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D5GH50

- D5GH50_TUBMM

UniProt

D5GH50 - D5GH50_TUBMM

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Protein

DNA ligase

Gene

GSTUM_00007703001

Organism
Tuber melanosporum (strain Mel28) (Perigord black truffle)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:GSTUM_00007703001Imported
OrganismiTuber melanosporum (strain Mel28) (Perigord black truffle)Imported
Taxonomic identifieri656061 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaPezizomycetesPezizalesTuberaceaeTuber
ProteomesiUP000006911: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliD5GH50.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiD5GH50.
KOiK10777.
OMAiHMCPSTK.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5GH50-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDIDDIDLP DIPRAPVDPS GDTFGPNVIL SDSDLDKAYP NRPRNKNPTL
60 70 80 90 100
PFADLYLSLF EPLLANKKKR TGVSIRGTNK VLKPHEIRRN IIDRFISRWR
110 120 130 140 150
NEVGNDIYPT LRLILCEKDR DRSVYHLKEK TIGRLLVKVM KINKDSDDGY
160 170 180 190 200
SLINWKQPGT SKSAGDFALR CYEIIRKRPM RTTPGSLTIS QVNSMLDRLS
210 220 230 240 250
LASKEEEQLP IMTEFYNNMN ASELMWLIRI IMRQMKVGAT ERTFFDAWHP
260 270 280 290 300
DAAALFNISS SLKRVCWELS DPEFRMDSDG KSVSLMSCFQ PQLAQFQKRS
310 320 330 340 350
LDDAVKAMHL TPEDPIFWIE EKLDGERMQM HYENGNFMFW SRKAKDYTRL
360 370 380 390 400
YGSCFDDGSL TRHLRGAFDD GVKSIILDGE MITWDPRLDC IVAFGTLKTA
410 420 430 440 450
ALEGIRNPFG DGPRPLFKVF DILHLNGGCL INYSLRDRRM ALERSVKTID
460 470 480 490 500
RRMEVHKYEE AREAVEIERA LRKVIAEASE GLVIKNPRSI YRLNDRNDDW
510 520 530 540 550
MKVKPEYMTE FGESLDLVVL GGYWGSGTRG GILSSYLCGL RVDGNHLKPG
560 570 580 590 600
EDPMKFRSFC KVGGGFTAND YSKIAHMTDS QWVPWDPKKP PSEHIEIVAG
610 620 630 640 650
GRGVDQPDVW IRPDKSIVLE VKAASIVPTD EFRVGKSLRF PRFRQIREDK
660 670 680 690 700
DWQTALSISE LIALKEEVEK EKADEEKRIE VENRTRRAGK RMKREYTVLG
710 720 730 740 750
ASDKPADFVS PTVEGGPRLF EGRSFYVMSD ATTPKKMGKA EVEQLIKSHG
760 770 780 790 800
GNLYQTENAV PDTNVIGDKN NVKISALKKK GTHDVIRPAW IFDCIRQHEL
810 820 830 840 850
DLQRGQKGCY IIPIEARHIL HAASGVERRA AASVDQFGDS YARDLTMEEI
860 870 880 890 900
SNLLRDMPGA FDRTFASEFV KGLSEHDQRE LGELPGWMFK TFVIYVDREG
910 920 930 940 950
QGEVNENLKP SPLLALFAGA RIALDLQDTE ITHIIASHDQ QRLHELREAI
960 970 980 990
KWRPRIPRIV TRDWLKSSLE ARTVLDEEQF SPALGCVTGS A
Length:991
Mass (Da):113,000
Last modified:June 15, 2010 - v1
Checksum:iF9AB8C6AA89EBB71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN430297 Genomic DNA. Translation: CAZ83843.1.
RefSeqiXP_002839652.1. XM_002839606.1.
UniGeneiTme.2866.

Genome annotation databases

EnsemblFungiiCAZ83843; CAZ83843; GSTUM_00007703001.
GeneIDi9185097.
KEGGitml:GSTUM_00007703001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN430297 Genomic DNA. Translation: CAZ83843.1 .
RefSeqi XP_002839652.1. XM_002839606.1.
UniGenei Tme.2866.

3D structure databases

ProteinModelPortali D5GH50.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CAZ83843 ; CAZ83843 ; GSTUM_00007703001 .
GeneIDi 9185097.
KEGGi tml:GSTUM_00007703001.

Phylogenomic databases

InParanoidi D5GH50.
KOi K10777.
OMAi HMCPSTK.
OrthoDBi EOG7QC84G.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
PANTHERi PTHR10459:SF7. PTHR10459:SF7. 1 hit.
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Mel28Imported.

Entry informationi

Entry nameiD5GH50_TUBMM
AccessioniPrimary (citable) accession number: D5GH50
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: October 29, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3