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Protein

Elongation factor Tu

Gene

tufA

Organism
Lactobacillus crispatus (strain ST1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi20 – 27GTPUniRule annotation8
Nucleotide bindingi82 – 86GTPUniRule annotation5
Nucleotide bindingi137 – 140GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufAImported
Synonyms:tufUniRule annotation
Ordered Locus Names:LCRIS_00865Imported
OrganismiLactobacillus crispatus (strain ST1)Imported
Taxonomic identifieri748671 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000002371 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi748671.LCRIS_00865

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 205Tr-type GInterPro annotationAdd BLAST195

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV Bacteria
COG0050 LUCA
HOGENOMiHOG000229290
KOiK02358
OMAiAIRDMGM
OrthoDBiPOG091H00LA

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

D5H2S7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKEHYVRT KPHVNIGTIG HVDHGKTTLT AAITTVLADK GLAKAEDYSQ
60 70 80 90 100
IDAAPEEKER GITINTAHVE YETENRHYAH MDAPGHADYI KNMITGAAQM
110 120 130 140 150
DGAILVVAAT DGPMPQTREH ILLARQVGVN YIVVFLNKCD LVDDPELIDL
160 170 180 190 200
VEMEVRDLLT EYDYPGDDIP VVRGSALKAL QGDKEAQEQI LKLMDVVDEY
210 220 230 240 250
IPTPERQTDK PFLMPVEDVF TITGRGTVAS GRIDRGTVKV GDEVEIVGLV
260 270 280 290 300
DKVLKSVVTG LEMFHKTLDL GEAGDNVGVL LRGIDRDQVV RGQVLAAPGS
310 320 330 340 350
IQTHKEFKGQ VYILKKEEGG RHTPFFSDYR PQFYFHTTDI TGEIELPEGT
360 370 380 390
EMVMPGDNTE FTVKLIKPAA IEKGTKFTIR EGGRTVGAGQ VTEILD
Length:396
Mass (Da):43,604
Last modified:June 15, 2010 - v1
Checksum:i97D73EC2AEE0376D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN692037 Genomic DNA Translation: CBL50312.1
RefSeqiWP_013086177.1, NC_014106.1

Genome annotation databases

EnsemblBacteriaiCBL50312; CBL50312; LCRIS_00865
GeneIDi9106266
KEGGilcr:LCRIS_00865

Similar proteinsi

Entry informationi

Entry nameiD5H2S7_LACCS
AccessioniPrimary (citable) accession number: D5H2S7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: May 23, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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