D5UQA0 (D5UQA0_TSUPD) Unreviewed, UniProtKB/TrEMBL
Last modified
May 1, 2013.
Version 24.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Submitted name: Isocitrate dehydrogenase, NADP-dependent EMBL ADG78870.1 EC=1.1.1.42 EMBL ADG78870.1 | ||
| Gene names |
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| Organism | Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) (Corynebacterium paurometabolum) [Complete proteome] [HAMAP] EMBL ADG78870.1 | ||
| Taxonomic identifier | 521096 [NCBI] | ||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Tsukamurellaceae › Tsukamurella ›  |
Protein attributes
| Sequence length | 745 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Cofactor | Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3 |
Ontologies
| Keywords | |
|---|---|
| Ligand | Magnesium PIRSR PIRSR009407-3 Metal-binding PIRSR PIRSR009407-3 |
| Molecular function | Oxidoreductase EMBL ADG78870.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro |
| Molecular_function | isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Regions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Region | 134 – 141 | 8 | Substrate binding By similarity PIRSR PIRSR009407-2 | ||||||
Sites | |||||||||
| Metal binding | 352 | 1 | Magnesium or manganese By similarity PIRSR PIRSR009407-3 | ||||||
| Metal binding | 551 | 1 | Magnesium or manganese By similarity PIRSR PIRSR009407-3 | ||||||
| Metal binding | 555 | 1 | Magnesium or manganese By similarity PIRSR PIRSR009407-3 | ||||||
| Binding site | 147 | 1 | Substrate By similarity PIRSR PIRSR009407-2 | ||||||
| Binding site | 550 | 1 | Substrate By similarity PIRSR PIRSR009407-2 | ||||||
| Site | 257 | 1 | Critical for catalysis By similarity PIRSR PIRSR009407-1 | ||||||
| Site | 422 | 1 | Critical for catalysis By similarity PIRSR PIRSR009407-1 | ||||||
Sequences
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References
| [1] | "The complete chromosome of Tsukamurella paurometabola DSM 20162." US DOE Joint Genome Institute (JGI-PGF) Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Munk A.C., Brettin T., Detter J.C., Tapia R., Han C.  Eisen J.A.Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP001966 Genomic DNA. Translation: ADG78870.1. |
| RefSeq | YP_003647209.1. NC_014158.1. |
3D structure databases | |
| ProteinModelPortal | D5UQA0. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | ADG78870; ADG78870; Tpau_2261. |
| GeneID | 9156417. |
| KEGG | tpr:Tpau_2261. |
| PATRIC | 38307825. VBITsuPau718_2263. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HOG000240860. |
| KO | K00031. |
Family and domain databases | |
| Gene3D | 3.40.718.10. 3 hits. |
| InterPro | IPR004436. Isocitrate_DH_NADP_mono. IPR024084. IsoPropMal-DH-like_dom. [Graphical view] |
| Pfam | PF03971. IDH. 1 hit. [Graphical view] |
| PIRSF | PIRSF009407. IDH_monmr. 1 hit. |
| TIGRFAMs | TIGR00178. monomer_idh. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | D5UQA0_TSUPD | ||||||||
| Accession | Primary (citable) accession number: D5UQA0 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||