D5K9T7 (D5K9T7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
POU domain transcription factor OCT4-pg4 EMBL ADE48574.1

Gene names

Name:

POU5F1P4 EMBL ADE48574.1

Organism

Homo sapiens (Human) EMBL ADE48574.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU000682.
Sequence similarities	Contains 1 POU-specific domain. SAAS SAAS000327 Contains 1 homeobox DNA-binding domain. SAAS SAAS013847

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000682 SAAS SAAS013847
Domain	Homeobox RuleBase RU000682 SAAS SAAS013847
Ligand	DNA-binding RuleBase RU000682 SAAS SAAS013847
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D5K9T7 [UniParc]. Last modified June 15, 2010. Version 1. Checksum: 736304AAE534645E	FASTA	286	31,189
	10 20 30 40 50 60 MPAFLPPPGG GGDGPGGPEP GWVDPRTWLS FQGPPGGPGI GPGVGSGSEV WGIPPCPPLY 70 80 90 100 110 120 EFCGGMAYCG PQVGVRLVPQ GGLETSQPEG EAGVRVESNS DGTSLEPCTV PPGAVKLEKE 130 140 150 160 170 180 KLEQNPQESQ NIKALQKELE QFAKLLKQKR ITLGYTQADV GLTLGVLFGK VFSQTTICRF 190 200 210 220 230 240 EGLQLSFKNM CKLRPLLQKW EEEADNNENL QETCKAETLL QARKRKRTSI ENRVRGNLEN 250 260 270 280 LFLQCPKPTL QQISHIAQQL GLEKDVVRVW FCNRCQKGKQ SSSDYA

References

[1]	"Expression of OCT4 Pseudogenes in Human Somatic Tumors." Zhao S., Yuan Q., Liu S., Zhang Y., Liu H., Wang F., Liu K., Hao A. Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Expression of OCT4 pseudogenes in two human somatic tumours: glioma and breast carcinoma." Zhao S., Yuan Q., Guo Y., Liu S., Zhang Y., Wang J., Liu H., Wang F., Liu K., Ling E.-A., Hao A. Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Glioma WHO grade II EMBL ADW77375.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GU480852 mRNA. Translation: ADE48574.1. HQ122737 mRNA. Translation: ADW77375.1. HQ122738 mRNA. Translation: ADW77376.1. HQ122739 mRNA. Translation: ADW77377.1.
IPI	IPI00032965.
UniGene	Hs.632482.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.10.60. 1 hit. 1.10.260.40. 1 hit.
InterPro	IPR017970. Homeobox_CS. IPR001356. Homeodomain. IPR009057. Homeodomain-like. IPR010982. Lambda_DNA-bd_dom. IPR013847. POU. IPR015585. POU_dom_5. IPR000327. POU_specific. [Graphical view]
PANTHER	PTHR11636:SF15. PTHR11636:SF15. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. PF00157. Pou. 1 hit. [Graphical view]
PRINTS	PR00028. POUDOMAIN.
SMART	SM00389. HOX. 1 hit. SM00352. POU. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit. SSF47413. Lambda_like_DNA. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS00035. POU_1. 1 hit. PS00465. POU_2. 1 hit. PS51179. POU_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35491872.

Entry information

Entry name

D5K9T7_HUMAN

Accession

Primary (citable) accession number: D5K9T7

Entry history

Integrated into UniProtKB/TrEMBL:	June 15, 2010
Last sequence update:	June 15, 2010
Last modified:	April 3, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.