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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus crispatus (strain ST1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei575UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciLCRI748671:G1GKG-1995-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:LCRIS_01981Imported
OrganismiLactobacillus crispatus (strain ST1)Imported
Taxonomic identifieri748671 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000002371 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiD5H069

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi748671.LCRIS_01981

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili47 – 67Sequence analysisAdd BLAST21
Coiled coili362 – 382Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

D5H069-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVKKLENNS DVNVVAEESK VLTNLLNEST KQVIGQAAFD KIQNLIKISA
60 70 80 90 100
AKDYQELEKQ IASLNNREMI VVARYFATLP LLINISEDVE LASKVNVLNN
110 120 130 140 150
THQDYLGKLS DTIDIVAQKK NAEEILEHVN VVPVLTAHPT QVQRKTILEL
160 170 180 190 200
TDQIHQLLRN YRDVKNGTID RDEWTEQMRA CIEILMQTDI IRGHKLKVAN
210 220 230 240 250
EITNVLAYYP KALIPAITKF TSRYKELAKK HGLNASHATP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAD TLELSATLQS QVIFEYYIKQ INKLYRAISM STSYMEPSDD
310 320 330 340 350
VMHLSELSND DSPFRTNEPY RRAFYYIQSR LVHTEQKLLN ITNKNTFLKK
360 370 380 390 400
RDLQNLDKIP CYQNAQEFKA DLEIIKNSLE EDHDHAVVDS YFTQILEAIN
410 420 430 440 450
IFGFHLATID MRQDSSVNEA CVAELLKSAG ICDNYSDLSE DKKIKLLLNE
460 470 480 490 500
LNNDPRNLHA NNKPKSELLQ KELKIYKTAR QLKDRLGEDV IKQHIISHTE
510 520 530 540 550
SVSDMLEQAI MLKEYDLLDN QKARIQVVPL FETVEDLNNA REIIKEFLSF
560 570 580 590 600
DIVKKWLVSQ NNYQEVMLGY SDSNKDGGYL ASCWNLYKAQ KDLTKIGEEM
610 620 630 640 650
GIKITFMHGR GGTVGRGGGP SYEAITAQPF KSINDRMRMT EQGEIIQNKY
660 670 680 690 700
GNKDTAYYNL EMLASATIDR MASKQIVSED HVADFRSSMD QIVAKSNEVY
710 720 730 740 750
RKLVFENPNF LKYFFQATPI KEISGLNVGS RPASRKKLTD FSGLRAIPWV
760 770 780 790 800
FSWSQSRVMF PGWYGVGSGF KSFIDADPAN LKELQNMYQG WPFFHSLLSN
810 820 830 840 850
VDMVLSKSNM RIAKQYADLC EDEQIKSVFD IINQEWELTK KVILQIEGHD
860 870 880 890 900
ELIEDAPTLK KSLEYRMPYF NILNYIQLEM IKRDREDEIQ GVYQSIIPIT
910
INGVASGLRN SG
Length:912
Mass (Da):104,429
Last modified:June 15, 2010 - v1
Checksum:iCC7A8A588E95EE1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN692037 Genomic DNA Translation: CBL51428.1
RefSeqiWP_013087066.1, NC_014106.1

Genome annotation databases

EnsemblBacteriaiCBL51428; CBL51428; LCRIS_01981
GeneIDi9106970
KEGGilcr:LCRIS_01981
PATRICifig|748671.3.peg.1941

Similar proteinsi

Entry informationi

Entry nameiD5H069_LACCS
AccessioniPrimary (citable) accession number: D5H069
Entry historyiIntegrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: March 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported