Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alanine racemase

Gene

LKI_04810

Organism
Leuconostoc kimchii (strain IMSNU 11154 / KCTC 2386 / IH25)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (LKI_04810), Alanine racemase (LKI_04215)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei42Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei141SubstrateUniRule annotation1
Active sitei270Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei317Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotation
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciLKIM762051:GJOL-983-MONOMER
UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:LKI_04810Imported
OrganismiLeuconostoc kimchii (strain IMSNU 11154 / KCTC 2386 / IH25)Imported
Taxonomic identifieri762051 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
Proteomesi
  • UP000002362 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei42N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi762051.LKI_04810

Structurei

3D structure databases

ProteinModelPortaliD5T2K4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini249 – 374Ala_racemase_CInterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CJ4 Bacteria
COG0787 LUCA
HOGENOMiHOG000031444
KOiK01775
OrthoDBiPOG091H022F

Family and domain databases

Gene3Di2.40.37.10, 2 hits
3.20.20.10, 1 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

D5T2K4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIENDNVVTR PTWIEIDLKA IQYNARLIMK HADATRMIAV VKADAYGHGA
60 70 80 90 100
VAVTKALYDI GIRDFAVATI SEALILRQEV DHDDFNILLL GVQDVSQVKL
110 120 130 140 150
MVENRLMPAV GTLEWLYQAV SFLTDSQILD VHLAVDTGMG RMGANSQADV
160 170 180 190 200
TELYHFIQKS SQLRLNGVFT HFATADDDNE AYYKQQVTKL YQWVNGAGIP
210 220 230 240 250
KKYWHLANSG SALWHHNEID TDTIRVGSVL YGFNPGSPAL DMSIKLKNVL
260 270 280 290 300
SLKSRMGAVH QLQAGESVSY GATYTAEHAQ WVATLPIGYA DGYLRRMGGM
310 320 330 340 350
KVLVSGEEAQ VVGRITMDQI VIALDKQYPV GTEVTLIGRD GDEKITIEDF
360 370
ATYAGTIPHE ILTSFGVRLP RIYH
Length:374
Mass (Da):41,472
Last modified:July 13, 2010 - v1
Checksum:i934200A6451596DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001758 Genomic DNA Translation: ADG40503.1
RefSeqiWP_013103099.1, NC_014136.1

Genome annotation databases

EnsemblBacteriaiADG40503; ADG40503; LKI_04810
KEGGilki:LKI_04810
PATRICifig|762051.18.peg.969

Similar proteinsi

Entry informationi

Entry nameiD5T2K4_LEUKI
AccessioniPrimary (citable) accession number: D5T2K4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: June 20, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health