
IPR018094. Thymidylate_kinase.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00041. DTMP_kinase. 1 hit.
PROSITEi PS01331. THYMIDYLATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Methanocaldococcus infernus ME."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Woyke T.
    Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 11812 / JCM 15783 / MEImported.

Entry informationi

Entry nameiD5VSH2_METIM
AccessioniPrimary (citable) accession number: D5VSH2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 1, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3