D5VSH2 (D5VSH2_METIM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable thymidylate kinase HAMAP-Rule MF_00165
EC=2.7.4.9 HAMAP-Rule MF_00165

Alternative name(s):
dTMP kinase HAMAP-Rule MF_00165

Gene names

Name:	tmk HAMAP-Rule MF_00165
Ordered Locus Names:	Metin_0861

Organism

Methanocaldococcus infernus (strain DSM 11812 / JCM 15783 / ME) [Complete proteome] [HAMAP]

Taxonomic identifier

573063 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › Methanocaldococcus infernus

Protein attributes

Sequence length	184 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + dTMP = ADP + dTDP. HAMAP-Rule MF_00165
Sequence similarities	Belongs to the thymidylate kinase family. HAMAP-Rule MF_00165

Ontologies

Keywords
Biological process	Nucleotide biosynthesis HAMAP-Rule MF_00165
Ligand	ATP-binding HAMAP-Rule MF_00165 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00165 EMBL ADG13525.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dTDP biosynthetic process Inferred from electronic annotation. Source: InterPro dTTP biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP thymidylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	7 – 14	8	ATP By similarity HAMAP-Rule MF_00165

Sequences

	Sequence		Length	Mass (Da)
	D5VSH2 [UniParc]. Last modified July 13, 2010. Version 1. Checksum: 50F61AE87095A13D	FASTA	184	21,139
	10 20 30 40 50 60 MFIVFEGIDG SGKTTLSKML AKELSGYWTC EPTDGEIGRL IRSYLSSGNI DNISLSLLFA 70 80 90 100 110 120 ADRVEHCKEI EKVLNSGRDV ICDRYLYSSI AYQSSLGVEE NFLWEINKYA IKPDLVFLLV 130 140 150 160 170 180 VDVDEAMKRV KGKDIFENKN FLEKVQEKYL ELAKRFNFIV IDTTNISIEE AYNKVRVKVY ECKC

References

[1]

"Complete sequence of Methanocaldococcus infernus ME." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Woyke T. Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 11812 / JCM 15783 / ME.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002009 Genomic DNA. Translation: ADG13525.1.
RefSeq	YP_003616489.1. NC_014122.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADG13525; ADG13525; Metin_0861.
GeneID	9131875.
KEGG	mif:Metin_0861.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000229077.
KO	K00943.
OMA	YLYSSIA.
Enzyme and pathway databases
BioCyc	MINF573063:GHL3-877-MONOMER.
Family and domain databases
HAMAP	MF_00165. Thymidylate_kinase.
InterPro	IPR018095. Thymidylate_kin_CS. IPR018094. Thymidylate_kinase. [Graphical view]
PANTHER	PTHR10344. PTHR10344. 1 hit.
TIGRFAMs	TIGR00041. DTMP_kinase. 1 hit.
PROSITE	PS01331. THYMIDYLATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D5VSH2_METIM

Accession

Primary (citable) accession number: D5VSH2

Entry history

Integrated into UniProtKB/TrEMBL:	July 13, 2010
Last sequence update:	July 13, 2010
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)