ID   D5H8I4_SALRM            Unreviewed;       529 AA.
AC   D5H8I4;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=Aldehyde dehydrogenase, mitochondrial {ECO:0000313|EMBL:CBH24339.1};
DE            EC=1.2.1.3 {ECO:0000313|EMBL:CBH24339.1};
GN   OrderedLocusNames=SRM_01418 {ECO:0000313|EMBL:CBH24339.1};
OS   Salinibacter ruber (strain M8).
OC   Bacteria; Rhodothermota; Rhodothermia; Rhodothermales; Salinibacteraceae;
OC   Salinibacter.
OX   NCBI_TaxID=761659 {ECO:0000313|EMBL:CBH24339.1, ECO:0000313|Proteomes:UP000000933};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=M8;
RA   Pena A., Teeling H., Huerta-Cepas J., Santos F., Yarza P.,
RA   Brito-Echeverria J., Lucio M., Schmitt-Kopplin P., Meseguer I.,
RA   Schenowitz C., Dossat C., Barbe V., Dopazo J., Rossello-Mora R.,
RA   Schuler M., Glockner F.O., Amann R., Gabaldon T., Anton J.;
RT   "Fine-scale evolution: genomic, phenotypic and ecological differentiation
RT   in two coexisting Salinibacter ruber strains.";
RL   ISME J. 4:882-95(2010).
RN   [2] {ECO:0000313|EMBL:CBH24339.1, ECO:0000313|Proteomes:UP000000933}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M8 {ECO:0000313|EMBL:CBH24339.1,
RC   ECO:0000313|Proteomes:UP000000933};
RX   PubMed=20164864; DOI=10.1038/ismej.2010.6;
RA   Pena A., Teeling H., Huerta-Cepas J., Santos F., Yarza P.,
RA   Brito-Echeverria J., Lucio M., Schmitt-Kopplin P., Meseguer I.,
RA   Schenowitz C., Dossat C., Barbe V., Dopazo J., Rossello-Mora R.,
RA   Schuler M., Glockner F.O., Amann R., Gabaldon T., Anton J.;
RT   "Fine-scale evolution: genomic, phenotypic and ecological differentiation
RT   in two coexisting Salinibacter ruber strains.";
RL   ISME J. 4:882-895(2010).
RN   [3] {ECO:0000313|Proteomes:UP000000933}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M8 {ECO:0000313|Proteomes:UP000000933};
RG   Genoscope;
RT   "Genome sequence of Salinibacter ruber M8.";
RL   Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FP565814; CBH24339.1; -; Genomic_DNA.
DR   RefSeq; WP_013061759.1; NC_014032.1.
DR   AlphaFoldDB; D5H8I4; -.
DR   KEGG; srm:SRM_01418; -.
DR   PATRIC; fig|761659.10.peg.1556; -.
DR   HOGENOM; CLU_005391_0_2_10; -.
DR   Proteomes; UP000000933; Chromosome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07111; ALDH_F16; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:CBH24339.1}.
FT   DOMAIN          51..492
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   REGION          484..529
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        494..522
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   529 AA;  57550 MW;  2FA812DCDF49E4A5 CRC64;
     MAELEAAPNT ARELLFGDEW EYAPAPQSAD HVRLDDRYGP FIDGEFREVD EYFPSINPAT
     EEPLAEVGLA DEAVVDEAVG AARTAYESHW RDLPGKERAK YIYRIGRMIK EKSREFAVLE
     SMDGGKPIRE SRDMDIPLVA AHFFHYAGWA DKLEYALPGP GRPRSLGVCG QIIPWNFPLL
     MAAWKLAPAL ATGNTVVLKP AETTPLTALK LAEVMQEAGL PPGVVNIVQG AGEVGSALVE
     HPDVDKIAFT GSTGVGKHIQ KQLAGTKKRL TLELGGKGAN IVFEDAPIDQ AVEGIVDGIY
     FNQGHVCCAG SRLLVQESVA EEVTRKLRDR IATLRVGDPL DKNTDIGAIN SKPQLEKIRR
     LVDVGEREGA DKFQPECDLP DDGFWFPPTF FTNVTQSHRI AQEEIFGPVL SVTTFRTPEE
     AVERANNTEY GLASGIWSDK GSKLFSISQA LKSGVVWGNT YNKFDPASPF GGYKESGFGR
     EGGMHGLLPY LERPSQSWQP QTPTNGSPST KPASSTSAGA SPEPKADDT
//