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D5HCE4 (D5HCE4_SALRM) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length249 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020634

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020634.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124 RuleBase RU004165

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding37 – 448ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding109 – 1124ATP By similarity HAMAP-Rule MF_00124

Sites

Active site1101Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1661Zinc By similarity HAMAP-Rule MF_00124
Metal binding1691Zinc By similarity HAMAP-Rule MF_00124
Metal binding1981Zinc By similarity HAMAP-Rule MF_00124
Metal binding2011Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
D5HCE4 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: B2B328C1781EB24E

FASTA24927,401
        10         20         30         40         50         60 
MQRLRLSPHR AALFMSALEP HIVDRDRTTG WMEVICGSMF SGKTEELIRR LRRARIARQH 

        70         80         90        100        110        120 
TRVFKPALDE RYSEDEVVSH NENSVTTTPV EAPPQIQELV QEADVVGIDE AQFFDDDLVP 

       130        140        150        160        170        180 
TCQALAEDGH RVIVVGLDTD YRAEPFDPMP QLMAVAEHVT KLHAVCVVCG APANHSQRIV 

       190        200        210        220        230        240 
PGEDRVLVGA TEAYEPRCRA CFEPEPVTVT RPRPHTEALR AVATDDADAS TNEADPEAAD 


AASADGTAA 

« Hide

References

« Hide 'large scale' references
[1]"Fine-scale evolution: genomic, phenotypic and ecological differentiation in two coexisting Salinibacter ruber strains."
Pena A., Teeling H., Huerta-Cepas J., Santos F., Yarza P., Brito-Echeverria J., Lucio M., Schmitt-Kopplin P., Meseguer I., Schenowitz C., Dossat C., Barbe V., Dopazo J., Rossello-Mora R., Schuler M., Glockner F.O., Amann R., Gabaldon T., Anton J.
ISME J. -:0-0(2010)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: M8.
[2]"Genome sequence of Salinibacter ruber M8."
Genoscope
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: M8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FP565814 Genomic DNA. Translation: CBH25699.1.
RefSeqYP_003572651.1. NC_014032.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBH25699; CBH25699; SRM_02778.
GeneID8995327.
KEGGsrm:SRM_02778.
PATRIC35493502. VBISalRub49863_2726.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000076390.
KOK00857.

Enzyme and pathway databases

BioCycSRUB761659:GHC6-2816-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5HCE4_SALRM
AccessionPrimary (citable) accession number: D5HCE4
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: June 11, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)