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D5TG50

- D5TG50_BIFAV

UniProt

D5TG50 - D5TG50_BIFAV

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Protein

Xylose isomerase

Gene

xylA

Organism
Bifidobacterium animalis subsp. lactis (strain V9)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei103 – 1031UniRule annotation
Active sitei106 – 1061UniRule annotation
Metal bindingi234 – 2341Magnesium 1UniRule annotation
Metal bindingi270 – 2701Magnesium 1UniRule annotation
Metal bindingi270 – 2701Magnesium 2UniRule annotation
Metal bindingi273 – 2731Magnesium 2UniRule annotation
Metal bindingi298 – 2981Magnesium 1UniRule annotation
Metal bindingi309 – 3091Magnesium 2UniRule annotation
Metal bindingi311 – 3111Magnesium 2UniRule annotation
Metal bindingi342 – 3421Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciBANI573236:GL92-511-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:BalV_0488Imported
OrganismiBifidobacterium animalis subsp. lactis (strain V9)Imported
Taxonomic identifieri573236 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000007461: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliD5TG50.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000252293.
KOiK01805.
OMAiLFHAHIG.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5TG50-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAGLWDIDKI EYVGRTKGLQ EGLGFQYYDA DKVVAGKKMK DWLRFGVAWW
60 70 80 90 100
HTFDAPLTDP FGDGTAQRPW DGKYSDPMDN ALAKVDYAFE FFTKLGAEYF
110 120 130 140 150
CFHDRDIAPE GDTLRETNAN LDRVVDKIEE NMQSTGVKLL WNTSSLFTNP
160 170 180 190 200
RFVAGASTSP FADVYAYAAA QLKHSLEIGK RLGAENYVFW GGREGYENLW
210 220 230 240 250
VTDMKREQEH MAKFFHMCAD YAKQIGMDAQ FLIEPKAKEP TTHQYDFDAA
260 270 280 290 300
TACNFLRAYD LIDVFKLNLE GNHANLAGHT YQHEIRVARD NGVLGSLDAN
310 320 330 340 350
QGDMLLGWDL DEFPTNLYET TSVMWEVLDE GQIGPHGGLN FDAKPRRTSF
360 370 380 390 400
SAEDLFRAHI AGMDSFAAGL LVADKMHQDK YIEDLVANRY GSYDSGIGKS
410 420 430 440 450
IDDGTATLES LNDYAIDMPQ SEIIASTHPD HLEDVKATIN NYIIDALANA
Length:450
Mass (Da):50,562
Last modified:July 13, 2010 - v1
Checksum:i12AA2B7016389BA8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001892 Genomic DNA. Translation: ADG33076.1.
RefSeqiYP_005580855.1. NC_017217.1.

Genome annotation databases

EnsemblBacteriaiADG33076; ADG33076; BalV_0488.
GeneIDi12170948.
KEGGiblv:BalV_0488.
PATRICi42763330. VBIBifAni108068_0512.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001892 Genomic DNA. Translation: ADG33076.1 .
RefSeqi YP_005580855.1. NC_017217.1.

3D structure databases

ProteinModelPortali D5TG50.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADG33076 ; ADG33076 ; BalV_0488 .
GeneIDi 12170948.
KEGGi blv:BalV_0488.
PATRICi 42763330. VBIBifAni108068_0512.

Phylogenomic databases

HOGENOMi HOG000252293.
KOi K01805.
OMAi LFHAHIG.

Enzyme and pathway databases

BioCyci BANI573236:GL92-511-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of probiotic Bifidobacterium animalis subsp. lactis strain V9."
    Sun Z., Chen X., Wang J., Gao P., Zhou Z., Ren Y., Sun T., Wang L., Meng H., Chen W., Zhang H.
    J. Bacteriol. 192:4080-4081(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: V9Imported.

Entry informationi

Entry nameiD5TG50_BIFAV
AccessioniPrimary (citable) accession number: D5TG50
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 29, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3