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Protein
Submitted name:

2-oxoglutarate dehydrogenase, E1 subunit

Gene

Cfla_1219

Organism
Cellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciCFLA446466:GHDJ-1236-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, E1 subunitImported
Gene namesi
Ordered Locus Names:Cfla_1219Imported
OrganismiCellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)Imported
Taxonomic identifieri446466 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesCellulomonadaceaeCellulomonas
ProteomesiUP000000849 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi446466.Cfla_1219.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000259587.
KOiK00164.
OMAiKRREPFE.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR011603. 2oxoglutarate_DH_E1.
IPR023213. CAT-like_dom.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

D5UBM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQNAQSDST RADFGANEWL VDELYEQYLK DRNAVDPAWW DFFEGYKPET
60 70 80 90 100
TGAATNGETK DAPRATAAPP APAQPTTART PAAPAVPAAP PAPPVEVTPS
110 120 130 140 150
PVATAQPATA PYAEAATRRT DAPEVQAVDD VQKLRGPAAR VVTNMEASLE
160 170 180 190 200
VPTATSVRAV PAKLMVDNRI VINNHLSRGR GGKVSFTHLI GFALVEAVQE
210 220 230 240 250
MPAMNAAYTL VDGKPGVLQP AHVNLGLAID LAKPDGSRQL LVPSIKKAET
260 270 280 290 300
LDFAQFWTAY EDVVRRARNS KLTVDDFAGT TISLTNPGTI GTVHSVPRLM
310 320 330 340 350
QGQGTIVGVG AMDYPAEFAG TSDEQLNRMG VSKVLTVTST YDHRIIQGAQ
360 370 380 390 400
SGDFLRILGR KLLGEDGFYD RVFAALRVPY EPVRWVRDAN HDPDAEAIKP
410 420 430 440 450
ARVAELIHAY RSRGHLMAET DPLAYRQRKH PDLDVQNHGL TLWDLDRTFP
460 470 480 490 500
TGGFTGRTRA TLREVLGLLR DSYCRTVGVE YMHLQDPRQR RWLQERLESG
510 520 530 540 550
YARTPREDQL RILRRLNAAE AFETFLQTKF VGQKRFSLEG GESLIPLLDA
560 570 580 590 600
ILSRAADGGL DEVGIGMAHR GRLNVLANIA GKSYGQIFSE FEGNQDPKSV
610 620 630 640 650
QGSGDVKYHL GTEGVFTAES GATTAVYLAA NPSHLEAVDP VLEGIVRAKQ
660 670 680 690 700
DRIDLGGDGF SVLPILIHGD AAFAGQGVVF ETLNLAQLRG YRTGGTIHVI
710 720 730 740 750
VNNQVGFTTG PSSSRSSQYA TDVAKGLQVP IFHVNGDDPE AVVRVAELAF
760 770 780 790 800
EYREQFDRDV IIDMVCYRRR GHNEGDDPSM TQPLMYNLIE AKRSVRKLYT
810 820 830 840 850
ETLVARGDIT LEEAEQALRD YQSQLERVFT ETREDGWTPP PADVETVAGL
860 870 880 890 900
ERPESQQEDA GVMVGWQTAV PTSILQRIGQ AHVSPPEGFT VHPKLAQMLA
910 920 930 940 950
KREQMSREGG IDWGFGEILA FGSLLIEGTP VRLAGQDSRR GTFVQRHAVL
960 970 980 990 1000
HDRETGAEWT PLLYLSGDQA KFWVYDSSLS EYAALGFEYG YSVERPDALV
1010 1020 1030 1040 1050
LWEAQFGDFV NGAQTVIDEF ISSAEQKWAQ RSSVVLLLPH GYEGQGPDHS
1060 1070 1080 1090 1100
SARIERFLQL AAEDNMTIAQ PSTPASHFHL LRRQAYQRPR RPLVVFTPKS
1110 1120 1130 1140 1150
MLRLKSASSD VQDFTSGTFR TVIGDDLAAA KADQVTRVLL CSGKVYWDLL
1160 1170 1180 1190 1200
AQRVAANDQQ TAIVRFEQLY PLEPDAIAEA LAPFGDAELV WVQDEPRNQG
1210 1220 1230 1240 1250
PWTFVSTHLP QVVGREVRVV SRPESASPAA GSAKKHAVEQ KSLVTEAFAR
Length:1,250
Mass (Da):137,263
Last modified:July 13, 2010 - v1
Checksum:i2874875682026E20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001964 Genomic DNA. Translation: ADG74121.1.
RefSeqiWP_013116455.1. NC_014151.1.

Genome annotation databases

EnsemblBacteriaiADG74121; ADG74121; Cfla_1219.
KEGGicfl:Cfla_1219.
PATRICi38150399. VBICelFla99035_1223.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001964 Genomic DNA. Translation: ADG74121.1.
RefSeqiWP_013116455.1. NC_014151.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi446466.Cfla_1219.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADG74121; ADG74121; Cfla_1219.
KEGGicfl:Cfla_1219.
PATRICi38150399. VBICelFla99035_1223.

Phylogenomic databases

HOGENOMiHOG000259587.
KOiK00164.
OMAiKRREPFE.

Enzyme and pathway databases

BioCyciCFLA446466:GHDJ-1236-MONOMER.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR011603. 2oxoglutarate_DH_E1.
IPR023213. CAT-like_dom.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134Imported.

Entry informationi

Entry nameiD5UBM6_CELFN
AccessioniPrimary (citable) accession number: D5UBM6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: July 22, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.