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D5K9S8

- D5K9S8_HUMAN

UniProt

D5K9S8 - D5K9S8_HUMAN

Protein
Submitted name:

POU domain transcription factor OCT4-pg4

Gene

POU5F1P4

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (15 Jun 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    POU domain transcription factor OCT4-pg4Imported
    Gene namesi
    Name:POU5F1P4Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotationSAAS annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiD5K9S8.

    Structurei

    3D structure databases

    ProteinModelPortaliD5K9S8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains POU-specific domain.SAAS annotation
    Contains homeobox DNA-binding domain.SAAS annotation

    Keywords - Domaini

    HomeoboxUniRule annotationSAAS annotation

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR015585. POU_dom_5.
    IPR000327. POU_specific.
    [Graphical view]
    PANTHERiPTHR11636:SF15. PTHR11636:SF15. 1 hit.
    PfamiPF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view]
    PRINTSiPR00028. POUDOMAIN.
    SMARTiSM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D5K9S8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPAFLPPPGG GGDGPGGPEP GWVDPRTWLS FQGPPGGPGI GPGVGSGSEV    50
    WGIPPCPPLY EFCGGMAYCG PQVGVRLVPQ GGLETSQPEG EAGVRVESNS 100
    DGTSLEPCTV PPGAVKLEKE KLEQNPQESQ NIKALQKELE QFAKLLKQKR 150
    ITLGYTQADV GLTLGVLFGK VFSQTTICRF EGLQLSFKNM CKLRPLLQKW 200
    VEEADNNENL QETCKAETLL QARKRKRTSI ENRVRGNLEN LFLQCPKPTL 250
    QQISHIAQQL GLEKDVVRVW FCNRCQKGKQ SSSDYA 286
    Length:286
    Mass (Da):31,159
    Last modified:June 15, 2010 - v1
    Checksum:iA2401689E52BA114
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GU480839 mRNA. Translation: ADE48565.1.
    GU480848 mRNA. Translation: ADE48573.1.
    GU480862 mRNA. Translation: ADE48578.1.
    GU480867 mRNA. Translation: ADE48582.1.
    GU480875 mRNA. Translation: ADE48589.1.
    GU480879 mRNA. Translation: ADE48592.1.
    GU480881 mRNA. Translation: ADE48594.1.
    GU480882 mRNA. Translation: ADE48595.1.
    GU480904 mRNA. Translation: ADE48608.1.
    HQ122676 mRNA. Translation: ADW77328.1.
    HQ122677 mRNA. Translation: ADW77329.1.
    HQ122681 mRNA. Translation: ADW77330.1.
    HQ122687 mRNA. Translation: ADW77334.1.
    HQ122690 mRNA. Translation: ADW77335.1.
    HQ122698 mRNA. Translation: ADW77340.1.
    HQ122700 mRNA. Translation: ADW77342.1.
    HQ122701 mRNA. Translation: ADW77343.1.
    HQ122703 mRNA. Translation: ADW77345.1.
    HQ122704 mRNA. Translation: ADW77346.1.
    HQ122705 mRNA. Translation: ADW77347.1.
    HQ122708 mRNA. Translation: ADW77349.1.
    HQ122709 mRNA. Translation: ADW77350.1.
    HQ122732 mRNA. Translation: ADW77370.1.
    HQ122733 mRNA. Translation: ADW77371.1.
    HQ122734 mRNA. Translation: ADW77372.1.
    HQ122735 mRNA. Translation: ADW77373.1.
    HQ122736 mRNA. Translation: ADW77374.1.
    HQ122740 mRNA. Translation: ADW77378.1.
    HQ122741 mRNA. Translation: ADW77379.1.
    HQ122742 mRNA. Translation: ADW77380.1.
    HQ122743 mRNA. Translation: ADW77381.1.
    HQ122744 mRNA. Translation: ADW77382.1.
    HQ122746 mRNA. Translation: ADW77383.1.
    HQ122748 mRNA. Translation: ADW77384.1.
    HQ122757 mRNA. Translation: ADW77393.1.
    HQ122758 mRNA. Translation: ADW77394.1.
    HQ122760 mRNA. Translation: ADW77396.1.
    HQ122761 mRNA. Translation: ADW77397.1.
    HQ122763 mRNA. Translation: ADW77399.1.
    HQ122764 mRNA. Translation: ADW77400.1.
    HQ122765 mRNA. Translation: ADW77401.1.
    HQ122766 mRNA. Translation: ADW77402.1.
    HQ122767 mRNA. Translation: ADW77403.1.
    HQ122768 mRNA. Translation: ADW77404.1.
    HQ122771 mRNA. Translation: ADW77406.1.
    HQ122772 mRNA. Translation: ADW77407.1.
    HQ122774 mRNA. Translation: ADW77409.1.
    HQ122775 mRNA. Translation: ADW77410.1.
    HQ122778 mRNA. Translation: ADW77412.1.
    HQ122779 mRNA. Translation: ADW77413.1.
    HQ122780 mRNA. Translation: ADW77414.1.
    HQ122801 mRNA. Translation: ADW77433.1.
    HQ122805 mRNA. Translation: ADW77435.1.
    HQ122808 mRNA. Translation: ADW77438.1.
    HQ122813 mRNA. Translation: ADW77442.1.
    HQ122839 mRNA. Translation: ADW77465.1.
    UniGeneiHs.632482.

    Genome annotation databases

    UCSCiuc010pgd.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GU480839 mRNA. Translation: ADE48565.1 .
    GU480848 mRNA. Translation: ADE48573.1 .
    GU480862 mRNA. Translation: ADE48578.1 .
    GU480867 mRNA. Translation: ADE48582.1 .
    GU480875 mRNA. Translation: ADE48589.1 .
    GU480879 mRNA. Translation: ADE48592.1 .
    GU480881 mRNA. Translation: ADE48594.1 .
    GU480882 mRNA. Translation: ADE48595.1 .
    GU480904 mRNA. Translation: ADE48608.1 .
    HQ122676 mRNA. Translation: ADW77328.1 .
    HQ122677 mRNA. Translation: ADW77329.1 .
    HQ122681 mRNA. Translation: ADW77330.1 .
    HQ122687 mRNA. Translation: ADW77334.1 .
    HQ122690 mRNA. Translation: ADW77335.1 .
    HQ122698 mRNA. Translation: ADW77340.1 .
    HQ122700 mRNA. Translation: ADW77342.1 .
    HQ122701 mRNA. Translation: ADW77343.1 .
    HQ122703 mRNA. Translation: ADW77345.1 .
    HQ122704 mRNA. Translation: ADW77346.1 .
    HQ122705 mRNA. Translation: ADW77347.1 .
    HQ122708 mRNA. Translation: ADW77349.1 .
    HQ122709 mRNA. Translation: ADW77350.1 .
    HQ122732 mRNA. Translation: ADW77370.1 .
    HQ122733 mRNA. Translation: ADW77371.1 .
    HQ122734 mRNA. Translation: ADW77372.1 .
    HQ122735 mRNA. Translation: ADW77373.1 .
    HQ122736 mRNA. Translation: ADW77374.1 .
    HQ122740 mRNA. Translation: ADW77378.1 .
    HQ122741 mRNA. Translation: ADW77379.1 .
    HQ122742 mRNA. Translation: ADW77380.1 .
    HQ122743 mRNA. Translation: ADW77381.1 .
    HQ122744 mRNA. Translation: ADW77382.1 .
    HQ122746 mRNA. Translation: ADW77383.1 .
    HQ122748 mRNA. Translation: ADW77384.1 .
    HQ122757 mRNA. Translation: ADW77393.1 .
    HQ122758 mRNA. Translation: ADW77394.1 .
    HQ122760 mRNA. Translation: ADW77396.1 .
    HQ122761 mRNA. Translation: ADW77397.1 .
    HQ122763 mRNA. Translation: ADW77399.1 .
    HQ122764 mRNA. Translation: ADW77400.1 .
    HQ122765 mRNA. Translation: ADW77401.1 .
    HQ122766 mRNA. Translation: ADW77402.1 .
    HQ122767 mRNA. Translation: ADW77403.1 .
    HQ122768 mRNA. Translation: ADW77404.1 .
    HQ122771 mRNA. Translation: ADW77406.1 .
    HQ122772 mRNA. Translation: ADW77407.1 .
    HQ122774 mRNA. Translation: ADW77409.1 .
    HQ122775 mRNA. Translation: ADW77410.1 .
    HQ122778 mRNA. Translation: ADW77412.1 .
    HQ122779 mRNA. Translation: ADW77413.1 .
    HQ122780 mRNA. Translation: ADW77414.1 .
    HQ122801 mRNA. Translation: ADW77433.1 .
    HQ122805 mRNA. Translation: ADW77435.1 .
    HQ122808 mRNA. Translation: ADW77438.1 .
    HQ122813 mRNA. Translation: ADW77442.1 .
    HQ122839 mRNA. Translation: ADW77465.1 .
    UniGenei Hs.632482.

    3D structure databases

    ProteinModelPortali D5K9S8.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi D5K9S8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc010pgd.2. human.

    Miscellaneous databases

    NextBioi 35491865.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR015585. POU_dom_5.
    IPR000327. POU_specific.
    [Graphical view ]
    PANTHERi PTHR11636:SF15. PTHR11636:SF15. 1 hit.
    Pfami PF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view ]
    PRINTSi PR00028. POUDOMAIN.
    SMARTi SM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression of OCT4 Pseudogenes in Human Somatic Tumors."
      Zhao S., Yuan Q., Liu S., Zhang Y., Liu H., Wang F., Liu K., Hao A.
      Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Breast carcinomaImported and GliomaImported.
    2. "Expression of OCT4 pseudogenes in two human somatic tumours: glioma and breast carcinoma."
      Zhao S., Yuan Q., Guo Y., Liu S., Zhang Y., Wang J., Liu H., Wang F., Liu K., Ling E.-A., Hao A.
      Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Breast cancer luminal A subtypeImported, Glioma WHO grade IIImported, Glioma WHO grade IIIImported and Glioma WHO grade IVImported.

    Entry informationi

    Entry nameiD5K9S8_HUMAN
    AccessioniPrimary (citable) accession number: D5K9S8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 15, 2010
    Last sequence update: June 15, 2010
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.