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Protein

POU domain protein

Gene

POU5F1P4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi223 – 282HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:POU5F1P4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini131 – 205POU-specificInterPro annotationAdd BLAST75
Domaini221 – 281Homeobox DNA-bindingInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR015585. POU_dom_5.
PANTHERiPTHR11636:SF100. PTHR11636:SF100. 1 hit.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.

Sequencei

Sequence statusi: Complete.

D5K9S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAFLPPPGG GGDGPGGPEP GWVDPRTWLS FQGPPGGPGI GPGVGSGSEV
60 70 80 90 100
WGIPPCPPLY EFCGGMAYCG PQVGVRLVPQ GGLETSQPEG EAGVRVESNS
110 120 130 140 150
DGTSLEPCTV PPGAVKLEKE KLEQNPQESQ NIKALQKELE QFAKLLKQKR
160 170 180 190 200
ITLGYTQADV GLTLGVLFGK VFSQTTICRF EGLQLSFKNM CKLRPLLQKW
210 220 230 240 250
VEEADNNENL QETCKAETLL QARKRKRTSI ENRVRGNLEN LFLQCPKPTL
260 270 280
QQISHIAQQL GLEKDVVRVW FCNRCQKGKQ SSSDYA
Length:286
Mass (Da):31,159
Last modified:June 15, 2010 - v1
Checksum:iA2401689E52BA114
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU480839 mRNA. Translation: ADE48565.1.
GU480848 mRNA. Translation: ADE48573.1.
GU480862 mRNA. Translation: ADE48578.1.
GU480867 mRNA. Translation: ADE48582.1.
GU480875 mRNA. Translation: ADE48589.1.
GU480879 mRNA. Translation: ADE48592.1.
GU480881 mRNA. Translation: ADE48594.1.
GU480882 mRNA. Translation: ADE48595.1.
GU480904 mRNA. Translation: ADE48608.1.
HQ122676 mRNA. Translation: ADW77328.1.
HQ122677 mRNA. Translation: ADW77329.1.
HQ122681 mRNA. Translation: ADW77330.1.
HQ122687 mRNA. Translation: ADW77334.1.
HQ122690 mRNA. Translation: ADW77335.1.
HQ122698 mRNA. Translation: ADW77340.1.
HQ122700 mRNA. Translation: ADW77342.1.
HQ122701 mRNA. Translation: ADW77343.1.
HQ122703 mRNA. Translation: ADW77345.1.
HQ122704 mRNA. Translation: ADW77346.1.
HQ122705 mRNA. Translation: ADW77347.1.
HQ122708 mRNA. Translation: ADW77349.1.
HQ122709 mRNA. Translation: ADW77350.1.
HQ122732 mRNA. Translation: ADW77370.1.
HQ122733 mRNA. Translation: ADW77371.1.
HQ122734 mRNA. Translation: ADW77372.1.
HQ122735 mRNA. Translation: ADW77373.1.
HQ122736 mRNA. Translation: ADW77374.1.
HQ122740 mRNA. Translation: ADW77378.1.
HQ122741 mRNA. Translation: ADW77379.1.
HQ122742 mRNA. Translation: ADW77380.1.
HQ122743 mRNA. Translation: ADW77381.1.
HQ122744 mRNA. Translation: ADW77382.1.
HQ122746 mRNA. Translation: ADW77383.1.
HQ122748 mRNA. Translation: ADW77384.1.
HQ122757 mRNA. Translation: ADW77393.1.
HQ122758 mRNA. Translation: ADW77394.1.
HQ122760 mRNA. Translation: ADW77396.1.
HQ122761 mRNA. Translation: ADW77397.1.
HQ122763 mRNA. Translation: ADW77399.1.
HQ122764 mRNA. Translation: ADW77400.1.
HQ122765 mRNA. Translation: ADW77401.1.
HQ122766 mRNA. Translation: ADW77402.1.
HQ122767 mRNA. Translation: ADW77403.1.
HQ122768 mRNA. Translation: ADW77404.1.
HQ122771 mRNA. Translation: ADW77406.1.
HQ122772 mRNA. Translation: ADW77407.1.
HQ122774 mRNA. Translation: ADW77409.1.
HQ122775 mRNA. Translation: ADW77410.1.
HQ122778 mRNA. Translation: ADW77412.1.
HQ122779 mRNA. Translation: ADW77413.1.
HQ122780 mRNA. Translation: ADW77414.1.
HQ122801 mRNA. Translation: ADW77433.1.
HQ122805 mRNA. Translation: ADW77435.1.
HQ122808 mRNA. Translation: ADW77438.1.
HQ122813 mRNA. Translation: ADW77442.1.
HQ122839 mRNA. Translation: ADW77465.1.
UniGeneiHs.632482.

Similar proteinsi

Entry informationi

Entry nameiD5K9S8_HUMAN
AccessioniPrimary (citable) accession number: D5K9S8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: August 30, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.