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D5ECS6

- D5ECS6_AMICL

UniProt

D5ECS6 - D5ECS6_AMICL

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Protein

Alanine racemase

Gene
Amico_0212
Organism
Aminobacterium colombiense (strain DSM 12261 / ALA-1)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei37 – 371Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei135 – 1351Substrate By similarityUniRule annotation
Active sitei264 – 2641Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei313 – 3131Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciACOL572547:GHQ0-212-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Amico_0212Imported
OrganismiAminobacterium colombiense (strain DSM 12261 / ALA-1)Imported
Taxonomic identifieri572547 [NCBI]
Taxonomic lineageiBacteriaSynergistetesSynergistiaSynergistalesSynergistaceaeAminobacterium
ProteomesiUP000002366: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei37 – 371N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD5ECS6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiHVANSYI.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

D5ECS6-1 [UniParc]FASTAAdd to Basket

« Hide

MSWRPTRLEV DLEKVRNNYR AIRKHVGESV RIFGVVKGDA YNLGADKIGR    50
VLADMGVDFF AVATGDEAIS LRESGIESPI LVLGPSPYGI AEEYVRLGIR 100
AAINDKGIAK ALSDASVRLQ KPAYGHVKID SGMGRIGFFP HEAADAVEEI 150
SHLPGLNLEG IFTHFAISDA RDLTYTYEQH STFVKVIGEL EKRGITFSIK 200
HCCNSGATLA LPQFVMDGVR PGQLVVGMYP SKEVVRSIAI EPVFEFKTAI 250
SAIRTVPAGK KLSYGLTYET TADERIAVIP VGYHDGYSRE LSGKGTEVLI 300
HGKRCPIVGR ICMDQALVDV SVLQNPQIGD EVVLLGKQGE ETITGDEIAD 350
KIGTIFTTLP NMIGKRVPRV YLNE 374
Length:374
Mass (Da):40,802
Last modified:June 15, 2010 - v1
Checksum:iEBADE8BFCFA1E59F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001997 Genomic DNA. Translation: ADE56358.1.
RefSeqiWP_013047624.1. NC_014011.1.
YP_003553082.1. NC_014011.1.

Genome annotation databases

EnsemblBacteriaiADE56358; ADE56358; Amico_0212.
GeneIDi8963110.
KEGGiaco:Amico_0212.
PATRICi35452560. VBIAmiCol31354_0222.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001997 Genomic DNA. Translation: ADE56358.1 .
RefSeqi WP_013047624.1. NC_014011.1.
YP_003553082.1. NC_014011.1.

3D structure databases

ProteinModelPortali D5ECS6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE56358 ; ADE56358 ; Amico_0212 .
GeneIDi 8963110.
KEGGi aco:Amico_0212.
PATRICi 35452560. VBIAmiCol31354_0222.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.
OMAi HVANSYI.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci ACOL572547:GHQ0-212-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 12261 / ALA-1.

Entry informationi

Entry nameiD5ECS6_AMICL
AccessioniPrimary (citable) accession number: D5ECS6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: September 3, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi