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Protein

Guanylate kinase

Gene

gmk1

Organism
Lactobacillus crispatus (strain ST1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmk1Imported
Synonyms:gmkUniRule annotation
Ordered Locus Names:LCRIS_01334Imported
OrganismiLactobacillus crispatus (strain ST1)Imported
Taxonomic identifieri748671 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000002371 Componenti: Chromosome

Subcellular locationi

D5GYC2:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi748671.LCRIS_01334.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 184Guanylate kinase-likeInterPro annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
HOGENOMiHOG000037639.
KOiK00942.
OMAiYGTLKSE.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D5GYC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADKGLLLVL SGPSGVGKGT VKSAIVENKV FPFEYSVSMT TRQPRPGEVN
60 70 80 90 100
GQDYFFVSED RFQEAIKNGE LLEYNKYVGH YYGTPLAPVK KMLHDGKDVL
110 120 130 140 150
LEIDVNGAQK VREKMPDGVF IFLTPPDLHT LHLRLEHRGT ESEDVICGRI
160 170 180 190 200
KQARNEILEM EDYDYAVVND TVANAVDHIK AIVDAEHVSV KRVIDDYRKM

VKED
Length:204
Mass (Da):23,023
Last modified:June 15, 2010 - v1
Checksum:iB64106C8B51E4494
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN692037 Genomic DNA. Translation: CBL50781.1.
RefSeqiWP_013086536.1. NC_014106.1.

Genome annotation databases

EnsemblBacteriaiCBL50781; CBL50781; LCRIS_01334.
GeneIDi9107685.
KEGGilcr:LCRIS_01334.
PATRICifig|748671.3.peg.1308.

Similar proteinsi

Entry informationi

Entry nameiD5GYC2_LACCS
AccessioniPrimary (citable) accession number: D5GYC2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: September 27, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported