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Protein

Histone-lysine N-methyltransferase

Gene

GSTUM_00006511001

Organism
Tuber melanosporum (strain Mel28) (Perigord black truffle)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N6-methyl-L-lysine-[histone].PROSITE-ProRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferasePROSITE-ProRule annotation (EC:2.1.1.43PROSITE-ProRule annotation)
Gene namesi
ORF Names:GSTUM_00006511001Imported
OrganismiTuber melanosporum (strain Mel28) (Perigord black truffle)Imported
Taxonomic identifieri656061 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaPezizomycetesPezizalesTuberaceaeTuber
Proteomesi
  • UP000006911 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi39416.CAZ82931

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini133 – 187AWSInterPro annotationAdd BLAST55
Domaini189 – 306SETInterPro annotationAdd BLAST118
Domaini313 – 329Post-SETInterPro annotationAdd BLAST17

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili627 – 677Sequence analysisAdd BLAST51
Coiled coili763 – 783Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoidiD5GEI8
KOiK11423
OMAiCYVDKWV
OrthoDBiEOG092C3T9B

Family and domain databases

Gene3Di1.10.1740.100, 1 hit
InterProiView protein in InterPro
IPR006560 AWS_dom
IPR025788 Hist-Lys_N-MeTrfase_SET2_fun
IPR003616 Post-SET_dom
IPR001214 SET_dom
IPR013257 SRI
IPR038190 SRI_sf
PfamiView protein in Pfam
PF00856 SET, 1 hit
PF08236 SRI, 1 hit
SMARTiView protein in SMART
SM00570 AWS, 1 hit
SM00317 SET, 1 hit
PROSITEiView protein in PROSITE
PS51215 AWS, 1 hit
PS50868 POST_SET, 1 hit
PS51568 SAM_MT43_SET2_1, 1 hit
PS50280 SET, 1 hit

Sequencei

Sequence statusi: Complete.

D5GEI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAGTINGSP SPGSEGVRNI HLSDSPRCGS AGVGRHSRVT VPDELKMRAS
60 70 80 90 100
RGSSKASSRG NTPSSQGSEV SVKQGNGTPP RKSQRAAPQK SARKPPTLFT
110 120 130 140 150
DYPDSTQEAI STFSVIDECI YSTKSIGDSG QDGEVMSCEC RTDWDGECNP
160 170 180 190 200
ACGDNSDCIN RMTSMECTQD DRACGQDCQN QRFQQRQYAD VSVIKTEKKG
210 220 230 240 250
FGLRANSDIS INTFLYEYVG EVIDENKFRR RMEKYDSEGI KHFYFMSLGK
260 270 280 290 300
NEFIDATKKG GLARFCNHSC NPNCFIDKWV VGEKLRMGIF AKRNVKAGEE
310 320 330 340 350
LVFDYNVDRY GAEPQTCYCG EFNCLGYIGG KTQTDGAAPK LSHHIIEALG
360 370 380 390 400
LEDSEEWSTA TAKKGRRLKK TDGDDEDYVE SVQSKPLGEA DVTKVMSSLL
410 420 430 440 450
HCKEKWIVSK LLHRIQLSED EAVPARVVKM HGYQIMGKIL HDYQSDENIV
460 470 480 490 500
LMALDILMKF PRITKNKITS SKIEPTVQQL STADDQRVQE ASKALLEVWS
510 520 530 540 550
SLETGFRIPR RSKADMERTR SMYQAYERES SSKSKSNSPQ LEKPLTPNGP
560 570 580 590 600
SRPRPFTKSG FQNQPPRGPR AEQFQRHNDK PRRDIPWGWH KTHTGDGKLY
610 620 630 640 650
YYSNDGRARW DIPQEPSLQA IIDGITRSRS TEKMNKQEQE RLKEEERVRQ
660 670 680 690 700
AEKEADSKRA KEMLKEKEKA QREAEKIKPP KIYDNEKTKK ILIRAFSTVV
710 720 730 740 750
ANAVNKYESE IGGRDLVKKH AKDITELLVK KEMKDGRQIA NPHLLLESDS
760 770 780 790 800
KRLKVKGFVK PYIEKVIRNK QSMDNRKREK QKASSSSHRP ESSSSSEKNK
810 820 830 840 850
EVASESSFIP PAAISPMADG VETSIGTPMA GTTPLATPGK RRRDEIGEAS
860 870 880 890
GNPDVVAENE GGDPKRPRPS PPKDVTPPPP PTGVTEVTFS SS
Length:892
Mass (Da):99,799
Last modified:June 15, 2010 - v1
Checksum:i7852D2EE354FE766
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN430175 Genomic DNA Translation: CAZ82931.1
RefSeqiXP_002838740.1, XM_002838694.1
UniGeneiTme.3754

Genome annotation databases

EnsemblFungiiCAZ82931; CAZ82931; GSTUM_00006511001
GeneIDi9181562
KEGGitml:GSTUM_00006511001

Entry informationi

Entry nameiD5GEI8_TUBMM
AccessioniPrimary (citable) accession number: D5GEI8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: March 28, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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