D5K9S8 (D5K9S8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
POU domain transcription factor OCT4-pg4 EMBL ADE48565.1

Gene names

Name:

POU5F1P4 EMBL ADE48565.1

Organism

Homo sapiens (Human) EMBL ADE48565.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU000682.
Sequence similarities	Contains 1 POU-specific domain. Contains 1 homeobox DNA-binding domain. SAAS SAAS013847

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000682 SAAS SAAS013847
Domain	Homeobox RuleBase RU000682 SAAS SAAS013847
Ligand	DNA-binding RuleBase RU000682 SAAS SAAS013847
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D5K9S8 [UniParc]. Last modified June 15, 2010. Version 1. Checksum: A2401689E52BA114	FASTA	286	31,159
	10 20 30 40 50 60 MPAFLPPPGG GGDGPGGPEP GWVDPRTWLS FQGPPGGPGI GPGVGSGSEV WGIPPCPPLY 70 80 90 100 110 120 EFCGGMAYCG PQVGVRLVPQ GGLETSQPEG EAGVRVESNS DGTSLEPCTV PPGAVKLEKE 130 140 150 160 170 180 KLEQNPQESQ NIKALQKELE QFAKLLKQKR ITLGYTQADV GLTLGVLFGK VFSQTTICRF 190 200 210 220 230 240 EGLQLSFKNM CKLRPLLQKW VEEADNNENL QETCKAETLL QARKRKRTSI ENRVRGNLEN 250 260 270 280 LFLQCPKPTL QQISHIAQQL GLEKDVVRVW FCNRCQKGKQ SSSDYA

References

[1]

"Expression of OCT4 Pseudogenes in Human Somatic Tumors." Zhao S., Yuan Q., Liu S., Zhang Y., Liu H., Wang F., Liu K., Hao A. Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Breast carcinoma EMBL ADE48608.1 and Glioma EMBL ADE48589.1.

[2]

"Expression of OCT4 pseudogenes in two human somatic tumours: glioma and breast carcinoma." Zhao S., Yuan Q., Guo Y., Liu S., Zhang Y., Wang J., Liu H., Wang F., Liu K., Ling E.-A., Hao A. Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Breast cancer luminal A subtype EMBL ADW77465.1, Glioma WHO grade II EMBL ADW77370.1, Glioma WHO grade III EMBL ADW77393.1 and Glioma WHO grade IV EMBL ADW77433.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GU480839 mRNA. Translation: ADE48565.1. GU480848 mRNA. Translation: ADE48573.1. GU480862 mRNA. Translation: ADE48578.1. GU480867 mRNA. Translation: ADE48582.1. GU480875 mRNA. Translation: ADE48589.1. GU480879 mRNA. Translation: ADE48592.1. GU480881 mRNA. Translation: ADE48594.1. GU480882 mRNA. Translation: ADE48595.1. GU480904 mRNA. Translation: ADE48608.1. HQ122676 mRNA. Translation: ADW77328.1. HQ122677 mRNA. Translation: ADW77329.1. HQ122681 mRNA. Translation: ADW77330.1. HQ122687 mRNA. Translation: ADW77334.1. HQ122690 mRNA. Translation: ADW77335.1. HQ122698 mRNA. Translation: ADW77340.1. HQ122700 mRNA. Translation: ADW77342.1. HQ122701 mRNA. Translation: ADW77343.1. HQ122703 mRNA. Translation: ADW77345.1. HQ122704 mRNA. Translation: ADW77346.1. HQ122705 mRNA. Translation: ADW77347.1. HQ122708 mRNA. Translation: ADW77349.1. HQ122709 mRNA. Translation: ADW77350.1. HQ122732 mRNA. Translation: ADW77370.1. HQ122733 mRNA. Translation: ADW77371.1. HQ122734 mRNA. Translation: ADW77372.1. HQ122735 mRNA. Translation: ADW77373.1. HQ122736 mRNA. Translation: ADW77374.1. HQ122740 mRNA. Translation: ADW77378.1. HQ122741 mRNA. Translation: ADW77379.1. HQ122742 mRNA. Translation: ADW77380.1. HQ122743 mRNA. Translation: ADW77381.1. HQ122744 mRNA. Translation: ADW77382.1. HQ122746 mRNA. Translation: ADW77383.1. HQ122748 mRNA. Translation: ADW77384.1. HQ122757 mRNA. Translation: ADW77393.1. HQ122758 mRNA. Translation: ADW77394.1. HQ122760 mRNA. Translation: ADW77396.1. HQ122761 mRNA. Translation: ADW77397.1. HQ122763 mRNA. Translation: ADW77399.1. HQ122764 mRNA. Translation: ADW77400.1. HQ122765 mRNA. Translation: ADW77401.1. HQ122766 mRNA. Translation: ADW77402.1. HQ122767 mRNA. Translation: ADW77403.1. HQ122768 mRNA. Translation: ADW77404.1. HQ122771 mRNA. Translation: ADW77406.1. HQ122772 mRNA. Translation: ADW77407.1. HQ122774 mRNA. Translation: ADW77409.1. HQ122775 mRNA. Translation: ADW77410.1. HQ122778 mRNA. Translation: ADW77412.1. HQ122779 mRNA. Translation: ADW77413.1. HQ122780 mRNA. Translation: ADW77414.1. HQ122801 mRNA. Translation: ADW77433.1. HQ122805 mRNA. Translation: ADW77435.1. HQ122808 mRNA. Translation: ADW77438.1. HQ122813 mRNA. Translation: ADW77442.1. HQ122839 mRNA. Translation: ADW77465.1.
IPI	IPI00032965.
UniGene	Hs.632482.
3D structure databases
ProteinModelPortal	D5K9S8.
ModBase	Search...
Proteomic databases
PRIDE	D5K9S8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc010pgd.2. human.
Phylogenomic databases
PhylomeDB	D5K9S8.
Family and domain databases
Gene3D	1.10.10.60. 1 hit. 1.10.260.40. 1 hit.
InterPro	IPR017970. Homeobox_CS. IPR001356. Homeodomain. IPR009057. Homeodomain-like. IPR010982. Lambda_DNA-bd_dom. IPR013847. POU. IPR015585. POU_dom_5. IPR000327. POU_specific. [Graphical view]
PANTHER	PTHR11636:SF15. PTHR11636:SF15. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. PF00157. Pou. 1 hit. [Graphical view]
PRINTS	PR00028. POUDOMAIN.
SMART	SM00389. HOX. 1 hit. SM00352. POU. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit. SSF47413. Lambda_like_DNA. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS00035. POU_1. 1 hit. PS00465. POU_2. 1 hit. PS51179. POU_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35491865.

Entry information

Entry name

D5K9S8_HUMAN

Accession

Primary (citable) accession number: D5K9S8

Entry history

Integrated into UniProtKB/TrEMBL:	June 15, 2010
Last sequence update:	June 15, 2010
Last modified:	April 3, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.