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D5UIS2 (D5UIS2_CELFN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length410 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site491Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2821Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1481Substrate By similarity HAMAP-Rule MF_01201
Binding site3351Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue491N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D5UIS2 [UniParc].

Last modified July 13, 2010. Version 1.
Checksum: ACD23BCB97DA0DDA

FASTA41041,951
        10         20         30         40         50         60 
MPTHDPRGER LAGVNDFPAR AVVDLGAVRG NVRALAAHAP TAQVMAVVKA DAYGHGLVPS 

        70         80         90        100        110        120 
ALAALEGGAT WLGTAQVPEA LHLRRAGVTG ARILTWLYAP GAPLREAVEA DVDLSVASRW 

       130        140        150        160        170        180 
ALDDVVAAAR EAGRTARVHL KVDTGLGRNG LVPAQLPEVL TAALAAEAEG VVRVVGVWSH 

       190        200        210        220        230        240 
LAFADAPDHA VVAQQAGVFA EAVAAVEAAG ARLEVRHLAN SAATLTSPAL HWDLVRPGIA 

       250        260        270        280        290        300 
VYGLSPVPQL GGPERFGLVP AMTFEAQLAT VKPVPAGSGV SYGHEYVVPH DTVLGVVPVG 

       310        320        330        340        350        360 
YADGVPRHAS GSAERWGGPV QVGGRRLGVA GRVCMDQVVL DLGPGATESA GDRVVLWGDG 

       370        380        390        400        410 
RDGGPTAQDW ADVAGTISYE LVTRLGARVP RTYVDSARVA APAPSEGGGA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001964 Genomic DNA. Translation: ADG75488.1.
RefSeqYP_003637687.1. NC_014151.1.

3D structure databases

ProteinModelPortalD5UIS2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADG75488; ADG75488; Cfla_2600.
GeneID9146504.
KEGGcfl:Cfla_2600.
PATRIC38153247. VBICelFla99035_2624.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.
OMAPSECAGV.

Enzyme and pathway databases

BioCycCFLA446466:GHDJ-2642-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5UIS2_CELFN
AccessionPrimary (citable) accession number: D5UIS2
Entry history
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: July 9, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)