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Protein

Superoxide dismutase [Cu-Zn]

Gene

sodC

Organism
Legionella pneumophila serogroup 1 (strain 2300/99 Alcoy)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciLPNE423212:GHRR-2486-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sodCImported
Ordered Locus Names:lpa_03363Imported
OrganismiLegionella pneumophila serogroup 1 (strain 2300/99 Alcoy)Imported
Taxonomic identifieri423212 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
ProteomesiUP000000926 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD5T7M5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000263449.
KOiK04565.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5T7M5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKSGIILIG TILFSSMAIA DDLTAPIYTT GPKPVAIGKV TFTQTPYGVL
60 70 80 90 100
ITPDLTNLPE GPHGFHLHKN ADCGNHGMHA EGHYDPQNTN SHQGPYGNGH
110 120 130 140 150
LGDLPVLYVT SNGKAMIPTL APRLKLNDMH NLAVMIHANG DTYSDNPPQG
160
GGGDRIACGV IK
Length:162
Mass (Da):17,116
Last modified:July 13, 2010 - v1
Checksum:i47CBEC2B92F0B8B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001828 Genomic DNA. Translation: ADG25689.1.
RefSeqiWP_011947192.1. NC_014125.1.
YP_003619641.1. NC_014125.1.

Genome annotation databases

EnsemblBacteriaiADG25689; ADG25689; lpa_03363.
KEGGilpa:lpa_03363.
PATRICi38182963. VBILegPne70474_2573.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001828 Genomic DNA. Translation: ADG25689.1.
RefSeqiWP_011947192.1. NC_014125.1.
YP_003619641.1. NC_014125.1.

3D structure databases

ProteinModelPortaliD5T7M5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADG25689; ADG25689; lpa_03363.
KEGGilpa:lpa_03363.
PATRICi38182963. VBILegPne70474_2573.

Phylogenomic databases

HOGENOMiHOG000263449.
KOiK04565.

Enzyme and pathway databases

BioCyciLPNE423212:GHRR-2486-MONOMER.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Legionella pneumophila pangenome reveals strain-specific virulence factors."
    D'Auria G., Jimenez-Hernandez N., Peris-Bondia F., Moya A., Latorre A.
    BMC Genomics 11:181-181(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2300/99 AlcoyImported.

Entry informationi

Entry nameiD5T7M5_LEGP2
AccessioniPrimary (citable) accession number: D5T7M5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: May 27, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.