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D5H6C9 (D5H6C9_SALRM) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length465 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site991Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site3261Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1961Substrate By similarity HAMAP-Rule MF_01201
Binding site3741Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue991N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D5H6C9 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: 3A63DD4326E1328B

FASTA46548,585
        10         20         30         40         50         60 
MPVDSTGRGP VGCEAGGRGE HVRRAIGAGS FGNHRPGRRL SCACSLIFAR SPVPFAIDRS 

        70         80         90        100        110        120 
PHTVGAAPVT ATVDLAAIQH NAGVLQERAG GADVMAIIKA DAYGHGVRPV ARAAYEAGIR 

       130        140        150        160        170        180 
HYGVARLPEG VHLREAGHGG RILVLGAPAP TQLPRYAEYD LDLTVPSADI AAAVVRHASP 

       190        200        210        220        230        240 
EAPLRVHVTV DTGMGRLGLA PDDVPAVMTR LADAPGVRLA GLWTHFATAD APGSSFAQTQ 

       250        260        270        280        290        300 
LDRFRAVVDA VDVDVEHVHA ANTGGLLTIG APTHEFDASL VRSGIALYGL AATPELSARL 

       310        320        330        340        350        360 
DLRPAMRLAA RVTHLKTVPA GTPISYGAQW EAPRRTRIAT LGIGYGDGYP RRCSGRASVR 

       370        380        390        400        410        420 
IGGASCPIVG TICMDMCMVD LGPPNEAPAT RVDRGDEAVL FGPAGPTAYD VAQWSDTIPY 

       430        440        450        460 
EILCGVSPRV PRRHVNCTDE NGTDENGTDD MRAPSRLTRP TASGG 

« Hide

References

« Hide 'large scale' references
[1]"Fine-scale evolution: genomic, phenotypic and ecological differentiation in two coexisting Salinibacter ruber strains."
Pena A., Teeling H., Huerta-Cepas J., Santos F., Yarza P., Brito-Echeverria J., Lucio M., Schmitt-Kopplin P., Meseguer I., Schenowitz C., Dossat C., Barbe V., Dopazo J., Rossello-Mora R., Schuler M., Glockner F.O., Amann R., Gabaldon T., Anton J.
ISME J. -:0-0(2010)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: M8.
[2]"Genome sequence of Salinibacter ruber M8."
Genoscope
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: M8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FP565814 Genomic DNA. Translation: CBH23584.1.
RefSeqYP_003570537.1. NC_014032.1.

3D structure databases

ProteinModelPortalD5H6C9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBH23584; CBH23584; SRM_00663.
GeneID8994114.
KEGGsrm:SRM_00663.
PATRIC35489224. VBISalRub49863_0619.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.
PhylomeDBD5H6C9.

Enzyme and pathway databases

BioCycSRUB761659:GHC6-671-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5H6C9_SALRM
AccessionPrimary (citable) accession number: D5H6C9
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: July 9, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)