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D5U0C7

- D5U0C7_THEAM

UniProt

D5U0C7 - D5U0C7_THEAM

Protein

Glyceraldehyde-3-phosphate dehydrogenase

Gene

gap

Organism
Thermosphaera aggregans (strain DSM 11486 / M11TL)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (13 Jul 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei109 – 1091NAD; via amide nitrogenUniRule annotation
    Active sitei139 – 1391NucleophileUniRule annotation
    Binding sitei167 – 1671NADUniRule annotation
    Binding sitei301 – 3011NAD; via carbonyl oxygenUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi11 – 122NADUniRule annotation

    GO - Molecular functioni

    1. glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity Source: UniProtKB-EC
    2. glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Source: UniProtKB-HAMAP
    3. NAD binding Source: InterPro
    4. NADP binding Source: InterPro

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    GlycolysisUniRule annotationSAAS annotation

    Keywords - Ligandi

    NADUniRule annotationSAAS annotation, NADPUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciTAGG633148:GHBI-310-MONOMER.
    UniPathwayiUPA00109; UER00184.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation (EC:1.2.1.59UniRule annotation)
    Short name:
    GAPDHUniRule annotation
    Alternative name(s):
    NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation
    Gene namesi
    Name:gapUniRule annotation
    Ordered Locus Names:Tagg_0301Imported
    OrganismiThermosphaera aggregans (strain DSM 11486 / M11TL)Imported
    Taxonomic identifieri633148 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeThermosphaera
    ProteomesiUP000002376: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni138 – 1403Glyceraldehyde 3-phosphate bindingUniRule annotation
    Regioni193 – 1942Glyceraldehyde 3-phosphate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000223361.
    KOiK00150.
    OMAiVTVPSHH.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    HAMAPiMF_00559. G3P_dehdrog_arch.
    InterProiIPR020831. GlycerAld/Erythrose_P_DH.
    IPR020830. GlycerAld_3-P_DH_AS.
    IPR020829. GlycerAld_3-P_DH_cat.
    IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
    IPR006436. Glyceraldehyde-3-P_DH_2_arc.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF02800. Gp_dh_C. 1 hit.
    PF00044. Gp_dh_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000149. GAP_DH. 1 hit.
    SMARTiSM00846. Gp_dh_N. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01546. GAPDH-II_archae. 1 hit.
    PROSITEiPS00071. GAPDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D5U0C7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVKVGVNGYG TIGKRVADAI LKNPRFQLVG IVKYNPDYSS KIAFKKGINI    50
    YVPQDKWRDF ESTGITPKGT IQEFLEESSI IIDASPNGKG AANLSLYKGA 100
    GKPAIFQGGE KPEVAELSYS TYCNYDEAFG RKYLRVVSCN TTGILRVLCA 150
    LHREFNVKRA RVLVIRRGAD PKEDARGPIN SIKLESFEDV SHHGKDAMLV 200
    LPSVKIISQA VVVPTTLMHV QYLDIDVASP VTRSQVIEAL SKHARILLVN 250
    PKKTGIDSTS KLIEAARDFL RSRNDIYENI VFENTIIVSD NNISLIQAIH 300
    QESIVVPENM DALYAIANIR LPFEKVVEET DRLLGVGGLK DVF 343
    Length:343
    Mass (Da):37,975
    Last modified:July 13, 2010 - v1
    Checksum:i356D92B0171D6F33
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001939 Genomic DNA. Translation: ADG90577.1.
    RefSeqiYP_003649529.1. NC_014160.1.

    Genome annotation databases

    EnsemblBacteriaiADG90577; ADG90577; Tagg_0301.
    GeneIDi9165314.
    KEGGitag:Tagg_0301.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001939 Genomic DNA. Translation: ADG90577.1 .
    RefSeqi YP_003649529.1. NC_014160.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADG90577 ; ADG90577 ; Tagg_0301 .
    GeneIDi 9165314.
    KEGGi tag:Tagg_0301.

    Phylogenomic databases

    HOGENOMi HOG000223361.
    KOi K00150.
    OMAi VTVPSHH.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00184 .
    BioCyci TAGG633148:GHBI-310-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    HAMAPi MF_00559. G3P_dehdrog_arch.
    InterProi IPR020831. GlycerAld/Erythrose_P_DH.
    IPR020830. GlycerAld_3-P_DH_AS.
    IPR020829. GlycerAld_3-P_DH_cat.
    IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
    IPR006436. Glyceraldehyde-3-P_DH_2_arc.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF02800. Gp_dh_C. 1 hit.
    PF00044. Gp_dh_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000149. GAP_DH. 1 hit.
    SMARTi SM00846. Gp_dh_N. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01546. GAPDH-II_archae. 1 hit.
    PROSITEi PS00071. GAPDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 11486 / M11TLImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DSM 11486.

    Entry informationi

    Entry nameiD5U0C7_THEAM
    AccessioniPrimary (citable) accession number: D5U0C7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3