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D5H3J5 (D5H3J5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:HLA-B EMBL CBL53180.1
OrganismHomo sapiens (Human) EMBL CBL53180.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the presentation of foreign antigens to the immune system By similarity. SAAS SAAS027648

Sequence similarities

Belongs to the MHC class I family. RuleBase RU004439

Contains Ig-like C1-type (immunoglobulin-like) domain. SAAS SAAS027648

Sequences

Sequence LengthMass (Da)Tools
D5H3J5 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: E45C71FDEFC628AD

FASTA36240,481
        10         20         30         40         50         60 
MRVTAPRTLL LLLWGAVALT ETWAGSHSMR YFYTAMSRPG RGEPRFITVG YVDDTLFVRF 

        70         80         90        100        110        120 
DSDATSPRKE PRAPWIEQEG PEYWDRETQI SKTNTQTYRE NLRTALRYYN QSEAGSHIIQ 

       130        140        150        160        170        180 
RMYGCDVGPD GRLLRGYDQD AYDGKDYIAL NEDLSSWTAA DTAAQITQRK WEAARVAEQD 

       190        200        210        220        230        240 
RAYLEGLCVE SLRRYLENGK ETLQRADPPK THVTHHPISD HEVTLRCWAL GFYPAEITLT 

       250        260        270        280        290        300 
WQRDGEDQTQ DTELVETRPA GDRTFQKWAA VVVPSGEEQR YTCHVQHEGL PKPLTLRWEP 

       310        320        330        340        350        360 
SSQSTVPIVG IVAGLAVLAV VVIGAVVAAV MCRRKSSGGK GGSYSQAACS DSAQGSDVSL 


TA 

« Hide

References

[1]"A NEW SYNONYMOUS B*4402 ALLELE DEMONSTRATES THE RELEVANCE OF EFI STANDARD NR L1.4100: ANNEALING POSITION OF PRIMERS MUST BE DEFINED."
Jongsma T.W., Lems S.P.M., Hepkema B.G.
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[2]Hepkema B.
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Characterization and polymorphism analyses of HLA-B genomic full length in Chinese Han population."
Xu Y., Deng Z., Yang B.
Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[4]"New B*44:02 Allele Variant."
Serov Y.A., Hommel-Berrey G.A., House K.D., Arnoff T.S., Lobashevsky A.L.
Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[5]"New HLA class I alleles containing non-coding haplotype-specific SNPs."
Sayer D.C., Alizadeh M., Hogan H.M., Senitzer D., Gendzekhadze K., Humphreys I.
Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[6]"Phase-defined complete sequencing of the HLA genes by next-generation sequencing."
Hosomichi K., Jinam T.A., Mitsunaga S., Nakaoka H., Inoue I.
BMC Genomics 14:355-355(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[7]"The novel HLA-B*44:02:27 allele, identified by sequencing-based typing of a candidate stem-cell donor."
van Soest M., Rosel M., de Graaff A., Zwan B., Spierings E.
Tissue Antigens 81:230-231(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[8]"Confirmatory sequencing of HLA-B*44:02:01:01."
McWhinnie A.J., Robinson J.
Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Saliva collection EMBL CDK41207.1.
[9]"Confirmatory sequencing of HLA-B*44:02:01:03."
McWhinnie A.J., Robinson J.
Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Peripheral blood EMBL CDO58211.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HM595428 Genomic DNA. Translation: ADQ48112.1.
HQ693697 Genomic DNA. Translation: AEF97826.1.
JX196202 Genomic DNA. Translation: AFM91112.1.
JX564251 Genomic DNA. Translation: AGI65158.1.
AB774993 Genomic DNA. Translation: BAN59839.1.
FN796495 Genomic DNA. Translation: CBL53180.1.
HG794398 Genomic DNA. Translation: CDK41207.1.
HG970094 Genomic DNA. Translation: CDO58211.1.
UniGeneHs.654404.
Hs.77961.

3D structure databases

ProteinModelPortalD5H3J5.
SMRD5H3J5. Positions 25-300.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

OMACEGEANP.
PhylomeDBD5H3J5.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
IPR010579. MHC_I_a_C.
[Graphical view]
PfamPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
PF06623. MHC_I_C. 1 hit.
[Graphical view]
PRINTSPR01638. MHCCLASSI.
SMARTSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMSSF54452. SSF54452. 1 hit.
PROSITEPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSHLA-B. human.
NextBio35491803.

Entry information

Entry nameD5H3J5_HUMAN
AccessionPrimary (citable) accession number: D5H3J5
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: July 9, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.