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Protein

6-phosphofructokinase

Gene

pfkA

Organism
Salinibacter ruber (strain M8)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphofructokinase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. fructose 6-phosphate metabolic process Source: InterPro
  2. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, MagnesiumSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSRUB761659:GHC6-2366-MONOMER.
UniPathwayiUPA00109; UER00182.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphofructokinaseSAAS annotation (EC:2.7.1.11SAAS annotation)
Gene namesi
Name:pfkAImported
Ordered Locus Names:SRM_02332Imported
OrganismiSalinibacter ruber (strain M8)Imported
Taxonomic identifieri761659 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidetes Order II. Incertae sedisRhodothermaceaeSalinibacter
ProteomesiUP000000933: Chromosome

Subcellular locationi

Cytoplasm SAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiD5HB48.

Structurei

3D structure databases

ProteinModelPortaliD5HB48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000248869.
KOiK00850.
PhylomeDBiD5HB48.

Family and domain databases

HAMAPiMF_00339. Phosphofructokinase.
InterProiIPR012003. ATP_PFK_prok-type.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamiPF00365. PFK. 1 hit.
[Graphical view]
PIRSFiPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSiPR00476. PHFRCTKINASE.
SUPFAMiSSF53784. SSF53784. 1 hit.
PROSITEiPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5HB48-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPSDSLRVGV LTGGGDCPGI NAALRAVTKS LTLQHDAEVL GFLDGFRGVV
60 70 80 90 100
DRNVEPLHYR DVSGILTRGG TILGASNKAD PFNYLPRGGA DVSAQVMRTY
110 120 130 140 150
RTLDLDALVA IGGDGTMSIA HRLTDLGVDI VGVPKTIDND LVGTDRTVGF
160 170 180 190 200
DTAVSTATDA IDRIHTTAQS HHRVMIVETM GRYSGWIALH AGVASGTDVI
210 220 230 240 250
LLPEIEYEVE TVADVCRDRE RSGQRFTIVA VAEGARRKEG DYVVQERGDE
260 270 280 290 300
YTDSIRLGGI SRVLADQLRE HLDTSIRTTV LGHMQRGGSP TAYDRTLATT
310 320 330 340 350
LGTRAATLVA EGTTGVMVAV QNDAFTQVPL DEIAGKTRTV PLDDPLIASG
360 370
LDVGTSFGVA VSDLSEAASH SKPASPIQP
Length:379
Mass (Da):40,144
Last modified:June 15, 2010 - v1
Checksum:i61A6205E6B33A745
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP565814 Genomic DNA. Translation: CBH25253.1.
RefSeqiYP_003572205.1. NC_014032.1.

Genome annotation databases

EnsemblBacteriaiCBH25253; CBH25253; SRM_02332.
GeneIDi8995079.
KEGGisrm:SRM_02332.
PATRICi35492548. VBISalRub49863_2254.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP565814 Genomic DNA. Translation: CBH25253.1.
RefSeqiYP_003572205.1. NC_014032.1.

3D structure databases

ProteinModelPortaliD5HB48.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiD5HB48.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBH25253; CBH25253; SRM_02332.
GeneIDi8995079.
KEGGisrm:SRM_02332.
PATRICi35492548. VBISalRub49863_2254.

Phylogenomic databases

HOGENOMiHOG000248869.
KOiK00850.
PhylomeDBiD5HB48.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00182.
BioCyciSRUB761659:GHC6-2366-MONOMER.

Family and domain databases

HAMAPiMF_00339. Phosphofructokinase.
InterProiIPR012003. ATP_PFK_prok-type.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamiPF00365. PFK. 1 hit.
[Graphical view]
PIRSFiPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSiPR00476. PHFRCTKINASE.
SUPFAMiSSF53784. SSF53784. 1 hit.
PROSITEiPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Fine-scale evolution: genomic, phenotypic and ecological differentiation in two coexisting Salinibacter ruber strains."
    Pena A., Teeling H., Huerta-Cepas J., Santos F., Yarza P., Brito-Echeverria J., Lucio M., Schmitt-Kopplin P., Meseguer I., Schenowitz C., Dossat C., Barbe V., Dopazo J., Rossello-Mora R., Schuler M., Glockner F.O., Amann R., Gabaldon T., Anton J.
    ISME J. -:0-0(2010)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: M8.
  2. "Genome sequence of Salinibacter ruber M8."
    Genoscope
    Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M8Imported.

Entry informationi

Entry nameiD5HB48_SALRM
AccessioniPrimary (citable) accession number: D5HB48
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: February 4, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.