Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA ligase

Gene

Tpau_3810

Organism
Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) (Corynebacterium paurometabolum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAU521096:GI2W-3851-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Tpau_3810Imported
OrganismiTsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) (Corynebacterium paurometabolum)Imported
Taxonomic identifieri521096 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeTsukamurellaceaeTsukamurella
ProteomesiUP000001213 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036008.
KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5UYT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMAGSLRRQR CPSALSSAYA AVVGPLRHNQ EVLFADVVAA STEVGATRAR
60 70 80 90 100
TAKIAALTRL LRDADAADVR PVVAWLSGSL LQERLGTGWR GVAKILDEQV
110 120 130 140 150
AAATPSLTVA DVSSAFDELA GTAGAGSVAR RGELLGALFG RATADEQRLL
160 170 180 190 200
VGLITGEVRH GALAGVMTDA VAHAAGVPLA TVRRAAMLSG SLPQTASAAL
210 220 230 240 250
AGGADALAGF GLEVLRGVSP MLASPADDLP AALADLGPEV SVEFKLDGAR
260 270 280 290 300
IQVHRNGDAV RVYTRTLRDI TDAVPEIVET AMALPCTSVV LDGESLALTD
310 320 330 340 350
AGRPRPFQET MSRFGSAGSM EDERSVLRPF FFDCLHLDGR DLLDEPLSAR
360 370 380 390 400
LAALEQVAGD LRIPALTRPS VEQASAHLEA ALAAGHEGVM VKGLDSPYAA
410 420 430 440 450
GRRGRAWQKV KQSYTLDLVV LGAEWGYGRR TGLLSNLHLG ARDPDGGEPI
460 470 480 490 500
MVGKTFKGLT DALLRWQTEE FPRHERQRSE HTVYLRPEIV VEIELDGVQR
510 520 530
SRRYPGGVAL RFARVLRYRP DKTAAEADTI DAVRALLPG
Length:539
Mass (Da):57,196
Last modified:July 13, 2010 - v1
Checksum:i0EE1885C9BC8E7D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001966 Genomic DNA. Translation: ADG80387.1.
RefSeqiYP_003648726.1. NC_014158.1.

Genome annotation databases

EnsemblBacteriaiADG80387; ADG80387; Tpau_3810.
KEGGitpr:Tpau_3810.
PATRICi38310977. VBITsuPau718_3817.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001966 Genomic DNA. Translation: ADG80387.1.
RefSeqiYP_003648726.1. NC_014158.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADG80387; ADG80387; Tpau_3810.
KEGGitpr:Tpau_3810.
PATRICi38310977. VBITsuPau718_3817.

Phylogenomic databases

HOGENOMiHOG000036008.
KOiK10747.

Enzyme and pathway databases

BioCyciTPAU521096:GI2W-3851-MONOMER.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040Imported.

Entry informationi

Entry nameiD5UYT4_TSUPD
AccessioniPrimary (citable) accession number: D5UYT4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: April 1, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.