SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D5U0C7

- D5U0C7_THEAM

UniProt

D5U0C7 - D5U0C7_THEAM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glyceraldehyde-3-phosphate dehydrogenase
Gene
gap, Tagg_0301
Organism
Thermosphaera aggregans (strain DSM 11486 / M11TL)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei109 – 1091NAD; via amide nitrogen By similarityUniRule annotation
Active sitei139 – 1391Nucleophile By similarityUniRule annotation
Binding sitei167 – 1671NAD By similarityUniRule annotation
Binding sitei301 – 3011NAD; via carbonyl oxygen By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi11 – 122NAD By similarityUniRule annotation

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. NADP binding Source: InterPro
  3. glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity Source: UniProtKB-EC
  4. glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

NADUniRule annotationSAAS annotations, NADPUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciTAGG633148:GHBI-310-MONOMER.
UniPathwayiUPA00109; UER00184.

Names & Taxonomyi

Protein namesi
Recommended name:
Glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation (EC:1.2.1.59UniRule annotation)
Short name:
GAPDHUniRule annotation
Alternative name(s):
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene namesi
Name:gapUniRule annotation
Ordered Locus Names:Tagg_0301Imported
OrganismiThermosphaera aggregans (strain DSM 11486 / M11TL)Imported
Taxonomic identifieri633148 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeThermosphaera
ProteomesiUP000002376: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni138 – 1403Glyceraldehyde 3-phosphate binding By similarityUniRule annotation
Regioni193 – 1942Glyceraldehyde 3-phosphate binding By similarityUniRule annotation

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000223361.
KOiK00150.
OMAiVTVPSHH.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00559. G3P_dehdrog_arch.
InterProiIPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000149. GAP_DH. 1 hit.
SMARTiSM00846. Gp_dh_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01546. GAPDH-II_archae. 1 hit.
PROSITEiPS00071. GAPDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5U0C7-1 [UniParc]FASTAAdd to Basket

« Hide

MVKVGVNGYG TIGKRVADAI LKNPRFQLVG IVKYNPDYSS KIAFKKGINI    50
YVPQDKWRDF ESTGITPKGT IQEFLEESSI IIDASPNGKG AANLSLYKGA 100
GKPAIFQGGE KPEVAELSYS TYCNYDEAFG RKYLRVVSCN TTGILRVLCA 150
LHREFNVKRA RVLVIRRGAD PKEDARGPIN SIKLESFEDV SHHGKDAMLV 200
LPSVKIISQA VVVPTTLMHV QYLDIDVASP VTRSQVIEAL SKHARILLVN 250
PKKTGIDSTS KLIEAARDFL RSRNDIYENI VFENTIIVSD NNISLIQAIH 300
QESIVVPENM DALYAIANIR LPFEKVVEET DRLLGVGGLK DVF 343
Length:343
Mass (Da):37,975
Last modified:July 13, 2010 - v1
Checksum:i356D92B0171D6F33
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001939 Genomic DNA. Translation: ADG90577.1.
RefSeqiYP_003649529.1. NC_014160.1.

Genome annotation databases

EnsemblBacteriaiADG90577; ADG90577; Tagg_0301.
GeneIDi9165314.
KEGGitag:Tagg_0301.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001939 Genomic DNA. Translation: ADG90577.1 .
RefSeqi YP_003649529.1. NC_014160.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADG90577 ; ADG90577 ; Tagg_0301 .
GeneIDi 9165314.
KEGGi tag:Tagg_0301.

Phylogenomic databases

HOGENOMi HOG000223361.
KOi K00150.
OMAi VTVPSHH.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00184 .
BioCyci TAGG633148:GHBI-310-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_00559. G3P_dehdrog_arch.
InterProi IPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000149. GAP_DH. 1 hit.
SMARTi SM00846. Gp_dh_N. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01546. GAPDH-II_archae. 1 hit.
PROSITEi PS00071. GAPDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 11486 / M11TL.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 11486.

Entry informationi

Entry nameiD5U0C7_THEAM
AccessioniPrimary (citable) accession number: D5U0C7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: June 11, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi