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D5T439

- D5T439_LEUKI

UniProt

D5T439 - D5T439_LEUKI

Protein

Thymidine kinase

Gene

tdk

Organism
Leuconostoc kimchii (strain IMSNU 11154 / KCTC 2386 / IH25)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (13 Jul 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei87 – 871Proton acceptorUniRule annotation
    Metal bindingi144 – 1441ZincUniRule annotation
    Metal bindingi147 – 1471ZincUniRule annotation
    Metal bindingi181 – 1811ZincUniRule annotation
    Metal bindingi184 – 1841ZincUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi9 – 168ATPUniRule annotation
    Nucleotide bindingi86 – 894ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP
    3. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, ZincUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciLKIM762051:GJOL-1504-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotation
    Ordered Locus Names:LKI_07190Imported
    OrganismiLeuconostoc kimchii (strain IMSNU 11154 / KCTC 2386 / IH25)Imported
    Taxonomic identifieri762051 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
    ProteomesiUP000002362: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD5T439.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000076391.
    KOiK00857.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D5T439-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAQLFFEYGA MSSGKSIEIL KVAHNYESQG RQVLLMTPMI DTRAGVGVVS    50
    SRIGLSREAL AVKPEDDLFE LIAGMKSDNL AVVLVDEAQF LSPSQVDELA 100
    YVVDHLHIPV MAFGLKQDAF NHLFEGSQRL IELADKLEEM KTICSFCGKK 150
    ATTQLRIVDG KPQRAGEQVF IGGDEAYIPT CRRHWYHPDA EKIAAMFPIK 200
    K 201
    Length:201
    Mass (Da):22,373
    Last modified:July 13, 2010 - v1
    Checksum:iE5EC39AFC8C7CF65
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001758 Genomic DNA. Translation: ADG40977.1.
    RefSeqiYP_003621946.1. NC_014136.1.

    Genome annotation databases

    EnsemblBacteriaiADG40977; ADG40977; LKI_07190.
    GeneIDi9134016.
    KEGGilki:LKI_07190.
    PATRICi38187495. VBILeuKim161478_1408.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001758 Genomic DNA. Translation: ADG40977.1 .
    RefSeqi YP_003621946.1. NC_014136.1.

    3D structure databases

    ProteinModelPortali D5T439.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADG40977 ; ADG40977 ; LKI_07190 .
    GeneIDi 9134016.
    KEGGi lki:LKI_07190.
    PATRICi 38187495. VBILeuKim161478_1408.

    Phylogenomic databases

    HOGENOMi HOG000076391.
    KOi K00857.

    Enzyme and pathway databases

    BioCyci LKIM762051:GJOL-1504-MONOMER.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence analysis of Leuconostoc kimchii IMSNU 11154."
      Oh H.M., Cho Y.J., Kim B.K., Roe J.H., Kang S.O., Nahm B.H., Jeong G., Han H.U., Chun J.
      J. Bacteriol. 192:3844-3845(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IMSNU 11154 / KCTC 2386 / IH25Imported.

    Entry informationi

    Entry nameiD5T439_LEUKI
    AccessioniPrimary (citable) accession number: D5T439
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3