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Protein

Elongation factor Tu

Gene

tuf

Organism
Cellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi83 – 87GTPUniRule annotation5
Nucleotide bindingi138 – 141GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Cfla_2661Imported
OrganismiCellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)Imported
Taxonomic identifieri446466 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesCellulomonadaceaeCellulomonas
Proteomesi
  • UP000000849 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi446466.Cfla_2661.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206Tr-type GInterPro annotationAdd BLAST197

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
HOGENOMiHOG000229290.
KOiK02358.
OMAiYGHIDCP.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiView protein in InterPro
IPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel_sf.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
PfamiView protein in Pfam
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D5UIY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKAKFERTK PHVNIGTIGH VDHGKTTLTA AISKVLHDKY PELNPFTPFD
60 70 80 90 100
EIDKAPEEKQ RGITINIAHV EYQTEKRHYA HVDAPGHADY IKNMITGAAQ
110 120 130 140 150
MDGAILVVAA TDGPMAQTRE HVLLARQVGV PYLLVALNKS DMVDDEEILE
160 170 180 190 200
LVEMEVRELL SSQDFDGDNA PVVRVSGLKA LEGDPQWVKS VEDLLDAVDE
210 220 230 240 250
NVPDPVREID KPFLMPIEDV FTITGRGTVV TGRVERGSLK VNEEVEIVGI
260 270 280 290 300
KEKAIKTTVT GVEMFRKLLD YAEAGENVGL LLRGTKREEV ERGQVVVKPG
310 320 330 340 350
SITPHTEFEG QVYILSKDEG GRHNPFYGNY RPQFYFRTTD VTGVITLPEG
360 370 380 390
TEMVMPGDNT EISVTLIQPI AMEEGLGFAI REGGRTVGSG RVTKIIK
Length:397
Mass (Da):43,822
Last modified:July 13, 2010 - v1
Checksum:i005B671F958A769C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001964 Genomic DNA. Translation: ADG75548.1.
RefSeqiWP_013117880.1. NC_014151.1.

Genome annotation databases

EnsemblBacteriaiADG75548; ADG75548; Cfla_2661.
KEGGicfl:Cfla_2661.

Similar proteinsi

Entry informationi

Entry nameiD5UIY2_CELFN
AccessioniPrimary (citable) accession number: D5UIY2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: November 22, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported