ID   D5SUX4_PLAL2            Unreviewed;       559 AA.
AC   D5SUX4;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   OrderedLocusNames=Plim_3447 {ECO:0000313|EMBL:ADG69260.1};
OS   Planctopirus limnophila (strain ATCC 43296 / DSM 3776 / IFAM 1008 / Mu 290)
OS   (Planctomyces limnophilus).
OC   Bacteria; Planctomycetota; Planctomycetia; Planctomycetales;
OC   Planctomycetaceae; Planctopirus.
OX   NCBI_TaxID=521674 {ECO:0000313|EMBL:ADG69260.1, ECO:0000313|Proteomes:UP000002220};
RN   [1] {ECO:0000313|EMBL:ADG69260.1, ECO:0000313|Proteomes:UP000002220}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43296 / DSM 3776 / IFAM 1008 / 290
RC   {ECO:0000313|Proteomes:UP000002220};
RX   PubMed=21304691; DOI=10.4056/sigs.1052813;
RA   Labutti K., Sikorski J., Schneider S., Nolan M., Lucas S.,
RA   Glavina Del Rio T., Tice H., Cheng J.F., Goodwin L., Pitluck S.,
RA   Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Tindall B.J., Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Lapidus A.;
RT   "Complete genome sequence of Planctomyces limnophilus type strain (Mu
RT   290).";
RL   Stand. Genomic Sci. 3:47-56(2010).
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DR   EMBL; CP001744; ADG69260.1; -; Genomic_DNA.
DR   AlphaFoldDB; D5SUX4; -.
DR   STRING; 521674.Plim_3447; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   KEGG; plm:Plim_3447; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_487335_0_0_0; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000002220; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ADG69260.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002220};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..559
FT                   /note="exo-alpha-sialidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003076327"
FT   DOMAIN          236..533
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   559 AA;  60569 MW;  4D41AE9E3F963A9E CRC64;
     MQCLLTRICL AVTLGCMTSM NMLGLMASEP EVTTSVVVYS GKAAELKWIG KPWASIEDPK
     GSTSALLASG QNRWLLSRSG IGAGDFQIRV RLQLAKLDGT AAAFDFGSSR FGLDGKAGLL
     FVEGPLFRNQ PAATLKIADL VQPGAPFLLE VIRKDEQTRF LINGQSVYTL DGWKGSVGRV
     GLRPWRNEMA VFDFSIKGNL YELPAPPEPL FPSGFAGGTE GYHTFRIPSL TTTRSGTLLA
     LCEGRKNSTG DSGDIDLVMK RSTDGGKTWS QPVVLWDNGE NTCGNPCLVV DQTTGELLLL
     ATWNLGDDHE SEIIAQTSRD TRRVYVLRSK DDGLTWSQPV EITKDVKQPD WTWYATGPGG
     GIQIQQGSHA GRLVIPCDHI EARTKKYYSH VIYSDDHGQT WKLGGSTPAA GVNECEVVEL
     TGGKLLLNMR NASASRQRQT SMSEDGGLTW SELKSDAALI EPVCQAAILR ASWPARSEPG
     WILFSNPAST TSRTNLTVRG SRDDGQTWPV SKVLYTGPAA YSDLALLPDG KVGCLFEAGE
     ANYAESIVFV TFGLDELTT
//