Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

D5EU48 (D5EU48_PRER2) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165 HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding20 – 278ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding92 – 954ATP By similarity HAMAP-Rule MF_00124

Sites

Active site931Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1491Zinc By similarity HAMAP-Rule MF_00124
Metal binding1521Zinc By similarity HAMAP-Rule MF_00124
Metal binding1811Zinc By similarity HAMAP-Rule MF_00124
Metal binding1841Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
D5EU48 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: 76B3936E72D50FFA

FASTA20022,435
        10         20         30         40         50         60 
MIENLTGEAH RPGRIEVVCG SMFSGKTEEL IRRMRRAQFA RQKVEIFKPA IDVRYSEEDV 

        70         80         90        100        110        120 
VSHDQKHIQS TPIDSPGSIL LLSSDIDVVG IDEAQFFDMG IVDVCNELAN RGVRVIVAGL 

       130        140        150        160        170        180 
DMDYKGVPFG PMPALCAIAD DVTKVHAICV KCGNLAYVSH RKVQSEQRVL LGETTEYEPL 

       190        200 
CRECYQKAIR EENERKDNHA 

« Hide

References

[1]"Comparative genome analysis of Prevotella ruminicola and Prevotella bryantii: insights into their environmental niche."
North American Consortium for Rumen Bacteria
Purushe J., Fouts D.E., Morrison M., White B.A., Mackie R.I., Coutinho P.M., Henrissat B., Nelson K.E.
Microb. Ecol. 60:721-729(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 19189 / JCM 8958 / 23.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002006 Genomic DNA. Translation: ADE81888.1.
RefSeqYP_003575152.1. NC_014033.1.

3D structure databases

ProteinModelPortalD5EU48.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADE81888; ADE81888; PRU_1868.
GeneID9001142.
KEGGpru:PRU_1868.
PATRIC35497877. VBIPreRum14515_1815.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000076390.
KOK00857.

Enzyme and pathway databases

BioCycPRUM264731:GHX6-1805-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD5EU48_PRER2
AccessionPrimary (citable) accession number: D5EU48
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: April 16, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)