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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus crispatus (strain ST1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei575 – 5751UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciLCRI748671:GIX1-2055-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:LCRIS_01981Imported
OrganismiLactobacillus crispatus (strain ST1)Imported
Taxonomic identifieri748671 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000002371 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi748671.LCRIS_01981.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5H069-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVKKLENNS DVNVVAEESK VLTNLLNEST KQVIGQAAFD KIQNLIKISA
60 70 80 90 100
AKDYQELEKQ IASLNNREMI VVARYFATLP LLINISEDVE LASKVNVLNN
110 120 130 140 150
THQDYLGKLS DTIDIVAQKK NAEEILEHVN VVPVLTAHPT QVQRKTILEL
160 170 180 190 200
TDQIHQLLRN YRDVKNGTID RDEWTEQMRA CIEILMQTDI IRGHKLKVAN
210 220 230 240 250
EITNVLAYYP KALIPAITKF TSRYKELAKK HGLNASHATP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAD TLELSATLQS QVIFEYYIKQ INKLYRAISM STSYMEPSDD
310 320 330 340 350
VMHLSELSND DSPFRTNEPY RRAFYYIQSR LVHTEQKLLN ITNKNTFLKK
360 370 380 390 400
RDLQNLDKIP CYQNAQEFKA DLEIIKNSLE EDHDHAVVDS YFTQILEAIN
410 420 430 440 450
IFGFHLATID MRQDSSVNEA CVAELLKSAG ICDNYSDLSE DKKIKLLLNE
460 470 480 490 500
LNNDPRNLHA NNKPKSELLQ KELKIYKTAR QLKDRLGEDV IKQHIISHTE
510 520 530 540 550
SVSDMLEQAI MLKEYDLLDN QKARIQVVPL FETVEDLNNA REIIKEFLSF
560 570 580 590 600
DIVKKWLVSQ NNYQEVMLGY SDSNKDGGYL ASCWNLYKAQ KDLTKIGEEM
610 620 630 640 650
GIKITFMHGR GGTVGRGGGP SYEAITAQPF KSINDRMRMT EQGEIIQNKY
660 670 680 690 700
GNKDTAYYNL EMLASATIDR MASKQIVSED HVADFRSSMD QIVAKSNEVY
710 720 730 740 750
RKLVFENPNF LKYFFQATPI KEISGLNVGS RPASRKKLTD FSGLRAIPWV
760 770 780 790 800
FSWSQSRVMF PGWYGVGSGF KSFIDADPAN LKELQNMYQG WPFFHSLLSN
810 820 830 840 850
VDMVLSKSNM RIAKQYADLC EDEQIKSVFD IINQEWELTK KVILQIEGHD
860 870 880 890 900
ELIEDAPTLK KSLEYRMPYF NILNYIQLEM IKRDREDEIQ GVYQSIIPIT
910
INGVASGLRN SG
Length:912
Mass (Da):104,429
Last modified:June 15, 2010 - v1
Checksum:iCC7A8A588E95EE1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN692037 Genomic DNA. Translation: CBL51428.1.
RefSeqiWP_013087066.1. NC_014106.1.

Genome annotation databases

EnsemblBacteriaiCBL51428; CBL51428; LCRIS_01981.
GeneIDi9106970.
KEGGilcr:LCRIS_01981.
PATRICi37242773. VBILacCri149433_1941.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN692037 Genomic DNA. Translation: CBL51428.1.
RefSeqiWP_013087066.1. NC_014106.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi748671.LCRIS_01981.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBL51428; CBL51428; LCRIS_01981.
GeneIDi9106970.
KEGGilcr:LCRIS_01981.
PATRICi37242773. VBILacCri149433_1941.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Enzyme and pathway databases

BioCyciLCRI748671:GIX1-2055-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ST1Imported.
  2. "Genome Sequence of Lactobacillus crispatus ST1."
    Ojala T., Kuparinen V., Koskinen J.P., Alatalo E., Holm L., Auvinen P., Edelman S., Westerlund-Wikstroem B., Korhonen T.K., Paulin L., Kankainen M.
    Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ST1.

Entry informationi

Entry nameiD5H069_LACCS
AccessioniPrimary (citable) accession number: D5H069
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: July 22, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.