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Protein
Submitted name:

Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase

Gene

PRU_0131

Organism
Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

pyridoxal 5'-phosphateSAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseSAAS annotationImported, LigaseImported

Keywords - Ligandi

Pyridoxal phosphateSAAS annotation

Enzyme and pathway databases

BioCyciPRUM264731:GHX6-130-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligaseImported (EC:5.1.1.1Imported, EC:6.3.2.10Imported)
Gene namesi
Ordered Locus Names:PRU_0131Imported
OrganismiPrevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23)Imported
Taxonomic identifieri264731 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPrevotellaceaePrevotella
ProteomesiUP000000927 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi264731.PRU_0131.

Structurei

3D structure databases

ProteinModelPortaliD5EVJ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000274965.
KOiK01775.
OMAiEPEIYSF.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.1190.10. 1 hit.
3.40.1390.10. 1 hit.
3.90.190.20. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR029066. PLP-binding_barrel.
IPR005863. UDP-N-AcMur_synth.
[Graphical view]
PANTHERiPTHR23135:SF3. PTHR23135:SF3. 1 hit.
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF01225. Mur_ligase. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
SSF63418. SSF63418. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

D5EVJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTDSRSLCF PEETLFFALK TQRNDGHRYI QDLYNRGVRQ FVVEQVPEAY
60 70 80 90 100
ETLYPQANFL RVPHTLAALQ RLAERHRDEF SLPIVGITGS NGKTMVKEWL
110 120 130 140 150
YQLLLPSQRI VRSPRSYNSQ IGVPLSVWLL NEQTEVGIFE AGISQPGEMM
160 170 180 190 200
ALRDIIQPTI GVLTSLGAAH QENFRSMEEK CMEKLELMHD TEAMVYCSDN
210 220 230 240 250
DIVSRCIRRM NYKGEKISWS TCDQQAAFYV KSVENSHITY IWKEEENCFD
260 270 280 290 300
IPFIDEASIE DCITCAAVAL RLGLTPGDLA DRMPKLEPVA MRLEVKEGQR
310 320 330 340 350
GCILINDSYN SDINSLDIAL DFMNRREELK KRTLILSDMF QSGLSPEKLY
360 370 380 390 400
AQVSELAVKR GITKFIGIGA QLTAQADKIQ IADKQFFADV NHFLGSDAFT
410 420 430 440 450
GLRNEMILLK GARPFGFDQI TEQLEQKVHE TILEVNLNAV VENLNYYRSF
460 470 480 490 500
MKPETKMVCM IKADAYGAGA VEIAKTLQDH RVDYLAVAVA DEGVTLRKAG
510 520 530 540 550
ITANIMIMNP EMTAFKTMFD YDLEPEVYSF RLLDALIKAA RKEGITGWPV
560 570 580 590 600
HIKLDTGMHR LGFDPEQDMD ELIDRLTHQQ AVIPRSVFSH FVGSDSDDFD
610 620 630 640 650
NFSTLQFKRF EMGSQKLQAA FSHKILRHID NSAGIEHFPD RQLDMCRLGL
660 670 680 690 700
GLYGIDSRDN RILHTVSTLK TTILQMHQVP KSETVGYSRK GKLTRDSVIA
710 720 730 740 750
AIPIGYADGL NRRLGNRHCY CLVNGQKAEY VGNICMDVAL IDVTDIPCQE
760 770 780 790
GDQVEIFGEH LPVTVLSDVL ETIPYEVLTG ISNRVKRVYF QD
Length:792
Mass (Da):89,764
Last modified:June 15, 2010 - v1
Checksum:i9B66040B7B1BD3EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002006 Genomic DNA. Translation: ADE81691.1.
RefSeqiWP_013063678.1. NC_014033.1.
YP_003573533.1. NC_014033.1.

Genome annotation databases

EnsemblBacteriaiADE81691; ADE81691; PRU_0131.
KEGGipru:PRU_0131.
PATRICi35494427. VBIPreRum14515_0128.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002006 Genomic DNA. Translation: ADE81691.1.
RefSeqiWP_013063678.1. NC_014033.1.
YP_003573533.1. NC_014033.1.

3D structure databases

ProteinModelPortaliD5EVJ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264731.PRU_0131.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADE81691; ADE81691; PRU_0131.
KEGGipru:PRU_0131.
PATRICi35494427. VBIPreRum14515_0128.

Phylogenomic databases

HOGENOMiHOG000274965.
KOiK01775.
OMAiEPEIYSF.

Enzyme and pathway databases

BioCyciPRUM264731:GHX6-130-MONOMER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.1190.10. 1 hit.
3.40.1390.10. 1 hit.
3.90.190.20. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR029066. PLP-binding_barrel.
IPR005863. UDP-N-AcMur_synth.
[Graphical view]
PANTHERiPTHR23135:SF3. PTHR23135:SF3. 1 hit.
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF01225. Mur_ligase. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
SSF63418. SSF63418. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparative genome analysis of Prevotella ruminicola and Prevotella bryantii: insights into their environmental niche."
    North American Consortium for Rumen Bacteria
    Purushe J., Fouts D.E., Morrison M., White B.A., Mackie R.I., Coutinho P.M., Henrissat B., Nelson K.E.
    Microb. Ecol. 60:721-729(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19189 / JCM 8958 / 23Imported.

Entry informationi

Entry nameiD5EVJ7_PRER2
AccessioniPrimary (citable) accession number: D5EVJ7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: June 24, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.