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D5K9S8

- D5K9S8_HUMAN

UniProt

D5K9S8 - D5K9S8_HUMAN

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Protein

POU domain protein

Gene

POU5F1P4

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

TranscriptionUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:POU5F1P4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiD5K9S8.

Structurei

3D structure databases

ProteinModelPortaliD5K9S8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotation
Contains 1 POU-specific domain.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation
Contains POU-specific domain.SAAS annotation
Contains homeobox DNA-binding domain.SAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR015585. POU_dom_5.
IPR000327. POU_specific.
[Graphical view]
PANTHERiPTHR11636:SF15. PTHR11636:SF15. 1 hit.
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5K9S8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPAFLPPPGG GGDGPGGPEP GWVDPRTWLS FQGPPGGPGI GPGVGSGSEV
60 70 80 90 100
WGIPPCPPLY EFCGGMAYCG PQVGVRLVPQ GGLETSQPEG EAGVRVESNS
110 120 130 140 150
DGTSLEPCTV PPGAVKLEKE KLEQNPQESQ NIKALQKELE QFAKLLKQKR
160 170 180 190 200
ITLGYTQADV GLTLGVLFGK VFSQTTICRF EGLQLSFKNM CKLRPLLQKW
210 220 230 240 250
VEEADNNENL QETCKAETLL QARKRKRTSI ENRVRGNLEN LFLQCPKPTL
260 270 280
QQISHIAQQL GLEKDVVRVW FCNRCQKGKQ SSSDYA
Length:286
Mass (Da):31,159
Last modified:June 15, 2010 - v1
Checksum:iA2401689E52BA114
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU480839 mRNA. Translation: ADE48565.1.
GU480848 mRNA. Translation: ADE48573.1.
GU480862 mRNA. Translation: ADE48578.1.
GU480867 mRNA. Translation: ADE48582.1.
GU480875 mRNA. Translation: ADE48589.1.
GU480879 mRNA. Translation: ADE48592.1.
GU480881 mRNA. Translation: ADE48594.1.
GU480882 mRNA. Translation: ADE48595.1.
GU480904 mRNA. Translation: ADE48608.1.
HQ122676 mRNA. Translation: ADW77328.1.
HQ122677 mRNA. Translation: ADW77329.1.
HQ122681 mRNA. Translation: ADW77330.1.
HQ122687 mRNA. Translation: ADW77334.1.
HQ122690 mRNA. Translation: ADW77335.1.
HQ122698 mRNA. Translation: ADW77340.1.
HQ122700 mRNA. Translation: ADW77342.1.
HQ122701 mRNA. Translation: ADW77343.1.
HQ122703 mRNA. Translation: ADW77345.1.
HQ122704 mRNA. Translation: ADW77346.1.
HQ122705 mRNA. Translation: ADW77347.1.
HQ122708 mRNA. Translation: ADW77349.1.
HQ122709 mRNA. Translation: ADW77350.1.
HQ122732 mRNA. Translation: ADW77370.1.
HQ122733 mRNA. Translation: ADW77371.1.
HQ122734 mRNA. Translation: ADW77372.1.
HQ122735 mRNA. Translation: ADW77373.1.
HQ122736 mRNA. Translation: ADW77374.1.
HQ122740 mRNA. Translation: ADW77378.1.
HQ122741 mRNA. Translation: ADW77379.1.
HQ122742 mRNA. Translation: ADW77380.1.
HQ122743 mRNA. Translation: ADW77381.1.
HQ122744 mRNA. Translation: ADW77382.1.
HQ122746 mRNA. Translation: ADW77383.1.
HQ122748 mRNA. Translation: ADW77384.1.
HQ122757 mRNA. Translation: ADW77393.1.
HQ122758 mRNA. Translation: ADW77394.1.
HQ122760 mRNA. Translation: ADW77396.1.
HQ122761 mRNA. Translation: ADW77397.1.
HQ122763 mRNA. Translation: ADW77399.1.
HQ122764 mRNA. Translation: ADW77400.1.
HQ122765 mRNA. Translation: ADW77401.1.
HQ122766 mRNA. Translation: ADW77402.1.
HQ122767 mRNA. Translation: ADW77403.1.
HQ122768 mRNA. Translation: ADW77404.1.
HQ122771 mRNA. Translation: ADW77406.1.
HQ122772 mRNA. Translation: ADW77407.1.
HQ122774 mRNA. Translation: ADW77409.1.
HQ122775 mRNA. Translation: ADW77410.1.
HQ122778 mRNA. Translation: ADW77412.1.
HQ122779 mRNA. Translation: ADW77413.1.
HQ122780 mRNA. Translation: ADW77414.1.
HQ122801 mRNA. Translation: ADW77433.1.
HQ122805 mRNA. Translation: ADW77435.1.
HQ122808 mRNA. Translation: ADW77438.1.
HQ122813 mRNA. Translation: ADW77442.1.
HQ122839 mRNA. Translation: ADW77465.1.
UniGeneiHs.632482.

Genome annotation databases

UCSCiuc010pgd.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU480839 mRNA. Translation: ADE48565.1 .
GU480848 mRNA. Translation: ADE48573.1 .
GU480862 mRNA. Translation: ADE48578.1 .
GU480867 mRNA. Translation: ADE48582.1 .
GU480875 mRNA. Translation: ADE48589.1 .
GU480879 mRNA. Translation: ADE48592.1 .
GU480881 mRNA. Translation: ADE48594.1 .
GU480882 mRNA. Translation: ADE48595.1 .
GU480904 mRNA. Translation: ADE48608.1 .
HQ122676 mRNA. Translation: ADW77328.1 .
HQ122677 mRNA. Translation: ADW77329.1 .
HQ122681 mRNA. Translation: ADW77330.1 .
HQ122687 mRNA. Translation: ADW77334.1 .
HQ122690 mRNA. Translation: ADW77335.1 .
HQ122698 mRNA. Translation: ADW77340.1 .
HQ122700 mRNA. Translation: ADW77342.1 .
HQ122701 mRNA. Translation: ADW77343.1 .
HQ122703 mRNA. Translation: ADW77345.1 .
HQ122704 mRNA. Translation: ADW77346.1 .
HQ122705 mRNA. Translation: ADW77347.1 .
HQ122708 mRNA. Translation: ADW77349.1 .
HQ122709 mRNA. Translation: ADW77350.1 .
HQ122732 mRNA. Translation: ADW77370.1 .
HQ122733 mRNA. Translation: ADW77371.1 .
HQ122734 mRNA. Translation: ADW77372.1 .
HQ122735 mRNA. Translation: ADW77373.1 .
HQ122736 mRNA. Translation: ADW77374.1 .
HQ122740 mRNA. Translation: ADW77378.1 .
HQ122741 mRNA. Translation: ADW77379.1 .
HQ122742 mRNA. Translation: ADW77380.1 .
HQ122743 mRNA. Translation: ADW77381.1 .
HQ122744 mRNA. Translation: ADW77382.1 .
HQ122746 mRNA. Translation: ADW77383.1 .
HQ122748 mRNA. Translation: ADW77384.1 .
HQ122757 mRNA. Translation: ADW77393.1 .
HQ122758 mRNA. Translation: ADW77394.1 .
HQ122760 mRNA. Translation: ADW77396.1 .
HQ122761 mRNA. Translation: ADW77397.1 .
HQ122763 mRNA. Translation: ADW77399.1 .
HQ122764 mRNA. Translation: ADW77400.1 .
HQ122765 mRNA. Translation: ADW77401.1 .
HQ122766 mRNA. Translation: ADW77402.1 .
HQ122767 mRNA. Translation: ADW77403.1 .
HQ122768 mRNA. Translation: ADW77404.1 .
HQ122771 mRNA. Translation: ADW77406.1 .
HQ122772 mRNA. Translation: ADW77407.1 .
HQ122774 mRNA. Translation: ADW77409.1 .
HQ122775 mRNA. Translation: ADW77410.1 .
HQ122778 mRNA. Translation: ADW77412.1 .
HQ122779 mRNA. Translation: ADW77413.1 .
HQ122780 mRNA. Translation: ADW77414.1 .
HQ122801 mRNA. Translation: ADW77433.1 .
HQ122805 mRNA. Translation: ADW77435.1 .
HQ122808 mRNA. Translation: ADW77438.1 .
HQ122813 mRNA. Translation: ADW77442.1 .
HQ122839 mRNA. Translation: ADW77465.1 .
UniGenei Hs.632482.

3D structure databases

ProteinModelPortali D5K9S8.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi D5K9S8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc010pgd.2. human.

Miscellaneous databases

NextBioi 35491865.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR015585. POU_dom_5.
IPR000327. POU_specific.
[Graphical view ]
PANTHERi PTHR11636:SF15. PTHR11636:SF15. 1 hit.
Pfami PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view ]
PRINTSi PR00028. POUDOMAIN.
SMARTi SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Expression of OCT4 Pseudogenes in Human Somatic Tumors."
    Zhao S., Yuan Q., Liu S., Zhang Y., Liu H., Wang F., Liu K., Hao A.
    Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Breast carcinomaImported and GliomaImported.
  2. "Expression of OCT4 pseudogenes in two human somatic tumours: glioma and breast carcinoma."
    Zhao S., Yuan Q., Guo Y., Liu S., Zhang Y., Wang J., Liu H., Wang F., Liu K., Ling E.-A., Hao A.
    Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Breast cancer luminal A subtypeImported, Glioma WHO grade IIImported, Glioma WHO grade IIIImported and Glioma WHO grade IVImported.

Entry informationi

Entry nameiD5K9S8_HUMAN
AccessioniPrimary (citable) accession number: D5K9S8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: November 26, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.