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D5ECQ3

- D5ECQ3_AMICL

UniProt

D5ECQ3 - D5ECQ3_AMICL

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Protein
Submitted name:

D-alanine--D-alanine ligase

Gene
Amico_0188
Organism
Aminobacterium colombiense (strain DSM 12261 / ALA-1)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cell wall formation By similarity.SAAS annotations

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotations

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.SAAS annotations

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  2. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationsImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotations, Peptidoglycan synthesisSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, MagnesiumSAAS annotations, ManganeseSAAS annotations, Metal-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciACOL572547:GHQ0-188-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Ordered Locus Names:Amico_0188Imported
OrganismiAminobacterium colombiense (strain DSM 12261 / ALA-1)Imported
Taxonomic identifieri572547 [NCBI]
Taxonomic lineageiBacteriaSynergistetesSynergistiaSynergistalesSynergistaceaeAminobacterium
ProteomesiUP000002366: Chromosome

Subcellular locationi

Cytoplasm By similarity SAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliD5ECQ3.

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000011592.
KOiK01921.
OMAiFLEVNPL.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5ECQ3-1 [UniParc]FASTAAdd to Basket

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MERRHEEERE NPLPLKKRKK EVQVIGITYN LRKDAQADEP DDIYEEYDCL    50
ETVEALSNEI ASLGFQVFLF EQNELLLQKL DSIAPDFVLN IAEGLGNYRG 100
RESQVPCILE SLNIPFSGSD SASLAIALDK VLTSHVLRAS NIPAPKNYVA 150
KLPQDTTEKK VIFNTCQKYI IKPRWEGSSK GIFLDSIADT PEKVKTCIKR 200
IWERYNQPAI VEEFLPGIEI TAGVAGNTQP KCIGMMSITP VTENSSFLYS 250
LEEKRNYLER IRYSGPDSMS PQLRKKIGDL AVRAFKALEL RDIARIDFRL 300
DDKGQPRVID INPLPGLSPA YSDLPILYRL SGGEYSELIQ TILREAFSRY 350
GLCAPCLNKP ELVREKA 367
Length:367
Mass (Da):41,517
Last modified:June 15, 2010 - v1
Checksum:i02D15E90D7BF5105
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001997 Genomic DNA. Translation: ADE56335.1.
RefSeqiWP_013047601.1. NC_014011.1.
YP_003553059.1. NC_014011.1.

Genome annotation databases

EnsemblBacteriaiADE56335; ADE56335; Amico_0188.
GeneIDi8963086.
KEGGiaco:Amico_0188.
PATRICi35452510. VBIAmiCol31354_0197.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001997 Genomic DNA. Translation: ADE56335.1 .
RefSeqi WP_013047601.1. NC_014011.1.
YP_003553059.1. NC_014011.1.

3D structure databases

ProteinModelPortali D5ECQ3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE56335 ; ADE56335 ; Amico_0188 .
GeneIDi 8963086.
KEGGi aco:Amico_0188.
PATRICi 35452510. VBIAmiCol31354_0197.

Phylogenomic databases

HOGENOMi HOG000011592.
KOi K01921.
OMAi FLEVNPL.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci ACOL572547:GHQ0-188-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 12261 / ALA-1.

Entry informationi

Entry nameiD5ECQ3_AMICL
AccessioniPrimary (citable) accession number: D5ECQ3
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: September 3, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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