D5K9S7 (D5K9S7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
POU domain transcription factor OCT4-pg3 EMBL ADE48564.1

Gene names

Name:

POU5F1P3 EMBL ADE48564.1

Organism

Homo sapiens (Human) EMBL ADE48564.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 POU-specific domain. SAAS SAAS000327 Contains 1 homeobox DNA-binding domain. SAAS SAAS000327

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS000327
Domain	Homeobox SAAS SAAS000327
Ligand	DNA-binding SAAS SAAS000327
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D5K9S7 [UniParc]. Last modified June 15, 2010. Version 1. Checksum: A1A8E955E7A26AEC	FASTA	186	19,206
	10 20 30 40 50 60 MAGHLASDFA FSPPPGGGGD GPGGPEPGWV DPRTWLSFQG PPGGPGIGPG FGPGSEEWGI 70 80 90 100 110 120 PPCPPPYEFC GGMAYCGPQT GVGLVPQDGL ETSQPEGEAG VGVESNSDGA SPEPCTVPSG 130 140 150 160 170 180 AVKLEKEKLE QNPKESQDIK ALQKELEQFA KLLKQKRITL GYTQADVAHP GGSIWEGVQP NDHLPL

References

[1]	"Expression of OCT4 Pseudogenes in Human Somatic Tumors." Zhao S., Yuan Q., Liu S., Zhang Y., Liu H., Wang F., Liu K., Hao A. Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Breast carcinoma EMBL ADE48605.1 and Glioma EMBL ADE48590.1.
[2]	"Expression of OCT4 pseudogenes in two human somatic tumours: glioma and breast carcinoma." Zhao S., Yuan Q., Guo Y., Liu S., Zhang Y., Wang J., Liu H., Wang F., Liu K., Ling E.-A., Hao A. Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Breast cancer luminal A subtype EMBL ADW77456.1, Glioma WHO grade II EMBL ADW77361.1, Glioma WHO grade III EMBL ADW77389.1 and Glioma WHO grade IV EMBL ADW77425.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GU480838 mRNA. Translation: ADE48564.1. GU480876 mRNA. Translation: ADE48590.1. GU480887 mRNA. Translation: ADE48598.1. GU480892 mRNA. Translation: ADE48600.1. GU480897 mRNA. Translation: ADE48605.1. GU480907 mRNA. Translation: ADE48611.1. HQ122722 mRNA. Translation: ADW77361.1. HQ122724 mRNA. Translation: ADW77363.1. HQ122725 mRNA. Translation: ADW77364.1. HQ122726 mRNA. Translation: ADW77365.1. HQ122728 mRNA. Translation: ADW77367.1. HQ122729 mRNA. Translation: ADW77368.1. HQ122730 mRNA. Translation: ADW77369.1. HQ122753 mRNA. Translation: ADW77389.1. HQ122754 mRNA. Translation: ADW77390.1. HQ122791 mRNA. Translation: ADW77425.1. HQ122792 mRNA. Translation: ADW77426.1. HQ122793 mRNA. Translation: ADW77427.1. HQ122794 mRNA. Translation: ADW77428.1. HQ122795 mRNA. Translation: ADW77429.1. HQ122796 mRNA. Translation: ADW77430.1. HQ122828 mRNA. Translation: ADW77456.1. HQ122829 mRNA. Translation: ADW77457.1. HQ122831 mRNA. Translation: ADW77459.1.
IPI	IPI00915828.
UniGene	Hs.646545.
3D structure databases
ProteinModelPortal	D5K9S7.
ModBase	Search...
Proteomic databases
PRIDE	D5K9S7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc010sgi.2. human.
Family and domain databases
Gene3D	1.10.260.40. 1 hit.
InterPro	IPR010982. Lambda_DNA-bd_dom. IPR015585. POU_dom_5. IPR000327. POU_specific. [Graphical view]
PANTHER	PTHR11636:SF15. PTHR11636:SF15. 1 hit.
Pfam	PF00157. Pou. 1 hit. [Graphical view]
SMART	SM00352. POU. 1 hit. [Graphical view]
SUPFAM	SSF47413. Lambda_like_DNA. 1 hit.
PROSITE	PS51179. POU_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35491864.

Entry information

Entry name

D5K9S7_HUMAN

Accession

Primary (citable) accession number: D5K9S7

Entry history

Integrated into UniProtKB/TrEMBL:	June 15, 2010
Last sequence update:	June 15, 2010
Last modified:	April 3, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.