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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) (Corynebacterium paurometabolum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei146UniRule annotation1
Active sitei583UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciTPAU521096:G1GKO-2518-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Tpau_2536Imported
OrganismiTsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) (Corynebacterium paurometabolum)Imported
Taxonomic identifieri521096 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesTsukamurellaceaeTsukamurella
Proteomesi
  • UP000001213 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi521096.Tpau_2536

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili277 – 297Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

D5URT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSEPARAAT EPLRDDIRLL GGILGDTVRE QAGERIFDLV ENARQESFRV
60 70 80 90 100
RRSEIDREQL AAMFTDLPTA EAVPVIRALS HFALLANLAE DLHRERRRAI
110 120 130 140 150
HVRAGEAPQA SSLAHTYTLL EDAGLDGDAV RAALRHALVV PVITAHPTET
160 170 180 190 200
RRRTVFDTQH RITELMRYRD RTQLDPREEE QVQVNLRRQI LTLWDTALVR
210 220 230 240 250
LERLRIQDEV VNGLRYFDAA FLEVMPQINH EIRTRLRELY PGTGLLSEPI
260 270 280 290 300
LRPGSWIGGD RDGNPYVTGE VVTMASRRAA ATALEHYLRQ LLELEKELAL
310 320 330 340 350
SLRLTTVSDE LLALAEWDTS PKQADEPYRR ALRWIRGRLS TTAADLLDEP
360 370 380 390 400
LDAGIDIDAP RYGGPSELLA DLAVVDASLR TAGDGLIADA RLQDLREALN
410 420 430 440 450
TFGFHLSGLD MRQNSDVHEE TISELFAWAG VHPDYASLDE SDRVRLLTDE
460 470 480 490 500
LRLRRPLVGP GAEFTEQTAK ELGVLHAAAD AVANLGPGAV PNYIISMCTS
510 520 530 540 550
VSDLLEAAVL LKEAGLLRPG DGSAADAVAT CSVNIVPLFE TIEDLQQGAA
560 570 580 590 600
TMRAAFEVPV YRSLVDGKGG LQEIMLGYSD SNKDGGYLAA NWALYRAELD
610 620 630 640 650
LVAMARDAGV TLRLFHGRGG TVGRGGGPSY DAILAQPPGA VRGTLRLTEQ
660 670 680 690 700
GEIIAAKYAE PALATRNLES LLAATLESTL LDVEGLGDDA EEAYAVLDEL
710 720 730 740 750
AALAREAYGD LVHRTDGFVE YFTTSTPVEE IGSLNIGSRP SSRKQTSKIS
760 770 780 790 800
DLRAIPWVMA WSLSRVMLPG FYGTGAAIEK WIDGGPSRLE QLRALYRRWP
810 820 830 840 850
FFQTVLSNMA QVLAKSDLGL AARYAELVPD AALRERVFGK IADEHRRTIE
860 870 880 890 900
MYYAIAETDD LLADNPALKR SVFNRFPYLE PLNHLQVELL RRYRAGDTDP
910 920
QVQRGILLTM NGLATALRNS G
Length:921
Mass (Da):101,575
Last modified:July 13, 2010 - v1
Checksum:i15A20D28394A927C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001966 Genomic DNA Translation: ADG79139.1
RefSeqiWP_013127158.1, NC_014158.1

Genome annotation databases

EnsemblBacteriaiADG79139; ADG79139; Tpau_2536
KEGGitpr:Tpau_2536

Similar proteinsi

Entry informationi

Entry nameiD5URT4_TSUPD
AccessioniPrimary (citable) accession number: D5URT4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: March 28, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health