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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Leuconostoc kimchii (strain IMSNU 11154 / KCTC 2386 / IH25)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation

Enzyme and pathway databases

BioCyciLKIM762051:GJOL-1607-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:LKI_07680Imported
OrganismiLeuconostoc kimchii (strain IMSNU 11154 / KCTC 2386 / IH25)Imported
Taxonomic identifieri762051 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
ProteomesiUP000002362 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000038601.
KOiK01595.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

D5T4D7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQRKIPTIM GTQHPDNANA PFWDASQQPF ISAYREMNEA FENFSELNVD
60 70 80 90 100
EYMWDWEGKH ADAAVIDRLF STEYDYFKKD QIGRDKFLTF RFPNIWEEKG
110 120 130 140 150
YNLMQAMTAI LSSEDFAHDL GFDQRPLFET ILPMAQRADQ LIEMQVLFEK
160 170 180 190 200
LANFKSVEFT KNDRNTPYIE MIPLFEDFNT QLHAPEILKE YLKLHEEHFG
210 220 230 240 250
FRPKYLRVFL AGSDSALTAG FMSSITGNKL AIARLHEFAQ EENIDIYPIS
260 270 280 290 300
GTGSAIFRGG LSPRRIDRYL TEFPGVRTAT VQSAFRYDFP LEEVQQAIAE
310 320 330 340 350
LKEKLPVATP LKISRDDQKI LAEVAEESAE FYAHTLDQLV PDMQPIFKAF
360 370 380 390 400
PKRRDRRQHV GVLGYSRSVD GIELPRAINF TGSFYSIGVP PEFIGFGRAL
410 420 430 440 450
AHLNADHLSV FVRNYPSMKQ DFRELAAYVN LDALQILKTQ SPAWADVEED
460 470 480 490 500
IMTLKNIFDL EIGPKTREQQ QHAAIALQVV QIKEGAPIAT TALINRMAQL

RHFLG
Length:505
Mass (Da):57,929
Last modified:July 13, 2010 - v1
Checksum:i79DC1C9801FF72F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001758 Genomic DNA. Translation: ADG41075.1.
RefSeqiYP_003622044.1. NC_014136.1.

Genome annotation databases

EnsemblBacteriaiADG41075; ADG41075; LKI_07680.
KEGGilki:LKI_07680.
PATRICi38187689. VBILeuKim161478_1500.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001758 Genomic DNA. Translation: ADG41075.1.
RefSeqiYP_003622044.1. NC_014136.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADG41075; ADG41075; LKI_07680.
KEGGilki:LKI_07680.
PATRICi38187689. VBILeuKim161478_1500.

Phylogenomic databases

HOGENOMiHOG000038601.
KOiK01595.

Enzyme and pathway databases

BioCyciLKIM762051:GJOL-1607-MONOMER.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence analysis of Leuconostoc kimchii IMSNU 11154."
    Oh H.M., Cho Y.J., Kim B.K., Roe J.H., Kang S.O., Nahm B.H., Jeong G., Han H.U., Chun J.
    J. Bacteriol. 192:3844-3845(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IMSNU 11154 / KCTC 2386 / IH25Imported.

Entry informationi

Entry nameiD5T4D7_LEUKI
AccessioniPrimary (citable) accession number: D5T4D7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: April 1, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.