Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

D-ala D-ala ligase C-terminus superfamily

Gene

ddl

Organism
Salinibacter ruber (strain M8)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Mg2+SAAS annotation
  • Mn2+SAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-ala D-ala ligase C-terminus superfamilyImported (EC:6.3.2.4Imported)
Gene namesi
Name:ddlImported
Ordered Locus Names:SRM_01313Imported
OrganismiSalinibacter ruber (strain M8)Imported
Taxonomic identifieri761659 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidetes Order II. Incertae sedisRhodothermaceaeSalinibacter
Proteomesi
  • UP000000933 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

Keywords - Cellular componenti

CytoplasmSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliD5H879.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini114 – 324ATP-graspInterPro annotationAdd BLAST211

Sequence similaritiesi

Belongs to the D-alanine--D-alanine ligase family.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000011592.
KOiK01921.
OMAiQMVEYEV.
OrthoDBiPOG091H00GT.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR011095. Dala_Dala_lig_C.
[Graphical view]
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5H879-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIGLLYDTF DAYSWANDDP PDADAEYEPI ETVDTLAAAV EHLGHTPVRV
60 70 80 90 100
GTAADLRDRL GGGLSLDAAI NITEGAHSRN REAYVPILLE MAGVPCLGSD
110 120 130 140 150
ALTLSVTLDK AWTKDLVAAA DIPTPPHRVY SAPEAVDADD LPGAFPLFVK
160 170 180 190 200
PRYEGTSKGI TPDSKVEDVA ALRGAVDRIT TTYDQDAVAE PFVAGGGEFT
210 220 230 240 250
VAVVGHDPPE ALPVLQRGVE PTTGLGLHVL EHRGAPTADR DWEYELRGTL
260 270 280 290 300
APALEDRLQA LSRRAFDTLD CRDFARADFR VDGDGTPWFL EINPLPTFKP
310 320 330
DDTFAIVAEL MGRDYVDYLA EVFGRGLRRL GLS
Length:333
Mass (Da):36,024
Last modified:June 15, 2010 - v1
Checksum:iFA4B703FBB34025D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP565814 Genomic DNA. Translation: CBH24234.1.
RefSeqiWP_013061666.1. NC_014032.1.

Genome annotation databases

EnsemblBacteriaiCBH24234; CBH24234; SRM_01313.
KEGGisrm:SRM_01313.
PATRICi35490448. VBISalRub49863_1223.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP565814 Genomic DNA. Translation: CBH24234.1.
RefSeqiWP_013061666.1. NC_014032.1.

3D structure databases

ProteinModelPortaliD5H879.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBH24234; CBH24234; SRM_01313.
KEGGisrm:SRM_01313.
PATRICi35490448. VBISalRub49863_1223.

Phylogenomic databases

HOGENOMiHOG000011592.
KOiK01921.
OMAiQMVEYEV.
OrthoDBiPOG091H00GT.

Enzyme and pathway databases

UniPathwayiUPA00219.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR011095. Dala_Dala_lig_C.
[Graphical view]
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD5H879_SALRM
AccessioniPrimary (citable) accession number: D5H879
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: November 30, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.