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D5UIY2

- D5UIY2_CELFN

UniProt

D5UIY2 - D5UIY2_CELFN

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Protein

Elongation factor Tu

Gene

tuf

Organism
Cellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi83 – 875GTPUniRule annotation
Nucleotide bindingi138 – 1414GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotation

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCFLA446466:GHDJ-2703-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Cfla_2661Imported
OrganismiCellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)Imported
Taxonomic identifieri446466 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeCellulomonadaceaeCellulomonas
ProteomesiUP000000849: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229290.
KOiK02358.
OMAiISAPAAC.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5UIY2 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGKAKFERTK PHVNIGTIGH VDHGKTTLTA AISKVLHDKY PELNPFTPFD
60 70 80 90 100
EIDKAPEEKQ RGITINIAHV EYQTEKRHYA HVDAPGHADY IKNMITGAAQ
110 120 130 140 150
MDGAILVVAA TDGPMAQTRE HVLLARQVGV PYLLVALNKS DMVDDEEILE
160 170 180 190 200
LVEMEVRELL SSQDFDGDNA PVVRVSGLKA LEGDPQWVKS VEDLLDAVDE
210 220 230 240 250
NVPDPVREID KPFLMPIEDV FTITGRGTVV TGRVERGSLK VNEEVEIVGI
260 270 280 290 300
KEKAIKTTVT GVEMFRKLLD YAEAGENVGL LLRGTKREEV ERGQVVVKPG
310 320 330 340 350
SITPHTEFEG QVYILSKDEG GRHNPFYGNY RPQFYFRTTD VTGVITLPEG
360 370 380 390
TEMVMPGDNT EISVTLIQPI AMEEGLGFAI REGGRTVGSG RVTKIIK
Length:397
Mass (Da):43,822
Last modified:July 13, 2010 - v1
Checksum:i005B671F958A769C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001964 Genomic DNA. Translation: ADG75548.1.
RefSeqiWP_013117880.1. NC_014151.1.
YP_003637747.1. NC_014151.1.

Genome annotation databases

EnsemblBacteriaiADG75548; ADG75548; Cfla_2661.
GeneIDi9146565.
KEGGicfl:Cfla_2661.
PATRICi38153371. VBICelFla99035_2686.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001964 Genomic DNA. Translation: ADG75548.1 .
RefSeqi WP_013117880.1. NC_014151.1.
YP_003637747.1. NC_014151.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADG75548 ; ADG75548 ; Cfla_2661 .
GeneIDi 9146565.
KEGGi cfl:Cfla_2661.
PATRICi 38153371. VBICelFla99035_2686.

Phylogenomic databases

HOGENOMi HOG000229290.
KOi K02358.
OMAi ISAPAAC.

Enzyme and pathway databases

BioCyci CFLA446466:GHDJ-2703-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134Imported.

Entry informationi

Entry nameiD5UIY2_CELFN
AccessioniPrimary (citable) accession number: D5UIY2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 29, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3